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nature.com/articles/s41590-022

Truly enjoyed this elegant work from Delgoffe lab showing that Tex CD8 T cells display transcriptional and functional similarities with Treg [we see similar things in our data – hopef coming soon]

A short 🧵 👇

Hey there! We’re working on expanding activists’ use of Mastodon for movement-building. Can you help by boosting this toot about the free online trainings coming up with intermediate and advanced tips on ramping up on Mastodon? campaign.openworlds.info/@soci

Solidarity and best wishes for the New Year!
Hannah

@cd24
@cyrilpedia
@fibonaccigirl

RT @MACattackLab
We are looking for a post-doc to study human immune dysregulation syndromes in #StLouis #Immunology #postdocjobs @WUSTLPeds @WashUDPS @WUSTLdbbs @WUSTLImmuno

We partnered with Research!America to survey Americans about their views on brain health and how it affects their lives, as well as their views on brain health research. Read our Executive Overview for key findings from the survey and for steps we and others can take to set priorities to ensure brain research is responsive to societal needs.
dana.org/article/brain-health-

#neurosociety #neuroscience #neuroethics #brain #mentalhealth #brainhealth

RT @FinlayInstituto@twitter.com

En el primer número del 2023 de Anales de la Academia de Ciencias de Cuba (@Anales_ACC@twitter.com) puede acceder al artículo:
📌Diseño, desarrollo y evaluación preclínica de #SOBERANA02: una vacuna cubana contra #COVID19
Acceso en 🔗 n9.cl/g3dgn
#CienciaCubana
#CubaPorLaSalud

🐦🔗: twitter.com/FinlayInstituto/st

"The China CDC analysis showed a predominance of #Omicron lineages BA.5.2 and BF.7 among locally acquired infections. ...
No new variant or mutation of known significance is noted in the publicly available sequence data."

Interesting statement by WHO's Technical Advisory Group on Virus Evolution which met yesterday to discuss the #covid19 situation in #China:

who.int/news/item/04-01-2023-t

Louis Braille was born on this day in 1809, to change the world for millions. He was only a child when he invented his tactile language for the blind. His inspiring story, illustrated: themarginalian.org/2017/03/21/

A great read to close out the year: radially expanding populations decrease competition as they grow (because of expanding available area or volume), which facilitates the survival of unfit mutants and downstream acquisition of compensatory mutations. This can underlie the evolution of resistance to treatment in bacterial biofilms and solid tumors.

#evolution #amr #cancer

nature.com/articles/s41467-022

Bohemian Rhapsody for postdocs

Is this a real job?
Or more like a PhD?
Caught in short contracts
No chance of stability

Open your eyes
Look up to PIs and see
I'm just a postdoc
I get no sympathy
Because I'm easy come, easy go
Stress is high
Pay is low

#academia #university #postdoc #research #queen #tomwilks

"Using detailed epidemiologic data from SARS-CoV-2 surveillance within the California state prison system, we found that vaccination and prior infection reduced the infectiousness of SARS-CoV-2 infections during an Omicron-predominant (subvariants BA.1 and BA.2) period."

nature.com/articles/s41591-022

Announcing the 2023

Paris Spring School in Optical imaging and electrophysiological recording in neuroscience

3-16 May, Paris, France

parisneuro.ovh

Applications open now, deadline 31. Jan.

Please reboost, with apologies for duplicates.

'In “Queenie: Godmother of Harlem,” the forthcoming graphic novel co-authored by the writer Aurélie Lévy and the artist Elizabeth Colomba, a vivid but forgotten historical figure is brought back to life: Stephanie St. Clair, or Queenie, a Black female boss who ran an uptown numbers game during the Harlem Renaissance.'

newyorker.com/culture/culture-

Isaac Asimov:
"I am an atheist, out and out. It took me a long time to say it. I've been an atheist for years and years, but somehow I felt it was intellectually unrespectable to say one was an atheist, because it assumed knowledge that one didn't have...."

'Attempts to eradicate cancer cells expressing unique target proteins, such as antibody-drug conjugates (ADCs), T-cell engaging therapies, and radiopharmaceuticals have been successful in the clinic, but they are limited by the number of targets given the inability to target intracellular proteins.'


biorxiv.org/content/10.1101/20

Instead of improving #US #copyright law to match the better terms in #Canada, my country pressured Canada to maim its copyright law to match the worse terms in the US.
ctvnews.ca/politics/canada-ext

"There will be no new books, songs or plays added to the public domain in Canada until 2043…The change brings Canada into compliance with a commitment it made under the new North American free trade deal to match its copyright protections with those in place in the United States since 1998."

"While the evolution of immune genes is often interpreted with host phylogeny as a principle explanatory factor [7,46], host ecology can be a stronger driver of microbiome community structure [47]. ... Here we identify how specific effectors evolved to constrain the growth of specific microbes, finding that host ecology, not host phylogeny, makes sense of effector-microbe specificity."

Lines we wrote following some nice work by @markella_moraitou 🙂 : ecoevo.social/@markella_morait

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