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'In his 20s, at the request of a gambling acquaintance who couldn’t break a losing run at dice, he undertook groundbreaking studies in probability theory. Before that, he invented the world’s first mechanical calculator – the snazzily named Pascaline.'

theguardian.com/commentisfree/

This sounds cool and promising: ‘Klotho itself cannot cross the barrier from blood to brain’, so this memory improvement might be a general improvement in ageing that shows up in brain function? nature.com/articles/d41586-023

#aging #ageing #agingbiology #ageingbiology

Testing the #academia outreach here on Mastodon. Please boost if you think you know others who might know.

I'm looking for some good light undergraduate-level books/articles in English about Taiwan under the Japanese and during the White Terror. History, culture, I would even love recommendations of short fiction if you have any.

Thanks

#Taiwan #Colonialism #WhiteTerror #JapaneseColonialism #History #CulturalStudies #Literature

@thelancet ‘Opioids should not be recommended for acute non-specific low back pain or neck pain given that we found no significant difference in pain severity compared with placebo. This finding calls for a change in the frequent use of opioids for these conditions’
thelancet.com/journals/lancet/

📖 #MondayMusings with @PeerCommunityIn 📖

"The relationship between impact metrics and #APCs evidences that publishers fix fees 𝐝𝐞𝐩𝐞𝐧𝐝𝐢𝐧𝐠 𝐨𝐧 𝐭𝐡𝐞 𝐫𝐞𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧 𝐚𝐬𝐬𝐢𝐠𝐧𝐞𝐝 to journals by peers"
#ScholarlyCommunication

#Science is funded by public money.

We need new #ScholarlyCommunication models like PCI or diamond #OpenAccess journals to give money back to research and promote #ResearchIntegrity #OpenEdu #OpenScience #AcademicTwitter

onlinelibrary.wiley.com/doi/10

If you gain biological insight from #microscopy images, then check out the ‘Beyond pretty pictures’ subgroup at #CellBio2023, with tandem talks highlighting collaborative research between experimental & computational biologists.
Abstract deadline: 1 August
focalplane.biologists.com/2023
#CellBiology #bioimageanalysis #conference

What doesn’t kill you makes you younger: damage-induced tissue regeneration resets the clock for elderly flatworms. 👩‍🎤🎵

Really entertaining preLight prepared by Sophia Friesen covering work from the #GuoLonghua Lab #UMich. #preprint

#development #physiology #ageing

#preLight 👉 prelights.biologists.com/highl

In Japanese folklore kaze no kami are invisible, evil spirits believed to cause sickness and suffering by travelling on, and controlling, the wind. When they encounter humans, they exhale toxic clouds of yellow breath, causing all who breathe it in to become ill. Despite this, these spirits were sometimes enshrined as gods by those whose livelihoods depended upon favourable winds.
#MythologyMonday #yokai #mythology #JapaneseFolklore #JapaneseArt #ukiyoe @mythology @folklore
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SIB Swiss Institute of Bioinformatics - Comparative Genomics Course 2023
sib.swiss/training/course/2023
The aims of this course are to (i) explore key evolutionary concepts, (ii) examine different methodological approaches, and (iii) gain hands-on experience in eukaryotic comparative genomic analyses.
Application deadline:
26 July 2023

Gut #microbiota regulates blood-#cerebrospinal fluid barrier function and Aβ pathology
Roos Vandenbroucke and colleagues
The gut microbiota promotes blood-cerebrospinal fluid (#CSF) barrier integrity by regulating the subcellular localization of tight junctions and reduces #Alzheimer's disease pathology
embopress.org/doi/full/10.1525

on day 87 of drawing animals I was tired and completely underestimated how hard giant #Isopods would be to draw for me. I am still a bit confused about it. Might try them again some time when I am more awake, maybe that really _was_ the thing that tripped me up. Still, I did not falter! And still sticking with the marine theme for #Mermay.

#Ink #Art #Invertebrates

Come for the story about how GLP-1 receptor agonists — the hot new diet drugs like Wegovy — were developed. Stay for the cocktail-nicking vervet monkeys & what they tell us about the drugs' addiction curbing capacities. statnews.com/2023/07/10/new-we

'Here, we analyzed subcellular distribution in micropatterned patient-derived melanoma cells and found that lysosome spreading scales with their aggressiveness.'

biorxiv.org/content/10.1101/20

'This proof-of-concept study suggests that bNAbs may represent a promising treatment modality for infants and children living with HIV-1. Future studies using newer bNAb combinations with greater breadth and potency are warranted.'

science.org/doi/10.1126/scitra

With 2024 just around the corner, it's hard to fathom why Democrats aren't pushing this nomination through Congress. @STAT's Sarah Owermohle on the slow roll of the confirmation of NIH director nominee Monica Bertagnolli. statnews.com/2023/07/10/biden-

In rural India, attending treatment for cancer can mean day labourers giving up their pay.

One cancer centre in India is offering free food and accommodation—and even ad hoc employment—in a bid to get to the root of the problem.

@polkajunction reports
bmj.com/content/382/bmj.p1095

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