'Thus, αCTLA-4 blockade in mesenchymal-like glioblastoma promotes a CD4+T cell-microglia circuit wherein IFNγ triggers microglia activation and phagocytosis and microglia in turn act as antigen-presenting cells fueling the CD4+ T cell response.'

https://www.cell.com/immunity/fulltext/S1074-7613(23)00328-X