Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Neuro-evo conference at HHMI Janelia on May 15-18, 2023. Join us for the third edition!
Application deadline: Jan 27 (11:59 p.m. EST) 2023.
"Historically, with the study of the most convenient animal models —from the giant axon of the squid and the lobster's stomatogastric circuits to Aplysia's synapses and C. elegans' circuits — neuroscientists revealed some of the operating principles of the nervous system, which were then found to apply broadly across phyla. The third instalment of this meeting will once again bring together neuroscientists working on a broad diversity of animal models in an effort to compare circuits across phyla as a means to crack their function."
#NeuroEvo #Janelia #HHMI #conference #science #academia #neuroscience #DevBio #connectomics #connectome
Thiago Carvalho
boosted
RT @eLife@twitter.com
An improved culture method for Drosophila allows live-imaging of organs outside the body for up to 3 days. https://elifesciences.org/articles/76010?utm_source=twitter&utm_medium=social&utm_campaign=organic
Thiago Carvalho
boosted
Hello fellow #Mastodonians! #introduction
I am a nurse practitioner and clinical scientist at #MIT. I am also #disabled, a mama of an awesome kid, and a wife to a wonderful man who is also collegiate track coach.
My work focuses on researching sexual dimorphism and sex differences in immune response and disease presentation, specifically in relation to chronic illness, #Lyme disease, & #LongCOVID.
Happy to be here and continue to advocate and #DemandBetter while my body still allows me to!
@ImmunoFever Welcome aboard Michal!
Thiago Carvalho
boosted
#introduction:
I'm here following my #ScienceTwitter crew on this #TwitterMigration. Hoping we can all reconnect. I run a group at MIT diving deep into the immunological underpinnings of some of the most misunderstood and neglected chronic diseases in modern medicine. I specialize in chronic #Lyme and I'm also trying to understand why that looks so much like long COVID. I'm obsessed with mucosal immunology, sex differences in immune responses to infectious disease, and the health of this planet.
@Caroline_Bartma I think these are good targets for plasma cell derived tumors - especially if you factor in the entire cycle of protein homeostasis, with proteasome inhibitors being a big deal in the clinic. But the basic issue is what do you expect the side effect profile to be? Targeting nucleic acid synthesis is broad, but still the list of fast dividing host tissues/cells at any given timepoint might be significantly larger than those doing medium to high level protein synthesis. With plasma cells being just one big outlier.
Thiago Carvalho
boosted
RT @saramitri@twitter.com
Open postdoc position: we are looking for a chemist interested in how microbial communities transform their environments (machine oils and bioplastics). Come work with a fun, interdisciplinary group in Lausanne, Switzerland. Apply here by 31.12. https://career5.successfactors.eu/sfcareer/jobreqcareer?jobId=20593&company=universitdP or RT
🐦🔗: https://twitter.com/saramitri/status/1594620109301186560
"This weary skepticism for the scientific endeavor rings through many of Vonnegut’s 14 novels and dozens of short stories. For what would have been the famed author’s 100th birthday, Science talked to literary scholars, philosophers of science, and political theorists about the messages Vonnegut left for the scientific community—and why he’s more relevant than ever."
Thiago Carvalho
boosted
New paper -- Do genes and languages evolve together? Not always!
"Activity tracing by plasma proteomic profiling uncovered an association between low NET clearance and increased COVID-19 pathology and mortality. Low NET clearance activity with comparable proteome associations was prevalent in healthy donors with low-grade inflammation, implicating defective chromatin clearance in the development of cardiovascular disease and linking COVID-19 susceptibility to pre-existing conditions"
#Immunity #Immunology
#Neutrophil #COVID19 #Pathology
https://www.cell.com/immunity/fulltext/S1074-7613(22)00597-0
Thiago Carvalho
boosted
RT @IMPvienna
What determines our organs' architecture? How can we measure, predict, and manipulate it? Scientists around Keisuke Ishihara @IshiharaKsk from the lab of Elly Tanaka (@tanaxolotl) have tackled the question using neuroepithelial #organoids. (1/4)
https://www.nature.com/articles/s41567-022-01822-6
"In the monkeypox outbreak that unspooled this summer in the United States and dozens of other countries, men who have sex with men were the most at risk. But thousands of women were also infected, and many more cases were probably missed, according to the first ever study of women and nonbinary people who had contracted the disease."
@evepoole@zirk.us @JohsEnevoldsen I made this my browser's homepage.
Thiago Carvalho
boosted
This week is World #AntimicrobialResistance Awareness Week, so we invite you to check out our interview with Dr Jyoti Joshi from the International Centre for Antimicrobial Resistance Solutions. She told us about her work in #AMR control and how she actively engages with communities & high-level policymaking in several Asian countries, and globally, to drive significant progress in public health. We thoroughly enjoyed chatting with Jyoti & hope you enjoy the read!
🦠https://journals.biologists.com/dmm/article/15/7/dmm049626/275489/
Thiago Carvalho
boosted
RT @christinerbeck@twitter.com
Celebrate each win. Paper out today is a big one from our lab, examining a mechanism underlying variation between human genomes. We find hundreds of transposon-mediated rearrangements per genome, and can identify them with either @PacBio@twitter.com sequencing-based assembly or short reads
🐦🔗: https://twitter.com/christinerbeck/status/1594748726798843904
'Covid-19 cases in China are spiralling towards record highs, forcing officials to again lock down large swaths of the country.
The world’s second-biggest economy reported nearly 28,000 new Covid cases on Tuesday, with outbreaks in the Chinese capital, the southern manufacturing hub of Guangzhou and the southwestern metropolis of Chongqing continuing to grow.'
https://www.ft.com/content/f724e3ad-8cae-4f00-8ad2-aa8a5c035fe9
Thiago Carvalho
boosted
A new #SpatialTranscriptomics technique was published on Cell! The authors used polony gels to capture the RNA in situ, and used pixel-seq to map #singlecell transcriptomes back to the tissue. Amazing experimental design! https://www.cell.com/cell/fulltext/S0092-8674(22)01367-8
Thiago Carvalho
boosted
New #introduction for #twitterMigration.
Hello Mastodon community!
In my lab we work with #stemcells #iPS cells and their differentiation into #neurons and brain #organoids.
We focus on #RareDiseases affecting #mitochondria and energy #metabolism. We develop high-content #microscopy assays for #screening repurposable drugs .
Thiago Carvalho
boosted
Absolutely fascinating paper by the group of Ed Feil on Klebsiella genomics
https://www.nature.com/articles/s41564-022-01263-0
A large-scale genomic snapshot of Klebsiella spp. isolates (n = 3,482) in Northern Italy reveals limited transmission between clinical and non-clinical settings
Relevant quote from abstract
"Although we noted occasional transmission between clinical and non-clinical settings, our data point to a limited role of animal and environmental reservoirs in the human acquisition of Klebsiella spp."
Thiago Carvalho
boosted
RT @LauCan88
📢 Two postdoc positions in Machine Learning for single-cell genomics open in my team @IBENS_ENS, @InstitutPrairie and soon @institutpasteur
in collaboration with @gabrielpeyre @ENS_ULM
PM me if interested
RT please🙏!
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
