"We showed that treatment with an agonist against the tumor necrosis factor (TNF) receptor superfamily member CD40 in combination with a soluble β-glucan (BG), which targets the C-type lectin receptor (CLR) Dectin-1, was sufficient to trigger productive immunosurveillance in ICB-resistant mouse models of pancreatic ductal adenocarcinoma."
#immunology #Immunotherapy #myeloidcells

https://www.science.org/doi/full/10.1126/sciimmunol.adj5097#tab-contributors