Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
'Su proyecto de doctorado consistía en visualizar y analizar sus cromosomas, una tarea que implicaba la recolección y preparación de muestras derivadas de los testículos de los machos. Durante este proceso, sin embargo, se enfrentó con un problema curioso: cuando realizaba la disección de algunos topos que reconocía como machos y los analizaba en el laboratorio, resultaban ser genéticamente hembras; es decir, sus cromosomas sexuales eran XX (hembra) y no XY (macho).'
Thiago Carvalho
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FENS/IBRO-PERC Exchange Fellowships Programme
Deadline Oct 15
'Are you based in Europe? Are you looking for the next step in your career? Apply for the FENS/IBRO-PERC Exchange Fellowships and stay for three months in another European lab.'
#neuroscience
https://www.fens.org/careers/grants-and-stipends/grant/fens-ibro-perc-exchange-fellowships
Thiago Carvalho
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Happy Monday again, #ScienceMastodon! The first Research Highlight from JCS Issue 16 features a paper from Toshiyuki Oda and colleagues at the Universities of Yamanashi and Tokyo, using the unicellular algae Chlamydomonas reinhardtii to break down roles of tubulin modifications in ciliary/flagellar motility. #CellBiology #microtubules #flagellates
Roles of ciliary tubulin PTMs in Chlamydomonas reinhardtii
https://journals.biologists.com/jcs/article/136/16/e136_e1601/325932/Roles-of-ciliary-tubulin-PTMs-in-Chlamydomonas
'A better way to understand the EU is an expression of regionalism – which is analogous to nationalism, rather than the opposite of it, as many “pro-Europeans” imagine it to be. Thinking of the EU in terms of regionalism rather than cosmopolitanism also allows us to understand more clearly the tensions within the European project.'
Thiago Carvalho
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Do you think that using the term “evolutionary rate” for the ratio dN/dS is accurate or misleading?
#MolecularEvolution
#EvolutionaryBiology
#Evolution
'Mice provide a great model system for studying the link between thermoregulation and feeding because, when living in a 4 °C environment as opposed to one at room temperature, they can double their food intake'
"The Art of Anatomy in Medieval Europe
Taylor McCall Reaktion (2023)
Art historian Taylor McCall dismantles the common belief that Renaissance figures such as Leonardo da Vinci and Andreas Vesalius founded the field of human anatomy. Assisted by vivid medieval illustrations, she argues that the earliest anatomical images date from the twelfth century, in monasteries and then early universities. Her scholarly book, the first in this field, aims to show that such imagery is “its own visual language”, by exploring anatomy in religious contexts, medical teaching and practice, and the work of professional artists."
Thiago Carvalho
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Now published: Mendes de Farias et al, Lessons learned to boost a bioinformatics knowledge base reusability, the Bgee experience https://academic.oup.com/gigascience/article/doi/10.1093/gigascience/giad058/7243539 #KnowledgeBase #bioinformatics #interoperability #FAIR @GigaScience @wikidata #NCBI #SIB #FAIRdata
Thiago Carvalho
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“One Night Cough Syrup” from the 1930s, which contained cannabis, morphine, chloroform, and alcohol! In 1934, the FDA ruled that the claims of the cough syrup's therapeutic properties were misleading, and remaining stock was destroyed.
Follow me for more medical history content!
#histmed #histsci #histodons #histodon #twitterexodus #twittermigration #medhist #DYK #bigpharma
''Tudo começou em Maio, com uma notícia do El Economista que revelava a intenção da Renfe de entrar no território português no eixo La Coruña-Santiago de Compostela-Vigo-Porto-Lisboa. Depois, em Julho, um comunicado oficial da operadora pública espanhola anunciava um “novo serviço internacional transfronteiriço” entre Plasencia e Évora.'
Thiago Carvalho
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MGR PROTOCOL REVIEW AND MONITORING SYSTEM
Moffitt Cancer Center
See the full job description on jobRxiv: https://jobrxiv.org/job/mgr-protocol-review-and-monitoring-system/?feed_id=56023
#ScienceJobs #hiring #research
Tampa #UnitedStatesUS
https://jobrxiv.org/job/mgr-protocol-review-and-monitoring-system/?feed_id=56023
Thiago Carvalho
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'Hay una falta de escrúpulos en cómo tratan la verdad. Joseph Goebbels, el gran jefe de la propaganda nazi, era un maestro de distorsionarla, pero esto ha ido más allá con los populistas de hoy. En cierto modo, no creen que la verdad como tal exista, y esto es muy preocupante, porque hoy en día tenemos redes sociales, y es así como difunden sus mentiras.'
Thiago Carvalho
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'These results suggest that hyperactivity of both mTORC1 and mTORC2 are sufficient to cause epilepsy, and that targeted therapies should aim to reduce activity of both complexes.'
#Preprint #neuroscience
Thiago Carvalho
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'Moutinho says that, to score a 5, the Lula administration needs to enable more effective surveillance and control of deforestation in all biomes. The government should also act quickly to give a ‘legal status’ to untitled public lands, especially in the Amazon and Cerrado'
Thiago Carvalho
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"Within the confines of the traditional clinical research model, studying novel treatments for rare cancer subtypes is challenging — particularly with respect to patient engagement, financial burden and timeliness. In this issue of Nature Medicine, Liu et al. describe a novel trial design that positions the patient at the focal point of clinical investigation, while exploring the safety and efficacy of first-line pyrotinib in patients with metastatic HER2+ NSCLC"
Thiago Carvalho
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"Let this great maxim be my virtue’s guide,—
In part she is to blame that has been tried:
He comes too near that comes to be denied."
The Lady’s Resolve
Lady Mary Wortley Montagu died #OTD in 1762. She is today chiefly remembered for her Turkish Embassy Letters describing her travels to the Ottoman Empire. In addition, she is also known for introducing and advocating for smallpox inoculation to Britain after her return from Turkey. via @wikipedia
Thiago Carvalho
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"Models taken from ‘Stanley Kubrick’s The Shining’, published by Taschen"
https://www.ft.com/content/a9949d9d-08be-4de9-b3a4-f51403d8546b
Thiago Carvalho
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Meanwhile, in Portugal, one cant go to Madrid by train anymore & all the ruling parties debate is where to put a new airport.
"The Italian state-owned train operator is aiming to launch high-speed rail services between some of Europe’s biggest cities as it takes advantage of the liberalisation of the region’s network."
https://www.ft.com/content/7ccb3037-64f8-45f1-9368-cdc09bd33362
Thiago Carvalho
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'Stuff aggregates. That's a lesson in drug screening for you in two words! The problem is that lot of the things that we would like to put into solution to run assays doesn't really want to be in solution all that much.'
https://www.science.org/content/blog-post/breaking-aggregates-peg
Thiago Carvalho
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Hey #cilia & #centrosome peeps, registration is now open for our in-person 🎇 UK Cilia Network Fall meeting🎇 in Edinburgh Friday October 6th, 2023! Our keynote will be from Prof Dagmar Wachten (Bonn, DE) 'Shedding light on ciliary signaling and function'. Lots of talk slots and posters spots too- join us!
Please register: https://forms.office.com/e/EtTDAeGaFY. Deadline for talk and poster consideration is 04/09/2023 17:00.
Boosts welcome!
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
