Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
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V2 of my preprint with PhD student Kim Verity is now online: https://www.biorxiv.org/content/10.1101/2023.07.17.549219v2
tldr: If you want to assess the shape (e.g. balance, diversity) of a rooted tree then generally you're better off using our new indices than Sackin's index, phylogenetic entropy, etc.
The article is long mainly because we provide lots of examples. I plan soon to write a shorter #mathonco blog post explaining why these indices are better than prior approaches. Meanwhile, here's a poster.
Checkpoint inhibitors beyond cancer: targets for restoring CD8 T cell function in people living with HIV.
"Our results demonstrated a marked and significant increase in TIGIT CD8+ T-cells, particularly within the central memory compartment, not ameliorated by long-term ART."
Thiago Carvalho
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Out @PLOSBiology! Inhibitory signals from turning neurons gate the worm's response to mechanosensory stimuli! Beautiful work by Sandeep Kumar and co-authors Anuj Sharma, Andrew Tran & Mochi Liu https://plos.io/455hWOh
Thiago Carvalho
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Senior Researcher in Flow Cytometry and Cell Sorting Core
St. Jude Children's Research Hospital
See the full job description on jobRxiv: https://jobrxiv.org/job/senior-researcher-in-flow-cytometry-and-cell-sorting-core/?feed_id=59556
#ScienceJobs #hiring #research
Memphis #UnitedStatesUS #Researcher
https://jobrxiv.org/job/senior-researcher-in-flow-cytometry-and-cell-sorting-core/?feed_id=59556
Thiago Carvalho
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This “thought-provoking” paper exploits new #CryoET tools to examine the state of chromatin in situ, finding that nucleosomes in baker’s yeast cells are different from those in test tubes. https://elifesciences.org/articles/87672?utm_source=mastodon&utm_medium=social&utm_campaign=organic
'Their personalities were fundamentally unalike, in ways that could scratch like sandpaper. The Irish critic George Moore, who hung out with them in Paris, described them thus: “Manet loud, declaratory, and eager for medals and decorations; Degas sharp, deep, more profound, scornfully sarcastic.”
https://www.nytimes.com/2023/09/21/arts/design/manet-degas-met-museum.html
Thiago Carvalho
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Marine Le Pen should stand trial over alleged misuse of EU funds, say prosecutors
Request comes after a seven-year investigation into far-right leader’s party
Thiago Carvalho
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On this day in 1863: Alexandre Yersin born, co-discovered bacteria that causes the plague (Yersina pestis) & diphtheria toxin #ThisDayInBiotech
Thiago Carvalho
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'Internal models of self-motion: neural computations by the vestibular cerebellum'
by Kathleen E. Cullen
https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(23)00207-2
'El teniente coronel brasileño Mauro Cid, que durante cuatro años fue secretario particular de Jair Bolsonaro, ha declarado a la policía que, tras la derrota electoral, el aún presidente se reunió con la cúpula militar para consultarles sobre un posible golpe de Estado'
Thiago Carvalho
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Michael Faraday was born #OTD in 1791. English scientist who contributed to the study of electromagnetism and electrochemistry. His main discoveries include the principles underlying electromagnetic induction, diamagnetism and electrolysis. As a chemist, he discovered benzene, investigated the clathrate hydrate of chlorine, invented an early form of the Bunsen burner and the system of oxidation numbers. via @wikipedia
Michael Faraday at PG:
https://www.gutenberg.org/ebooks/author/5541
Thiago Carvalho
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'Because the scRNA-seq dataset had been obtained using CITE-seq, a method that keeps track of cell-surface markers by using oligonucleotide-tagged antibodies, we were able to identify surface markers for human exTreg cells. We found that CD56 and CD16 (normally expressed by natural killer cells) identify human exTreg cells.'
Thiago Carvalho
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I talked to Inside Science on BBC Radio Four about our upcoming ocean-based carbon dioxide removal (#CDR) experiment in San Francisco Bay here. I also said other things about CDR and MRV. Starts at 21:45.
"(...) in 2022, the College Board boasts, roughly 1.2 million students took more than four million A.P. exams in public high schools throughout the country. And when I teach a first-year writing course, or an introductory course in the English major, I inevitably spend the first few weeks undoing the damage the A.P. system does to how students understand both writing and the study of literature."
https://newrepublic.com/article/173547/ap-classes-waste-time-annie-abrams-education-book-review
Thiago Carvalho
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Chromosome-Scale Genome Assembly of the Solitary Parasitoid Wasp Microplitis manilae Ashmead, 1904 (Braconidae: Microgastrinae) https://doi.org/10.1093/gbe/evad144 #science #evolution #biology #genome #evolgen_paper
Thiago Carvalho
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.@xanderjones82 &co describe Highlighter, an #optogenetic tool for fine-scale eukaryotic #GeneExpression control, and deploy it in #plants to enable cell-level hypothesis testing. @slcuplants @RobertoHofmann1 #PLOSBiology https://plos.io/3RvZvzh
Thiago Carvalho
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#LongCovid: the doctors’ lives destroyed by an illness they caught while doing their jobs
'For German contemporaries, the leitmotif of 1923 was uncertainty. At different times the country seemed on the brink of civil war, communist revolution, military dictatorship, societal implosion, or a combination of the above. As the academic Victor Klemperer noted in his diary: “Every day you say that a catastrophe must arrive, without knowing which one”.'
https://www.ft.com/content/67aeb1f8-060e-47f5-b341-50373327972f
Thiago Carvalho
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Canonical #glycolysis converts glucose into 2x #acetylCoA via eleven biochemical reactions. This study repurposes #phosphoketolase to construct an artificial three-reaction pathway with a theoretical 100% yield of acetyl-CoA from any sugar. #SynBio #PLOSBiology https://plos.io/48sKTH0
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
