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"Here we show that deletion of ST2, the receptor for interleukin (IL)-33, on Treg cells increased granulocyte influx into the lung and increased cytokine production by innate lymphoid and γδ T cells without alteration of adaptive immunity to influenza."
#immunology #MucosalImmunology
@gpollara @cyrilpedia Absolutely true...I have been pondering the role of this kolecule also quite often...and in the context of different inflammatory contexts it seems to play different roles... #inflammation #cytokines #immunology
@cyrilpedia nice study that. IL1-RA often forgotten as a regulatory element. I see it come up often in transcriptomic data, often with proinflammatory cytokines - often wondered if that's an inbuilt counter regulatory homeostatic mechanism. #immunology #bioinformatics