'I suddenly remembered a patient on the Neurology Wards 15 years before, who had woken from sleep, one Christmas Day, to find ‘a strange leg’ in his bed. There was a Christmas party going on, and the only ‘explanation’ he could imagine was that one of the nurses, as a joke, had filched a leg from the Anatomy Room, and slipped it under the covers as he slept.'
- Oliver Sacks @lrb
https://www.lrb.co.uk/the-paper/v04/n11/oliver-sacks/the-leg
🆕#blogpost: Daniela Mera-Rodríguez & colleagues explore the evolution of eusocial insects: They investigate the historical biogeography & transitions from colony life to social parasitism in the ant genus Myrmecia.
Pic: CC-BY-NC-ND doi.org/10.1016/j.ympev.2023.107825
https://blog.myrmecologicalnews.org/2023/08/24/biogeography-and-evolution-of-social-parasitism-in-bulldog-ants/
'These data support the potential use of IGF1 in combination with common γ-chain cytokines to drive homeostatic T cell expansion, both in vitro and in vivo, for cellular therapeutics and ex vivo gene editing.'
#immunology
On the Decoupling of Evolutionary Changes in mRNA and Protein Levels https://doi.org/10.1093/molbev/msad169 #science #evolution #biology #genome #evolgen_paper
Whole Genome Duplication and Gene Evolution in the Hyperdiverse Venomous Gastropods https://doi.org/10.1093/molbev/msad171 #science #evolution #biology #genome #evolgen_paper
📢 Nominations now open for the Lifetime Achievement Award! 🏆
Whose conceptual advances, impactful publications, outreach & education efforts, mentorship & training, service to the community, or diversity & inclusion work has contributed to the field & community?
Nominate them for this award! We also welcome self nominations!
The initial nomination form requires just two 250-word statements, with longer letters of support requested later.
Deadline: September 30
http://www.evolutionsociety.org/society-awards-and-prizes/lifetime-achievement-award.html
Another US university thinks it's a good idea to abolish proper language classes, and will "replace" them with apps … Please read about it and perhaps sign the petition here:
https://www.change.org/p/preserve-students-rights-to-study-world-languages-at-wvu
@academicchatter
@academicsunite
'Looking back, it can feel as if Newton were destined from birth to revolutionise the cosmos, but for many of his contemporaries he was an eccentric academic with a foul temper.'
https://www.historytoday.com/archive/great-debates/glory-or-gravity
New study suggests people who tested negative for Covid-19 can still develop long Covid
"The Art of Anatomy in Medieval Europe
Taylor McCall Reaktion (2023)
Art historian Taylor McCall dismantles the common belief that Renaissance figures such as Leonardo da Vinci and Andreas Vesalius founded the field of human anatomy. Assisted by vivid medieval illustrations, she argues that the earliest anatomical images date from the twelfth century, in monasteries and then early universities. Her scholarly book, the first in this field, aims to show that such imagery is “its own visual language”, by exploring anatomy in religious contexts, medical teaching and practice, and the work of professional artists."
'La campaña de vacunación frente a la covid comenzará en otoño junto con la de la gripe, enfocada a los colectivos más vulnerables a la enfermedad. Pero todavía no está claro qué fármacos se utilizarán.'
"An influential expert panel has given its highest recommendation to an expanded menu of H.I.V. prevention strategies for adults and adolescents, a move that will require private insurers to cover the drugs without a co-pay or deductible under the Affordable Care Act."
#HIV #publichealth
'Meanwhile, scientific interest in vagus nerve stimulation is exploding, with studies investigating it as a potential treatment for everything from obesity to depression, arthritis and Covid-related fatigue. So, what exactly is the vagus nerve, and is all this hype warranted?'
'The elucidation of the lipid metabolic pathways that promote innate immune memory contributes to our understanding of trained immunity and may help identify therapeutic tools and targets for the modulation of innate immune responses.'
#immunology #InnateImmunity #Preprint
"On Tuesday, an international team announced in the journal Cell that they had identified a potential new antibiotic lurking unnoticed in the sandy soil of North Carolina. The compound, called clovibactin, employs an unusual method of killing bacteria that makes it tough for targets to develop resistance. While clinical trials in humans are several years away, the finding is a glimmer of hope in an increasingly drug-resistant world."
#microbiology #antibioticresistance #antibiotics #drugdevelopment
https://www.ft.com/content/a8d62524-3f3f-4d61-a27f-a689a13f9232
Interesting work from the labs of David Baker and Carolyn Bertozzi showing EndoTag proteins, designed to bind extracellular face of receptors, target complexes for degradation.
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation and amplify signaling
https://www.biorxiv.org/content/10.1101/2023.08.19.553321v1
Turtle Shells Record Nuclear History https://www.scientificamerican.com/article/turtle-shells-record-nuclear-history/
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com