Thiago Carvalho @cyrilpedia@social.cleverlibre.org

@halama_immuno Absolutely - also highlights the need to keep an eye on CD4 cells when following the effects of things like checkpoint inhibitors, there is a bit a too much tunnel vision around CD8s in a lot of the ICI literature.

Great animation over at @aeon_co

'Growing up in the 1940s, Ronald Clark had an experience that sounds as if it was plucked from a children’s book – he lived in a New York City public library. And indeed, he believed that living in this ‘temple of knowledge’, where his father worked as a custodian, was a grand privilege, even as it led to feelings of difference among his peers'

https://aeon.co/videos/ronald-grew-up-in-a-new-york-city-library-it-was-as-strange-and-wondrous-as-it-sounds

@bn@toot.community I understand - for me, publication in predatory journals with bad peer review is worse than a preprint because it carries the imprimatur of "peer review". It won't fool a researcher in the filed, but a journalist, a doctor, or an immunologist reading a neuroscience paper might be taken in. Whereas with the preprint, your guard is up. And responsible science writers add a "this has not yet been peer reviewed" disclaimer

From a meeting report in #JournalImmunology:

"He (Jonathan Kagan) showed that old mice lose their naive CD8+ T cell repertoire, and the absence of CD8+ T cells in young mice reduces their survival rate. Protective immunity against cancer rises from CD4+ T cells in old mice, whereas CD8+ T cells are responsible for antitumor immunity in young mice."

#Immunotherapy #Immunology #TumorImmunology

https://journals.aai.org/jimmunol/article/209/12/2251/237566/Shedding-Light-on-Immunological-Research-in-Lyon

@warkittens Does that make Gary Busey Ian MacShane?

'Constanze Stelzenmüller, director of the Center on the US and Europe at the Brookings Institution, has said Germany is a case study of a western state that made a “strategic bet” on globalisation and interdependence — and was now suffering the consequences.

“It outsourced its security to the US, its export-led growth to China, and its energy needs to Russia,” she wrote in June. “It is now finding itself excruciatingly vulnerable in an early 21st century characterised by great power competition and an increasing weaponisation of interdependence by allies and adversaries alike.”

https://www.ft.com/content/50a462b3-0e8b-49e1-873c-9505760d4a66