Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Alentejo.

"T cell-dependent bispecific antibodies induce adverse systemic changes in addition to tumor killing. This study shows how different vascular beds respond to cancer immunotherapy, suggesting that reducing leukocyte-endothelial interactions may limit the accumulation of T cells, thereby alleviating off-tumor adverse responses."
Himmels et al @emboreports
#immunology #immunotherapy #BispecificAntibody

"Finland ranked No. 1 of 41 European countries on resilience against misinformation for the fifth time in a row in a survey published in October by the Open Society Institute in Sofia, Bulgaria. Officials say Finland’s success is not just the result of its strong education system, which is one of the best in the world, but also because of a concerted effort to teach students about fake news. Media literacy is part of the national core curriculum starting in preschool."

https://www.nytimes.com/2023/01/10/world/europe/finland-misinformation-classes.html

Here's another blast from the past, an illustration by Madalena for a piece I did a while back for Lab Times about Thelial, a company set up in Lisbon to use drosophila cells for drug screens.
https://madalenaparreira.com/
cc @martinho_lab

#SciArt #ScienceArt #illustration #ScientificIllustration

@martinho_lab @miguelgf That was not so much the low hanging as it was the rotting on the floor fruit, Rui.

I can try with a current immunological one, also vaguely fruity: Original Sin & perhaps prod a reaction out of @victoralab

"One of the most difficult impulses for scientists to curb is the tendency to use specialized language that no one else understands. Every scientific facility I’ve worked in has had its own specific vocabulary, and every scientist has had their own inscrutable, hyperspecific terms for aspects of their project."

https://www.science.org/content/article/new-science-jargon-new-year?utm_campaign=SciMag&utm_medium=ownedSocial&utm_source=LinkedIn

"In this Review, we discuss the origin, heterogeneity, phenotypes, and functional plasticity of TAMs in GBM. Moreover, we pinpoint the aspects of emerging single-cell technologies to identify new TAM subpopulations, which might play a critical role in GBM progression and immunosuppression. Finally, we discuss the current TAM-targeted therapeutic potential in GBM."

#Glioblastoma #TumorAssociatedMacrophage #immunology #immunotherapy

https://www.jci.org/articles/view/163446

'He no ha dado detalles sobre sus experimentos con los embriones ni publicado un estudio detallado sobre el mismo. Un borrador de su estudio desvelado en 2019 por Technology Review mostraba que la edición genética de los embriones había sido imperfecta y que al menos una de las niñas llevaba en su genoma errores no deseados.'

https://elpais.com/ciencia/2023-01-11/el-creador-de-los-primeros-bebes-modificados-geneticamente-vuelve-a-la-ciencia-tras-salir-de-la-carcel-hice-las-cosas-demasiado-rapido.html