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Ken Murphy's lab (once again) defines a novel mechanism whereby CD4 T cells provide help to cDC1-CD8 T cell responses.

nature.com/articles/s41590-022

"Thus, CD40 signaling in cDC1s not only induces costimulatory ligands for CD8+ T cells but also induces Bcl2l1 that sustains cDC1 survival during priming of anti-tumor responses." #Immunology

On a damp Sunday, it’s time for an #introduction. I am a…

🤖 chemist at Imperial College London, using computer simulations to model crystals. I have a mild obsession with the mineral #perovskite and #openscience

📚 editor at JACS, covering #compchem, #AI, and energy materials

🎓 senior tutor, interested in the wellbeing of early career researchers

📽 otherwise, I'm likely to be found in the cinema or hunting down vinyl records in bargain bins

A reminder of why we are trying to make a new and improved science community here on Mastodon.

We love conjugate-vaccines also due to all that :)

RT @casso89@twitter.com

We found T cells specific to #influenza vaccine (Flu), #tetanus toxoid (TT), or #Candida albicans (C.alb) in both CXCR5+ cTfh and CXCR5- non-cTfh subsets, although with different frequencies and effector functions. 4/10

🐦🔗: twitter.com/casso89/status/160

#introduction time! I’m a postdoc at UC Berkeley working in Jamie Cate’s lab. I’m studying how #eIF3 regulates protein translation in stem cells. I’m also interested in #ribosome and #RNA biochemistry. I’m in Mastodon because I’m very tired of the Donalds and the Elons of the world. Besides science, I’m also very passionate about bike riding and spending time outdoors 🌲🚲

#introduction To fill in my profile tags, a thread:

#TrakEM2 open source software mostly for #connectomics, and supports manual and automatically montaging and aligning overlapping 2D image tiles (with #SIFT features and rigid or elastic transformation models), and reconstructing by painting volumes or tracing branched neuronal arbors neurons plus synapses to map a #connectome from #vEM (volume electron microscopy).

See: journals.plos.org/plosone/arti

Git repository at: github.com/trakem2/

Arc Institute is launching the Arc Science Fellows program for early-career scientists to start their own lab right after grad school with $250K/year research budget + salary.

#PhD #academia

arcinstitute.org/jobs/faculty-

Finally taking the time for an #introduction on #mastodon !

I'm a #marine #microbiologist currently leading a #lab at the #EMBL #Heidelberg. My lab is fascinated by the #diversity & #impact of #microbial #interactions across #biological scales, with a particular focus on #eukaryotic #phytoplankton. We think about #symbiosis #epibiosis #viralinfection #singlecell #ecology, often wt #TaraOceans folks⛵

I push for #inclusive #science, and to rethink our #practices in light of #sustainability 🌊

RT @CyrilPedia@twitter.com

You could also read about this on #ScienceMastodon at

@ntoohm

Where you can catch up on more TFh, germinal center biology etc
@victoralab
@kevinng

Vaccine news with @FabrizioChiodo@twitter.com
@FabrizioChiodo twitter.com/casso89/status/160

🐦🔗: twitter.com/CyrilPedia/status/

We are happy to share our new study recently published in the European Journal of Immunology entitled “Clonal composition and persistence of antigen-specific circulating T follicular helper cells”.
onlinelibrary.wiley.com/doi/10

Follicular helper T cells (Tfh) are very important to promote #Bcell response and #antibody affinity maturation. Despite, their blood counterparts circulating Tfh (#cTfh) cells are poorly defined in #human in terms of #antigen specificity and persistence.
Little thread 🧵 1/8

🙏🚨I need your input🚨🙏

I was asked and agreed to write an updated book chapter on #radiopharmaceuticals therapy for the 8th Ed of Principles and Practice of Radiation Oncology (aka Perez and Brady).

What topics do you, my #RadOnc colleagues, want me to cover?

TIA!

If you want an example of just how out of control Elon Musk is. He just lent his voice to calls for the prosecution of a man that has served 5 presidents and who’s only crime was to provide responsible health safety advice to Americans.
Had Trump listened and acted, at least 300,000 More Americans would be sat around the dinner table this Christmas.
He’s and his familial had had to have close protection simply for telling the truth. Take a moment to think about that.

#introduction The mission of the #Auschwitz Memorial is to preserve the site and all remains of the German Nazi concentration & extermination camp.

We commemorate the victims & educate about this part of human #history.

Tragedy of Auschwitz shows where hatred, #antisemitism and contempt for a fellow man led people in the past. Yet, it is a place where we should reflect on our individual and collective #responsibility for the world we live in.

Support our mission online. Amplify our voice.

I don't care what you think of the man, but the idea that Elon Musk, thug and right wing oligarch can amp up hate directed towards one man is evil. It just is. 4/

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Put that into the context of the racist, antisemitic, homophobic hate unleashed on Twitter over the past few months and you can see that Elon Musk loves this, this monetizing of hate, it arouses him, it gets him going. 5/

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But we NEVER rained down threats on anyone. Now Elon Musk on the bird site is tweeting out "prosecute/Fauci." 2/

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This is an 81 year old scientist and physician. He and his family have had death threats for close to three years and needed Secret Service protection. 3/

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