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Metabolic constraints on growth explain how developmental temperature scales synaptic connectivity relevant for behaviour. biorxiv.org/content/10.1101/20

Booooo

"QI has located no evidence for the existence of this quotation in the 1860s, 1870s, or 1880s. The earliest citation known to QI appeared in an 1893 text titled “Verbum Dei: The Yale Lectures on Preaching”"

quoteinvestigator.com/2011/02/

"This series of prints was created between 2017 & 2021.It consists of several aquatints of stages, doors, caves or forests, where figures have been inserted through the technique of chine-collé, and colours added through viscosity printing. "

madalenaparreira.com/Aquatints

The wrong end?

"We now call them B cells, the B standing for bursa of Fabricius. This is an organ, situated at the wrong end of birds, that mammals lack: we produce B cells from our bone marrow."

lrb.co.uk/blog/2023/october/bu

"While the prevailing theory was that small particles, called fomites, where responsible for the spread of yellow fever, another theory proposed that mosquitoes carrying a particular pathogen were responsible for the disease. Reed’s task was to determine, once and for all, what exactly caused yellow fever."

aeon.co/essays/should-we-celeb

Journal #authorship practices have not sufficiently evolved to reflect how research is done.

In this #PLOSBiology Perspective, Veronique Kiermer argues for urgent improvements to support teams, collaboration, and #openscience.

#publishing #AcademicChatter

plos.io/3QgSwJs

Science in Portugal never recovered from the Troika. According this piece in Expresso (a credible newspaper) public investment has now regressed to 1991 levels.

"Os números são inequívocos: se em 2010 a despesa pública em investigação e desenvolvimento chegou a 0,54% do PIB, em 2023 não ultrapassa os 0,32% — um valor inferior ao registado em 1991 e que representa menos de metade da média atual da OCDE."

expresso.pt/orcamento-do-estad?

Quoi?

"In summary, defined effective anticancer activity of human effector CD8+ T cells with an exhausted-like phenotype, supporting clinical exploration of such cells in adoptive T cell therapies."

biorxiv.org/content/10.1101/20

"Their core finding is that eliminating adrenoceptor β1 (ADRB1) from T cells, or globally blocking ADRB1 with beta-blockers, enhances the capacity of T cells to secrete effector molecules and cytokines and increases effector capacity in chronic infections and tumors."

nature.com/articles/s41590-023

(Image: Hokyoung Kim)
"Fire is a natural phenomenon; some species actually benefit from its effects and even those that don’t can be remarkably resilient in the face of flames. But as fires intensify, they are beginning to outstrip nature’s ability to bounce back. “Not all fires have the same impact,” said Morgan Tingley, an ecologist at the University of California, Los Angeles. “These megafires are not good for ecosystems.”'

nytimes.com/2023/10/15/science

Effect of seven anti-tuberculosis treatment regimens on sputum microbiome

*"Shorter efficacious anti-tuberculosis regimen with improved treatment outcomes might be achieved without harming the commensal microbiota."*

Recovery in respiratory microbiota looks reassuring (1st fig👇). Nice control that Mycobacterium tuberculosis no longer detected on treatment! (2nd fig👇)

#IDMastodon #infectiousdiseases #medicine #microbiome #microbiology #tuberculosis #tb #antibiotics
thelancet.com/journals/lanmic/

@jwoodgett I'm hearing from people at panels and journals who have already met them...

@cyrilpedia Wonder if we’ll see declarative “never LLMmers” like the “pure good” anti-vaccine peeps?

"Over the past week, Jews living in Germany’s capital Berlin have been waking up to a chilling sight — Stars of David sprayed on the front doors of their apartment blocks."

ft.com/content/ed744535-d04f-4

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