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If we write, a la Conan Doyle, "We are discovered. Flee at once," meet us at the sign of the purple elephant @PLOSBiology

"In January 2022, we reported the most comprehensive estimates of the global burden of bacterial antimicrobial resistance (“the GRAM report”), estimating that antimicrobial resistance was a contributing factor in 4.3 million deaths in 2019; of those, 1.27 million deaths were directly attributable to antimicrobial resistance (AMR) [1,2]. The study highlighted inequities, with the all-age death rate attributable to AMR highest in sub-Saharan Africa (23.7/100,000), despite this region not having the highest AMR prevalence, but because of the high infectious disease burden and fragile health systems."

journals.plos.org/plosbiology/

Hey! We are brand new here. Hoping our 35,000 twitter followers + loads of new friends will join us to share our love of Folklore Films! #RIPTwitter

And remember, there is still love, light and beauty in the world!

'Papageno' (1935) dir. Lotte Reiniger.

Another #introduction for the latest wave!

I am a professor at Arizona State University. My lab studies host-beneficial #microbial infections in #eukaryotic cells. We are interested in how these infections are similar to and different from #pathogens, #mitochondria, and #plastids. We use #EvolutionaryBiology, #CellBiology, #genomics, #biochemistry, and #imaging as tools, and mostly study #bacteria that infect #insect cells but also work in other cool systems such as #plants and #lichens.

#Introduction time. I’m a postdoctoral research associate at the University of Glasgow
Research interests include #adipocytes #adiposetissue #metabolism #immunometabolism #immunity and #IL-17 ! 
I also founded The STEM Village, an initiative to promote visibility of #LGBTQ people in #STEM 🏳️‍🌈🏳️‍⚧️🏳️‍🌈🏳️‍⚧️🏳️‍🌈🏳️‍⚧️ you can find out more on our website thestemvillage.com or our #YouTube channel youtube.com/channel/UCULuHvpzP

"Madi et al. report the surprising finding that human and murine FOXP3+ Tregs are a physiological relevant source of Interleukin-15, a homeostatic cytokine that promotes antigen-independent maintenance of CD8+ memory T-cells. In mice that lack IL-15 selectively in FOXP3+Tregs the authors show that the composition of the CD8+ T-cell memory pool is altered in the absence of Treg-derived IL-15, since a subset of terminally effector memory cells is drastically reduced."

onlinelibrary.wiley.com/doi/ab

Lecturing on color vision today. The photographer in me always has to talk about the first color photo. Produced in 1861 by Thomas Sutton for James C. Maxwell, based on his three color additive method. A tartan coloured ribbon was photographed through red, green, and blue filters.

Hey #ChemiVerse

Nature Chemistry is recruiting for a full-time editor!

The ideal candidate will have expertise in chemical biology or biological chemistry.

Closing date for applications: 12th December

Locations: London, Berlin, New York, Shanghai

#Editorial #Publishing #Chemistry #Jobs #ScienceJobs #ChemJobs

Boosts appreciated!

careers.springernature.com/job

Happy #LGBTQSTEMDay everyone!

Looking forward to the panel discussion later with the microbiology society 🏳️‍🌈

Here’s a little interview from me: microbiologysociety.org/blog/l

@gregggonsalves Getting my notebook ready for this thread (if that's what we're calling them here, some wit suggested 'tootpaste')

Getting ready to teach in the spring and wanted to just give a shout-out to books that I've used at various points during the past five years of teaching "Political Epidemiology." First up... a🧵 1/

Hi everyone. We’re #Co_Biologists, a not-for-profit #publisher dedicated to inspiring the #biology community:

- We publish five #journals: @Dev_journal @J_Cell_Sci @J_Exp_Biol @DMM_Journal & @BiologyOpen
- We facilitate scientific #meetings & provide #grants for #researchers
- We run three #community sites: @the_node @preLights @focalplane_jcs
- We are committed to #OpenAccess
- We have initiatives to support early-career researchers #ECRs

#Introduction #DevBio #CellScience #Disease #Science

My Editor's Choice in #Science (@sciencemagazine) this week highlights work in the Journal of Clinical Investigation by Johanna Strobl, Georg Stary, & colleagues. The authors describe the effects of #tick bites on the #ImmuneSystem & develop an ex vivo #human #skin #explant model of #LymeDisease!

Editor's Choice : bit.ly/EC221118
Article: bit.ly/3USYkbR

#Borrelia #borreliosis

We're looking for a wet lab postdoc with CRISPRi/a or CRISPR/Cas9 experience to investigate enhancers in human ES cells qmul.ac.uk/jobs/vacancies/item. Friendly lab, great colleagues, excellent environment, part of the QMUL chromatin and epigenetics community. Get in touch if you're interested. Pls share.

Kafka's parables at the London Review of Books:

"Leopards break into the temple and drink the sacrificial vessels dry; this is repeated over and over; eventually it can be calculated in advance and becomes part of the ceremony.

They were offered the choice between becoming kings or the couriers of kings. In the manner of children, they all wanted to be couriers. And so there are only couriers. They rush through the world and, as there are no kings, they shout their now meaningless messages to one another. They would gladly put an end to their wretched lives, but don’t dare to because of their oaths of service."

lrb.co.uk/the-paper/v44/n22/mi

"Here, we establish microglia as a new cellular component of the sleep homeostasis circuit. Using quantitative phosphoproteomics of the mouse frontal cortex, we demonstrate that microglia-specific deletion of TNFα perturbs thousands of phosphorylation sites during the sleep period. Substrates of microglial TNFα comprise sleep-related kinases such as MAPKs and MARKs, and numerous synaptic proteins, including a subset whose phosphorylation status encodes sleep need and determines sleep duration."

embopress.org/doi/abs/10.15252

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