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Blood Vessel Organoids for Development & Disease

Self-organizing capillary blood vessel + (+Astrocyte for )

Transplant to gain vascular hierarchy

Organotypism Through Genetic Drivers

Dr. Josef Penninger lab Circ Res 2023
ahajournals.org/doi/10.1161/CI

Saint in Pamplona realizes what happened to Jake Barnes in "The Sun Also Rises"

#Immunology #cellimmunity @PLOSBiology LRRC15 is not a #SarsCoV2 entry receptor but can suppress spike-mediated entry . LRRC15 is also expressed in fibroblast cells, the cells that control lung fibrosis, a disease which causes damaged and scarred lung tissue. #COVID19 can lead to lung fibrosis, and the finding may have implications for #LongCovid.
📌journals.plos.org/plosbiology/
📌 journals.plos.org/plosbiology/

#OtD 20 Feb 1988 20k people in Manchester marched against Margaret Thatcher's homophobic section 28 law, which made it illegal for public bodies to "promote" homosexuality, including teaching its "acceptability" in school

Notch signaling in development and homeostasis

In their 'Development at a glance' article and poster, Oren Gozlan and David Sprinzak provide a brief overview of the Notch signaling and function in development and homeostasis

journals.biologists.com/dev/ar

This is *not* the way scientific papers typically begin:
_________________________

We are running out of time. Ecosystems across the planet are being destroyed at an accelerating rate. The life sciences – once a field dedicated to the study of living systems and our interactions with them – are increasingly becoming sciences of the dead. Up to one million species are currently threatened with extinction, many of them within decades.
_________________________

It's a very good sign, however, an indication that at least some scientists are now ready to speak boldly and unequivocally about the greatest emergency our species has ever faced.

SEE THE FULL PAPER -- elifesciences.org/articles/832

#ClimateEmergency #BiodiversityLoss #Extinction

"El laboratorio de David Baker en la Universidad de Washington (Estados Unidos) va un paso más allá. Ha desarrollado varios sistemas de inteligencia artificial abiertos que crean proteínas que nunca han existido en la naturaleza."

elpais.com/ciencia/2023-02-19/

Le Floc’h et al at Regeneron generated an anti-common gamma chain monoclonal that blocks signaling.

"Treatment of nonhuman primates with REGN7257 suppressed NK cells and T cells without affecting granulocytes, erythrocytes, or platelets."

science.org/doi/10.1126/scitra

RT @sivajothy
The call for symposia at ICE (The International Congress of Entomology) in Kyoto 2024 is now open. ( shorturl.at/cxyA8 ). please retweet.

📢 Don't miss: Tuuli Lappalainen @tuuliel_lab (@nygenome @KTHuniversity @scilifelab) will speak at our #DahlemColloquium!

📜 Functional variation in the human #genome: lessons from the #transcriptome
📆 27. FEB, 11:00 AM (CET)
📍 @MPI_MolGen, #Berlin
🔗 molgen.mpg.de/events/33625/396

Deadline for applications to the Summer internship for INdigenous peoples in Genomics (SING) workshop to be held this year together with Diné College and Northern Arizona University is extended to February 28.

Apply here: singconsortium.org/

#NativesInSTEM #IndigenousSTEM #IndigenousScience #IndigenizeSTEM

MDPI's IJMS just sent me an email just to say they published a paper and I could read it if I wanted to. Heck, if I wanted to submit an article, they'd be pleased as punch.

I wasn't a reviewer. I had no involvement at any point. This is just spam. Specifically, it's "rent-seeking" behaviour from a publishing group nearly everyone deems "predatory."

See: bit.ly/1yrPredPub

#MDPI #PredatoryPublisher #AcademicChatter

Some objects you have to share immediately after seeing it: a Roman flask in the shape of a fish.
We don't know what flaks in the shape fishes were used for, maybe the shape relates to the content (garum/fish sauce), maybe it was used to hold oil.

On display at Pierides Museum, Larnaka, Cyprus.

Photo: Jeff Amadon via Flickr

#RomanArchaeology

Structural basis for binding of Smaug to the GPCR Smoothened and to the germline inducer Oskar

Smaug no longer desolate thanks to #StructuralBiology
#crystallography @strucbio #Science #Research

biorxiv.org/cgi/content/short/

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