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#IDMastodon Omicron variants bind with higher affinity to motile cilia and show accelerated viral entry. In this #Clinicalstudy that motile cilia, microvilli, and mucociliary-dependent mucus flow are critical for efficient virus replication in nasal epithelia. @CellCellPress . Based on this study ,please wear n-95 😷 wherever you are & mostly in enclosed places to minimise the rate of #SarsCoV2 infection & reduce that’s hight viral loads
cell.com/action/showPdf?pii=S0

4 lectureships in #neuroscience in Bristol, UK. (2 junior, 2 senior).

Offers £39,745 - £68,823. (Not a typo, unfortunately.)

Not wanting to single out Bristol here, note all UK universities offer these ridiculously low salaries. The expectation, I can only guess, is that your partner with a higher salary subsidises the university via the institution of marriage, or you are independently wealthy, or choose not to have a family.

bristol.ac.uk/jobs/find/detail

Big Cheese did it

"The popularity of fondue wasn't an accident. It was planned by a shadowy association of Swiss cheese makers. A cheese cartel basically ruled the Swiss economy for 80 years, until fairly recently."

npr.org/2015/04/23/401655790/h

More arguments for intranasal influenza vaccination, from Marco Künzli at David Masopust’s lab: “Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells”. science.org/doi/epdf/10.1126/s

"Immune checkpoint inhibitors such as pembrolizumab or nivolumab, which inhibit PD-1, have greatly improved survival for many patients with cancer, but are prohibitively expensive and unattainable for most of the global cancer population. Optimized dosing, with a reduced unit dose, less frequent schedule and/or shorter duration of treatment could reduce costs and potentially toxicity, thereby improving global access to effective cancer therapy."

nature.com/articles/s41591-022

"Unbeknownst to me as a young physician, certain scholars and pundits in the 1960s were opining that with the advent of highly effective vaccines for many childhood diseases and a growing array of antibiotics, the threat of infectious diseases — and perhaps, with it, the need for infectious-disease specialists — was fast disappearing."
- Anthony Fauci

nejm.org/doi/full/10.1056/NEJM

RT @_dmoser
It's official: France bans short haul domestic flights ✈️ in favour of train 🚆 travel 👇👇
buff.ly/3gVzNUR

I recently found this picture, taken in the 1930s at Le Monocle, one of the lesbian nightclubs in Paris at the time.

It's a great picture, with a lot of different people, absorbed in their own merriment, and at the center, my new reference for the concept of badass.

I don't know who she is, but she deserves a long, adventurous backstory -- maybe involving mutiny aboard an airship, spies, and broken hearts.

She's the only one looking at the camera, so the story is definitely about her.

"Quammen, 74, is the favorite science writer of many people who don’t usually read science writing. He also happens to be the favorite science writer of many science writers, a foundational figure. Among the kinds of people who cover anything from space telescopes to treatment-resistant bacteria, Quammen is a writer to geek out over."

theatlantic.com/books/archive/

Map shows planes in the sky around the world. Pretty obvious who's using up the fossil fuels here.

@NicoleCRust Interesting results - it will be fun to see what happens as the networks grow. The anecdotal feedback I get from friends is that the science content is getting better all the time on Mastodon, but they miss the cultural accounts from the bird site (the Albrecht Dürer and El Greco bots, for example - though I already see a lot of great photography here).

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