"This raises the question of why so many pathways that react to the challenge of infection or tissue injury use mitochondria as a central signalling hub to integrate and transduce the cell’s response. One probable factor is that the endosymbiotic origin of mitochondria marks them apart from the rest of the cell in a way that can be co-opted to produce key messages pertaining to cell fate"

https://www.nature.com/articles/s41586-023-06866-z?utm_medium=Social&utm_campaign=nature&utm_source=Twitter#Echobox=1707326560