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'Here, we use photo-labeling, combined with longitudinal transcriptomic and cellular analyses, to interrogate the fate of intratumoral NK cells. We reveal that NK cells rapidly lose effector functions and adopt a distinct phenotypic state with features associated with tissue residency.'

nature.com/articles/s41467-024

@cyrilpedia Thank you for sharing! David's work is beautiful and another important piece in the big puzzle of #NKcells in #cancer ...with the other big question: how does the #tumor keep NK cells out of it's #microenvironment ...? @gpollara @chfloudas

Thanks for boosting and tagging me
@halama_immuno , only thing remaining is reading it!

@cyrilpedia
@gpollara

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