Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
"Illustration of evolutionary mechanisms enabling eukaryotic acquisition of innate immune machinery from bacteria. Gray background illustrates bacterial sequences, with transition to white background indicating inheritance by eukaryotes. Through analysis of the evolutionary history of CD-NTase, STING, and viperin proteins, Culbertson and Levin highlight 3 broad mechanisms of eukaryotic immune gene evolution: vertical inheritance from LECA (green clade), horizontal gene transfer to specific eukaryotic clades groups (blue, pink, and tan clades), and convergent domain shuffling where similar accessory domains (red with white hashes) are found fused to the same immune gene (tan clade)."
#Immunology #Evolution
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002481
'The center of the movie, however, is the music. Tavernier, Maxine Gordon writes, “insisted that all the music would be recorded live as the musicians were filmed.” The musicians in “ ’Round Midnight” don’t play watered-down jazz. Although the numbers are condensed, much shorter than is usual on records or in concerts, the performances themselves are almost all full-strength, unadulterated modern jazz.'
https://www.newyorker.com/culture/the-front-row/round-midnight-revisited-a-feast-of-music-and-acting
Hen jug. Glazed stoneware by @hunchbacksociety
#art #ceramics #stoneware #ceramic #Pottery #handmade #artgallery #stoneware #artmastodon
@madparreira @jorgenesbitt
"With this perspective, our intent is to provide some orientation—and some sense of calm—while navigating the diversity of CRISPR tools, recognizing what needs to be done to make them better and tackling the technical, regulatory and other challenges. Inspired by Douglas Adams’ classic scientific-fiction comedy novel The Hitchhiker’s Guide to the Galaxy (1979), this article is our attempt to provide a brief, and hopefully informative, tour with this hitchhiker’s guide to the universe of #CRISPR-based editing tools in bacteria."
Krink et al @emboreports
https://www.embopress.org/doi/full/10.1038/s44319-024-00086-w
Jar. Glazed stoneware by @hunchbacksociety
#art #ceramics #stoneware #ceramic #Pottery #handmade #artgallery #stoneware #artmastodon
https://madalenaparreira.com/Hunchbacksociety
Cup & holder by @madparreira.bsky.social
#art #ceramics #stoneware #handmade #artgallery #pottery #ceramic #arts
"Antivaccine perceived experts are therefore overrepresented on Twitter compared to the share of actual biomedical experts who oppose COVID-19 vaccines, which may lead observers to underestimate the scientific consensus in favor of COVID-19 vaccination, in turn reducing vaccine uptake"
https://academic.oup.com/pnasnexus/article/3/2/pgae007/7601415?login=false#438996316
"One of the movie’s nice surprises is that Morricone turns out to be a total charmer, a low-key showman with a demure gaze that he works like a vamp and an impish smile that routinely punctuates one of his anecdotes."
https://www.nytimes.com/2024/02/08/movies/ennio-review-morricone-film-scores.html
Origami map
#print #prints #printmaking#copperprintmaking #copperprint #art #handmade #maps#cartography #artgallery #artmastodon
@madparreira.bsky.social
Lithographic print on wood, 12x15cm by @madparreira.bsky.social
#Art #Prints #Printmaking #Handmade #artgallery #artmastodon
Joana Lobo Antunes @JoanaLA at the Champalimaud PostDoc day, describing the moment when she realised science communication could be more than something you do on the side (spoiler: there was a lot of screaming across age groups).
Butterfly on a wheel. Plate, glazed stoneware by @hunchbacksociety
#art #ceramics #stoneware #handmade #artgallery #pottery #ceramic #artmastodon
@madparreira.bsky.social https://madalenaparreira.com/Hunchbacksociety
That's not a profit margin. *That's*👇 a profit margin
"Relx does not disclose figures for specific journals but reported £2.9bn revenues in 2022 for all scientific, technical and medical products, with an operating profit of £1.1bn."
https://www.ft.com/content/33e41e46-0d5d-480b-ad08-009da434c52f
During the 2020 lockdown @madparreira experimented with making miniature paper sets in tupperwares & lighting them with her cellphone :)
#Art #ArtGallery #Handmade
'Duke Maximilian I of Bavaria had whisked Dürer’s panel off to his private collection in Munich in 1614, just over a century after it was completed, arranging with the Dominicans for a copy to replace it. This copy is now in the Historisches Museum in Frankfurt, and although it lacks Dürer’s skilled brushwork and glorious colors, it allows us to see his design and in particular one daring, even shocking, detail. Just to the left of center Dürer painted his own portrait: an isolated figure in a recognizably German landscape, poised between the apostles looking up in awe and the Madonna floating above. He holds a board with “credits larger than a shop sign” declaring that he, Albrecht Dürer, had created this picture, ending with a large version of his monogram, “AD.”'
Jenny Uglow @nybooks
#Art #ArtHistory #Durer https://www.nybooks.com/articles/2024/02/22/in-search-of-the-rare-and-strange-durers-lost-masterpiece/
"For these reasons, we hypothesize that PTMs could have been selected throughout evolution at the flanks of aggregation-prone regions as an intrinsic factor to protect proteins against aggregation, thus expanding the current repertoire of aggregation gatekeepers."
"We generated mice for the B cell–conditional expression of the most frequent BTG1 mutation [Gln36→His (Q36H)]. Btg1Q36H cells almost completely outcompeted their wild-type counterparts, specifically in the GC. This competitive fitness manifested as a stronger induction of MYC-dependent growth programs."
#immunology
Madalena's Lion King masks, all made from paper/cardboard. @madparreira
#art #arts #theaterarts #theater #handmade
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
