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Since it’s the new year, I figure an #introduction is in order. My name is Taylor, and I’m entering my final year as a #CompBio PhD candidate at Cornell.
My research is primarily focused on using #ML to understand #regulation of gene expression in grasses. I am particularly interested in #representation and #mechanistic modeling.
My other interests include science in the media, supporting Black scientists, and trivia podcasts.
I hope to have some great discussions on here! :dna: :rna:

20+ years in the making for the first full length biography of a Nobel prize winner and pioneer of molecular biology, Salvador Luria. I knew about his science, but it was great to learn about his advocacy for civil rights, anti-war protests, social justice, and fighting for black scientists.

RT @ThomasWidiez@twitter.com

CRISPR-edited plants using graft-mobile gene editing system !!! 😲
@NatureBiotech@twitter.com

▶️Heritable transgene-free genome editing in plants by grafting of wild-type shoots to transgenic donor rootstocks

📖nature.com/articles/s41587-022

🐦🔗: twitter.com/ThomasWidiez/statu

Reaching out to #biology Community College and 2Y faculty - are you interested in participating in an evidence-based teaching practice hybrid course? Please reach out to me - via DM or reply to this post. Please share 🙋‍♀️#DBER #SoTL #STEMeducation #highereducation #STEM 🙌

Ever try to #drug an #oncoprotein only to have the #tumor lose its dependency on it and become drug resistant? Introducing #RIPTACs (Regulated Induced Proximity Targeting Chimeras) in collaboration with #Halda Therapeutics. RIPTACs selectively kill cells by differentially accumulating an antiproliferative agent via an induced Protein:Protein Interaction (#PPI) to a differentially expressed protein. Importantly, target protein function is not needed for RIPTAC action.
biorxiv.org/cgi/content/short/

Postdoc in experimental biophysics @jauffred

Come and join #kbhuni @BioComplex_NBI to do experimental biophysics of large bacterial communities #biofilm #microscopy

bit.ly/3jAEhRG
#ScienceJobs #ScienceJobs #PostdocPosition @UCPH_Research...
bit.ly/3jAEhRG

Hi all,
I'm a scientist in Queensland, Australia. I spent 20-years in virus research/diagnostic development following MedLabSci degree. PhD in virology next. Research grants in discovery, detection & characterisation of respiratory viruses. Published (see ORCID in bio). Started blogging/tweeting hobby. Then spent 5 years in public health virology diagnostics. Fun work. 2021 to now, ran testing lab (ends soon). What's next for Ian🤷?
#Introduction #virus #cats #gardening #numbers #communication

New year, new job?

We're hiring for a research associate position that combines lab manager duties and assistance with research related to tuft cells and type 2 immunity. We've got a really great group of scientists right now, so come join us!

No experience necessary, but would also consider adapting the position for the right candidate. DM me or apply here: uwhires.admin.washington.edu/E

Text Abbreviations for Microbiologists -
made as a birthday card, inspired by Tom Gauld’s science cartoons. Wishing everyone a 2023 filled with minimal WTF (what’s that fungi?) and maximum OMG. #microbiology #sciencecartoon

RT @BrianAdams66
Words have meanings. Let’s make sure our words have the same definitions whether we’re in agreement about COVID-19 or not. Take the word endemic for example. Great read from @MackayIM
“If you are using endemic to mean milder disease, you’re misleading others, and you’re wrong.” twitter.com/mackayim/status/16

@cyrilpedia I know someone with a 2 month interval. Second infection from an event with known index case and the two other individuals closest to index case also infected. We can presume XBF variant given local prevalence in Victoria, AU, points to immune escape from previous likely BA.5 acquired infection in different part of world 2 months earlier. Sequencing not always required for inference! Individual was boosted but not bivalent-boosted.

"Friis has come to believe, however, that the disappearance of the dinosaurs was not even the most interesting development of the Cretaceous period. She is more interested in a pair of easy-to-miss boulders near the feet of the T. rex, which bear impressions of some very old angiosperm leaves."

newyorker.com/science/elements

More generally, it can be hard to find info on CNRS position applications, in particular for international candidates with few connections to the French system. Potential hosting labs should help in this regard! Beyond the general and formal candidate guide, informal guidance provided by each section (criteria, format) can be found here on the CoNRS website: cnrs.fr/comitenational/english

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En train de préparer une candidature CR ou DR à la section 22 du CNRS (biologie cellulaire, développement, evo-devo) ? Quelques conseils pour le formatage des documents que nous avons ajouté à la fin du document établissant les critères de sélection : cnrs.fr/comitenational/evaluat

"In nocturnal rodents, lymphocyte counts in the blood are high during the day, which corresponds to the resting phase of these animals. More specifically, CD4+ and CD8+ T cell numbers in the mouse blood are highest at zeitgeber time (ZT)4–5 (beginning of the day) and lowest at ZT16 (beginning of the night) (20, 21)."

journals.aai.org/jimmunol/arti

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"It has long been recognized that lymphocyte counts in the human peripheral blood vary according to the time of day (15–19). Both CD4+ and CD8+ T cell counts are rhythmic, with peak levels during the night that decline in the morning and stay low during the day. This is true for naive, effector, and memory CD4+ and for naive CD8+ T cell subsets"

journals.aai.org/jimmunol/arti

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