Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
'During the last decade, the stimulation of T-cell function by the blockage of immunosuppressive checkpoints has experienced an outstanding impact in the treatment of cancer. Development of the chimeric antigen receptor T-cell technology has also emerged as a powerful alternative for patients suffering from oncological processes, especially those affected by hematological neoplasms. Recent evidence suggest that the use of immunotherapy could be extended to non-oncological diseases and could be especially relevant for age-associated disorders, opening exciting therapeutic options for a wide range of diseases of the elderly.'
https://www.embopress.org/doi/full/10.15252/emmm.202216301
'A confidential memo said that the collection included the bones of Mamadou Lamine, a 19th-century West African Muslim leader who led a rebellion against French colonial troops; a family of Canadian Inuits exhibited in a Paris human zoo in 1881; and even five victims of the Armenian genocide in the mid-1910s.
“Sometimes, the supervisors would say, ‘We must hide,’” said Philippe Mennecier, a retired linguist and curator who worked for four decades at the Museum of Mankind. “The museum is afraid of scandal.”
Thiago Carvalho
boosted
Hi Mastodon! I'm a journalist at @sciencemagazine, where I delve into stories about the scientific community and the various challenges that come with pursuing a career in science. I'm a former scientist myself—I earned a Ph.D. in ecology and did a stint as a postdoc before realizing that the best career path for me lay elsewhere. Feel free to get in touch if you'd like to introduce yourself or suggest a story idea. #ScienceMastodon #academicchatter
Thiago Carvalho
boosted
#OnThisDay, 28 Nov 1967, PhD student Jocelyn Bell Burnell discovers the existence of pulsars.
Not included in the 1974 Nobel prize for the discovery, Bell received a £3m prize for her work in 2018. She's using it to set up a foundation to improve diversity in STEM.
@christlet Also, it seems that many people who didn't quit didn't get paid because
"Much of Twitter's payroll staff resigned in mid-November after Musk's work-long-hours-or-quit ultimatum."
@dr_marcomeer@mastodon.green It is!
Thiago Carvalho
boosted
RT @niaidcivics
The Duke Human Vaccine Institute @TheDHVI is hiring for a Scientific Program Leader! This role is responsible for managing research programs through the entire translational pipeline in collaboration with other DHVI leaders. Apply here: https://careers.duke.edu/job/Durham-SCIENTIFIC-PROGRAM-LEADER-I-NC-27710/934770300/
Thiago Carvalho
boosted
Our team is hiring ! We are looking for three postdoctoral researchers in the field of atomic force microscopy #AFM, single molecule fluorescence spectroscopy (#smFRET) and #DNAorigami.
More info & application process here.
https://integrativebiophysicsofmembranes.wordpress.com/2022/11/28/now-hiring/
Please spread the info !
Thiago Carvalho
boosted
Calling all UK-based early career woman scientists! Please apply for the L’Oréal For Women in Science Fellowship. The deadline is 02/12, the application is super short (500 words!!) and the £15k is flexible. Happy to help talk through your proposal/ personal statement. Please email me! https://www.forwomeninscience.com/challenge/show/58 #WomenInSTEM #ChemToots #ChemMastodon #ScienceMastodon
'There is no doubting the centrality today of Mendel’s ideas in evolutionary biology. The current theory’s foundation, the modern synthesis, depends arguably as much on Mendel as it does on Darwin. The 200th anniversary of Mendel’s birth is thus an appropriate moment for both reevaluating and celebrating his legacy in evolutionary biology.'
Thiago Carvalho
boosted
Job: Theoretical eco-evo postdoc in Mainz (Germany)
I realize I posted this one back then on a site that wasn't owned by Musk yet; never here so far. Also, the deadline is conveniently a week away (4th Dec to be precise) so a reminder is in place anyway!
My lab is moving to the University of #Mainz. If you're into #LifeHistory #theory/#modelling and would like to interact with whoever visits the future "theory hub" of the #Kokkonuts, read this ad!
https://evol.mcmaster.ca/~brian/evoldir/PostDocs/UMainz.TheoreticalEvolutionaryEcology
@jobsecoevo
Thiago Carvalho
boosted
In Science Signaling, Ye, Olsen, Wandall, and colleagues used a 3D human organotypic skin model to investigate signaling by the protein TGF-beta. Although TGF-beta initially suppresses tumor growth, at later stages, it promotes metastasis. With this approach, the researchers identified a TGF-beta signaling pathway that promoted invasive growth. This same setup can be used by others to study TGF-beta signaling under normal and pathological conditions: https://www.science.org/doi/10.1126/scisignal.abo2206 #science #cancer
Thiago Carvalho
boosted
Neuro-evo conference at HHMI Janelia on May 15-18, 2023. Join us for the 3rd edition!
Application deadline: Jan 27 (11:59 p.m. EST) 2023.
"The third instalment of this meeting will once again bring together neuroscientists working on a broad diversity of animal models in an effort to compare circuits across phyla as a means to crack their function."
#NeuroEvo #Janelia #HHMI #conference #science #academia #neuroscience #DevBio #connectomics #connectome
Thiago Carvalho
boosted
For those that joined #Mastodon and grabbed the first server they could find, but would prefer to #migrate to a different one, I created a short guide on how to do this quickly and easily.
It also allows you to easily move any followers across to your new profile and leaves a redirection on your old profile for those that find it to help them get to your new one. 😁👍
I'd love if you could share it among your networks to help those that will invariably need it later on.
https://youtu.be/BpI-SplOXVE
Thiago Carvalho
boosted
"A higher aneuploidy score is associated with poor prognosis following immunotherapy among tumors with low TMB, but not those with high TMB."
Thiago Carvalho
boosted
An impressive visualization of the SARS-CoV-2 life cycle. https://www.youtube.com/watch?v=XlOi2hVGtg0&t=2s
'Interestingly, combined treatments including phages and a wide range of antibiotics lead to an increased bacterial killing, a phenomenon called phage-antibiotic synergy (PAS), suggesting that antibiotic-induced changes in bacterial physiology alter the dynamics of phage propagation. Using single-phage and single-cell techniques, each step of the lytic cycle of phage HK620 was studied in E. coli cultures treated with either ciprofloxacin or cephalexin, two filamentation-inducing antibiotics.'
#Phage #Antiobiotics #preprint
https://www.biorxiv.org/content/10.1101/2022.11.28.518157v1?med=mas
Thiago Carvalho
boosted
3,013 neurons, half a million synapses: the complete #connectome of the whole #Drosophila larval brain!
Winding, Pedigo et al. 2022. "The connectome of an insect brain" https://www.biorxiv.org/content/10.1101/2022.11.28.516756v1
We’ve mapped and analysed its circuit architecture, from sensory neurons to brain output neurons, as reconstructed from volume electron microscopy, and here is what we found. 1/
Thiago Carvalho
boosted
Hospital wastewater shouldn't be a reservoir for *any* antimicrobial resistance really...😓 
#AMR #IDMastodon #microbiology https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(22)00326-3/fulltext?dgcid=raven_jbs_aip_email
Thiago Carvalho
boosted
Preparations are well underway for #DevMeeting23 on ‘Unconventional and Emerging Experimental Organisms in Cell and Developmental Biology’, organised by @sarur @jamesbriscoe Gautam Dey and Cassandra Extavour.
Our meeting page is live and you can check out the list of confirmed speakers and register for updates on the programme and key dates.
https://www.biologists.com/meetings/unconventional-organisms-23/
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
