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"That's a long-winded way of explaining how I got from working on stress to being interested in the microbiome. The next 10 years were focused on taking advantage of advances in technologies, genetics and sequencing to parse the relationship between the microbiome and the brain and, more recently, on asking if we can translate it to humans"
- John Cryan

febs.onlinelibrary.wiley.com/d

Michele De Luca at University of Modena and Reggio Emilia and Giulio Cossu at Division of Cell Matrix Biology, Regenerative Medicine University of Manchester on cost and availability of advanced gene and cellular therapies (ATMPs).

Due to their high costs and low patient population measures are needed to prevent their withdrawal from the market.

Read more here:
embopress.org/doi/full/10.1525

RT @SalliePermar
“They’ve been almost forgotten.”
TY @nytimes for highlighting disparities in global #HIV treatment/prevention for children: as grown ups, it is our duty to change this trend with research, implementation to reduce infections, make similar gains to adults nytimes.com/2023/01/17/health/

#IIDMastodon Curious about #COVID19 #SARSCoV2 therapeutic antibodies, bivalent vaccines & immune imprinting? Here is our latest work on these topics in collaboration with @DavideCorti6 @msdiamondlab
Led by @AminAddetia @LucaPiccoli9 Brett Case @YoungjunPark11 🧵by @veeslerlab
twitter.com/veeslerlab/status/

RT @CharlesMBrenner@twitter.com

interesting study showing that ancient rockfish were almost certainly long-lived & that they changed genes in insulin signaling & flavonoid metabolism as they diverged to species w _shorter lifespans_

striking evidence that shorter lifespans are adaptive for many rockfish twitter.com/sciencemagazine/st

🐦🔗: twitter.com/CharlesMBrenner/st

RT @SchubelerLab
Two openings at FMI for groupleaders (tenure-track). Great opportunity at a vibrant and interactive institute, highly supportive environment and fantastic location. Reach out if you need more information. twitter.com/FMIscience/status/

The Twitter API lockout of third-party apps is only the latest reminder of centralization's most important rule: The platform owner has the right to capriciously wreck the businesses of people who accepted the platform's invitation to run a business on the platform.

Mammals can create heat with their muscles. A study investigates the evolution of this ability, focusing on the loss of the calcium-sensitive ryanodine receptor (RyR). In PNAS: pnas.org/doi/10.1073/pnas.2117

Harvard Medical School refuses to play a metrics game completely stacked in its favour. I'm actually impressed. I hope more follow suit. It's all a farce. hms.harvard.edu/news/hms-withd

RT @RameshVetukuri
We have an exciting postdoc opportunity in my group to work on cross-kingdom RNAi, if you interested apply by following the link below:
Postdoctoral position on Small-RNAs role in Plant-microbe interactions
slu.se/en/about-slu/work-at-sl
Ref SLU.ua.2023.2.5.1-161

'A century ago, the discovery of hafnium confirmed the validity of the periodic table — but only thanks to scientists who stood up for evidence at a time of global turmoil.'

nature.com/articles/d41586-023

#ChemiVerse #ChemToots #PeriodicTable

Producer Val Lewton is one of the most important figures in horror film history, but is, unfortunately, only really discussed today by filmmakers and cinephiles. This sequence from CAT PEOPLE is a MasterClasses in how to create tension and terror onscreen, a carefully orchestrated attack on the senses common in his films.

Watch: youtube.com/watch?v=lz98akbX_N

#film #movies #cinema #filmmaking #horror #horrorfilm #ValLewton #classicfilms #storytelling

"Microbiolatry".
Spoiler alert: Pasteur won the bet.

From Wasik & Murpy's book on the history of rabies, the aptly named "Rabid".

Amidst all the current discussions around AI, I keep coming back to Joseph Weizenbaum’s comment from 1976: “There are certain tasks which computers ought not be made to do, independent of whether computers can be made to do them.”

"The Friedrich Miescher Institute for Biomedical Research (FMI) invites applications for a tenure-track group leader position (assistant professor level) in Multicellular Systems."

fmi.ch/education-careers/posit

Preprint review should form part of PhD programmes and postdoc training.

"Peer review is an opportunity to demonstrate transferable skills, but most of the institutions that grant PhDs don’t train people in peer review."

nature.com/articles/d41586-023

'What I’d heard of a little Brazilian town on the eastern edge of the Amazon had prepared me for the worst. Criminality plagues many areas of Brazil, and the government’s presence remains feeble in the interior of the country. But even by that measure, the pace of homicides in the region is staggering. “It’s a risky town for a reporter,” said Danicley de Aguiar, a Greenpeace activist.'

nytimes.com/2023/01/17/opinion

"Almost two-thirds of sharks and rays that live around the world’s coral reefs are threatened with extinction with potentially dire knock-on effects for ecosystems and coastal communities, according to new research."

theguardian.com/environment/20

"Here, we review how nutrient acquisition through plasma membrane transporters and engulfment pathways control tumor-associated macrophage differentiation and function. We also discuss how nutrient metabolism regulates tumor-associated macrophages and how these processes may be targeted for cancer therapy."
@ImmunityCP

cell.com/immunity/fulltext/S10

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