'Surprisingly, the protozoan parasite Cryptosporidium emerged second only to rotavirus as a cause of moderate-to-severe diarrhea in children under one year old and continued to be a risk factor in older age groups. While vaccines are available for rotavirus, for Cryptosporidium species there is no vaccine and the only FDA-approved therapy—nitazoxanide—is ineffective in malnourished children and immunocompromised individuals'