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Variants & MISC

"Across all the variant periods, the risk of ventricular dysfunction was highest among the patients hospitalized during the alpha+ period as compared with those during the ancestral period (35% vs. 28%, relative risk, 1.19; 95% confidence interval, 1.04 to 1.35)."

nejm.org/doi/full/10.1056/NEJM

RT @Anne_On_Tw
I am looking to recruit a postdoc for my lab @ccnlab at UC Berkeley ccn.berkeley.edu. This is an NIH funded position, for a methods oriented project - we are looking for applicants with strong quantitative skills. Please forward to potential applicants!

"With IL-8-humanized mouse strain, we demonstrate that IL-8-producing CD4+ T, myeloid, and tumor cells orchestrate myeloid-derived suppressor cell infiltration and angiogenesis, which results in enhanced tumor growth but reduced ICB efficacy."

cell.com/cancer-cell/fulltext/

"The particles in pigments are bulky and difficult for an immune cell’s enzymes to degrade. So when inks get gulped down by immune cells such as skin-dwelling macrophages—which spend their lives devouring pathogens, cellular debris, and other schmutz within just a teeny patch of flesh—it can transform into a microscopic version of gum. The pigment particles lodge themselves inside macrophages’ innards, refusing to be broken down. When ink is visible at the surface of the body, it’s not just interlaced among skin cells—it’s shining out from the bellies of macrophages that can’t digest it."

theatlantic.com/science/archiv

RT @SGribaldo
Faculty position in Microbiology. Great opportunity in beautiful Marseille, France 👇 twitter.com/lcb_officiel/statu

MDPI's flagship journal IJERPH just got de-listed by Web of Science/Clarivate! WOW! 🤯

This is huge news. IJERPH is 2nd only to Scientific Reports in terms of total article output. IJERPH no longer has an impact factor, no longer in Web of Science.

Will pen a quick post in a bit, but for now, see Paolo Crosetto's thread on birdsite: twitter.com/PaoloCrosetto/stat

"the very fact that we need a central, private, for-profit authority and we all live by their word is compete madness on our part."

"For this work and other efforts to try to curb the spread of H.I.V. in the Nashville region, Ms. Binkley and her colleagues have relied heavily on federal grant money. So they were stunned when Tennessee’s health commissioner announced earlier this year that the state would no longer accept $8.8 million in federal grant money, which for more than a decade has been distributed among nonprofit groups, county health departments and health care organizations."


cc @gregggonsalves

nytimes.com/2023/03/24/us/tenn

RT @HHMIJanelia
📢 We’re #hiring!

Our Computation & Theory research area is recruiting early-career scientists in 🧮 mathematics, ⚛️ physics, 💻 computer science, and ⚙️ engineering to join our Theory Fellow program.

🔗 Learn more & apply by May 2 ▶️ janelia.org/our-research/overv

When a fish beats its tail, it produces vortices in the water that other fish could take advantage of to save energy while swimming. ​​elifesciences.org/articles/868

Pff... wake me up when @kevinng & @victoralab have sequence Beethoven's germinal centers - it may reveal the biological roots of the light zone/dark zone motif opening the 5th.

RT @rulandsgroup
New preprint: complex systems tend to be stable if interactions between components are sufficiently homogeneous. We show that key features of biol. systems, non-local interactions and intrinsic noise, destabilize them and facilitate pattern formation arxiv.org/abs/2303.12611

'Doadrio, de 64 años, entró al museo de voluntario cuando tenía 18, para organizar los miles de botes con peces, poco después de la muerte del dictador Francisco Franco. “Había colecciones abandonadas desde 1936, llenas de moho, con las ratas por los pasillos. El museo ha cambiado radicalmente desde que entré”, celebra el biólogo.'

elpais.com/ciencia/2023-03-23/

"I'm a fan of phenotypic assays in general - the idea of letting the cells tell me what's going on is more appealing than me trying to tell them (they don't listen very well). But that said, a bad phenotypic assay is truly the worst of both worlds."

science.org/content/blog-post/

FT's @KuperSimon: "If we’re serious about keeping the planet liveable, we have to regulate & tax huge cars out of existence." #SUVs are: "not only awful for the climate, they’re also killing pedestrians, including children in driveways" ft.com/content/7612e3c0-0e10-4

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