Harvest in Bourgogne (France 1963). Vendemmia in Borgogna (Francia 1963). Photo: Hans Silvester. #BlackAndWhitePhotography
Exciting new paper in @PLOSBiology — we show that plasmids use translational global regulators to rewire host cells including expression of key ecological traits, like metabolism and motility, whilst also boosting horizontal transmission of the plasmid
This was a big collaborative effort with colleagues at John Innes Centre, Birmingham, Sheffield & Liverpool
#plasmid #HGT #MobileGeneticElements
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001988
When it gets hot, Polycomb comes to the rescue... "Warm temperature-triggered developmental reprogramming requires VIL1-mediated genome-wide H3K27me3 accumulation in Arabidopsis" https://journals.biologists.com/dev/article-abstract/doi/10.1242/dev.201343/286988/Warm-temperature-triggered-developmental/
'A team of Israeli contractors who claim to have manipulated more than 30 elections around the world using hacking, sabotage and automated disinformation on social media has been exposed in a new investigation.'
"Early studies of iron-binding proteins in insects suggested that insects and mammals have surprisingly different mechanisms of iron homeostasis, including different primary mechanisms for exporting iron from cells and for transporting iron from one cell to another, and subsequent studies have continued to support this view."
https://www.annualreviews.org/doi/abs/10.1146/annurev-ento-040622-092836
After seeing pretty compelling evidence that #musk is forcing you to see his illuminated thoughts either you like it or not (and #Twitter engineers to tweak the system to do so), I am really wondering why is anyone still interested in a platform that so obviously feeds you what *he* wants you to see... #scaryshit
@RWerpachowski@mastodon.green This one is an oldie but a goldie. I hate powerpoint with the fire of a thousand suns.
Fine, maybe not *all*
“It would be foolish to blame consultancies for all the problems that advanced capitalism has created,” state Mariana Mazzucato and Rosie Collington in their conclusion. Nevertheless, the authors of The Big Con blame consultancies for an awful lot, starting with: “The pristine PowerPoints, copy-and-pasted formulas for strategy and often ineffective tools that many consultancies employ.”
https://www.ft.com/content/ae2a6f5a-68e9-43a1-b313-1664c91e0287
Amazing work, @VikiLovesFACS. So well deserved.
---
RT @ClareCollege
Viki Male (2004) returned to college to receive the alumna of the year award - set up to recognise individual contributions to society.
During the pandemic, Viki ensured pregnant people could access evidence-based information on the COVID vaccine.
http://bit.ly/3K6GWxG
https://twitter.com/ClareCollege/status/1625547468598394883
@Hatty @bioRxiv_microbio I had not, thank you.
Congrats to all the newly elected American Academy of #Microbiology fellows - tagging a few I know are on Mastodon @drdrandrews @jenbiddle @chicaScientifica @florian_krammer https://asm.org/Press-Releases/2023/February/65-Fellows-Elected-into-the-American-Academy-of-Mi?_zs=lekpl&_zl=3BRR2
'Chinese pharmaceutical group CanSino Biologics said demand for its Covid-19 vaccine was “dying down” in China after the abrupt end of the country’s tough zero-Covid policies, underscoring the challenges facing the sector in the largest remaining under-vaccinated market'
https://www.ft.com/content/b201dc98-2187-43de-817a-c9a3d0d981b9
My latest Clinical Pipeline column for #NatureMedicine is out today, a look at Moderna's RNA vaccine for RSV & a survey of what's, well, in the pipeline, for RSV immunotherapies, including vaccines and monoclonals.
#Vaccine #drugdiscovery #drugdevelopment #mRNA #RSV #immunology #MonoclonalAntibody
February 15, 1819, birthday of French scientist and author Louis #Figuier. His 1864 textbook "La Terre avant le déluge" inspired Jules #Verne's famous novel "Journey To The Center of the #Earth" 🌍
http://bressan-geoconsult.eu/the-geology-of-jules-vernes-journey-to-the-center-of-the-earth/
Plasmids manipulate host cells to their benefit. @Catriona1392 @BrockhurstLab &co describe a #plasmid-borne translational regulator that subverts ecological traits in #bacteria, inducing community organization & promoting plasmid transmission #PLOSBiology https://plos.io/3I4NES6
"The area of sea ice around Antarctica has hit a record low, with scientists reporting “never having seen such an extreme situation before”. The ice extent is expected to shrink even further before this year’s summer melting season ends."
https://www.theguardian.com/world/2023/feb/15/antarctic-sea-ice-hits-record-low-climate-crisis
CIML is recruiting new PIs
"The CIML aims at recruiting up to two team leaders.
We are looking for outstanding candidates on a mission to advance knowledge on all aspects of immunology. Applicants should send a CV with a list of publications, a 2-page summary of past research achievements and future projects, and contact information for three referees, before June 30th to Dr. Marc Dalod, to whom informal inquiries may also be adressed."
http://www.ciml.univ-mrs.fr/call-ciml-group-leader-positions-2023
#IDMastodon @jama_current InThis #ClinicalInvestigation with 825 patients (75.4% of #COVID19 survivors experienced cardiopulmonary problems at 6 mth ) symptoms, disabilities, financial problems remain highly prevalent with some new problems in mths from post covid (#LongCovid )
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2801413?utm_source=twitter&utm_campaign=content-shareicons&utm_content=article_engagement&utm_medium=social&utm_term=021523#.Y-yPRIihwWo.twitter
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com