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“The death of human empathy is one of the earliest and most telling signs of a culture about to fall into barbarism.”

— Hannah Arendt

youtube.com/shorts/ZMj-9h8-gXU

#SilentSunday

'AI-enabled drug discovery has yet to prove itself in the clinic. And on top of that, companies have to worry about intellectual property — regarding not only the drugs but also the discovery methods. “Everybody patents molecules,” says Alex Aliper, the president of Insilico Medicine, headquartered in New York City and Hong Kong. “For algorithms, it’s a choice.”

nature.com/articles/s41587-023

A new episode of the EMBO podcast is out. I spoke with Hsiao-Han Chang, Gytis Dudas, and Hedvig Tamman about viruses, hosts, spillovers, public health... And also starting a new lab, the challenges of mobility, mentorship, and Die Hard Dracula.

embo.org/podcasts/its-viruses-

Happy to introduce our latest gizmo from the lab: pLSM !
biorxiv.org/content/10.1101/20

A big shoutout to our brilliant grad student, Yannan Chen, who led this work.

In short, pLSM is a plug-and-play, cost-effective and easy-to-scale light sheet microscopy platform. More than 20 times cheaper, with imaging quality comparable to high-end systems.

github.com/tomerlab/pLSM-Contr

#LSFM #preprint #biorxiv #lightsheet #dopamine

2004 | From HUPO Proteomics-Timeline bit.ly/3m3ZI9P - Ross et al. develop tandem mass tagging (TMT) technique

---
#proteomics #prot-other

Trains are in terrible shape, but yes let's all focus on TAP & airports

"A história tem vindo a ser relatada nas páginas do PÚBLICO: a linha ferroviária da Beira Alta, que se encontra encerrada desde Abril de 2022, permanecerá interrompida à circulação por “pelo menos mais seis meses”

publico.pt/2023/10/30/opiniao/

'Strong, durable vaccines are one of the main reasons that several countries have managed to eliminate measles—and why a paramyxovirus called rinderpest, once a major scourge of cattle, is one of the only infectious diseases we’ve ever managed to eradicate.'

theatlantic.com/science/archiv

'To eke out gains, private-equity firms have cut nursing staff, slashed services, and even, in at least one case early in the pandemic, made an explicit threat to close an institution unless it received taxpayer money. Many hospitals purchased by private-equity firms have been forced to pay consulting fees to their new overlords for access to their strategic brilliance.'

theatlantic.com/ideas/archive/

'This is a central Laurencin paradox: She thrived in an art world that was almost entirely male by painting a world filled almost exclusively by women. When Laurencin pursued the French tradition of the 18th-century fête galante painting — pastoral scenes of courtship, flirtation and romantic intrigue epitomized by the work of Antoine Watteau — she excised all the men.'

nytimes.com/2023/10/25/style/m

"Because of the attritional nature of contemporary peer review (and the level of aggression frequently encountered), successes in both papers and grants are nowadays likely to be met not with celebration, but a sense of exhausted relief. The pleasure is always fleeting."
@TIR_scienceblog

totalinternalreflectionblog.co

Interactions between #bacteriophage & mammalian hosts can facilitate diverse symbioses; @marion_bichet @JeremyJBarr &co show that mammalian cells internalize #phage, using them as a resource to enhance cellular growth & proliferation #PLOSBiology plos.io/49bc4Gu

In case it wasn’t clear what kind of person the new Speaker Mike Johnson is, here is an OpEd he wrote advising that states should “discriminate” against “homosexual conduct” and suggesting they pass laws around “sexual conduct outside marriage.” He is a Christo-Nationalist zealot. Of “The Handmaid’s Tale” variety.

It’s #BlackInMarineScience week! I’m sad to see no mention of this incredible effort here, which features an impressive lineup of events & activities. This is Year 3 of #BIMSWeek. Check out upcoming events at blackinmarinescience.org/bimsw and head to #BIMSTV to view recordings of past events youtube.com/blackinmarinescien. If you have not completely abandoned Twitter, check out twitter.com/blackinmarsci?lang for even more content. Let’s support the incredible #BIMS team!

'Strong, durable vaccines are one of the main reasons that several countries have managed to eliminate measles—and why a paramyxovirus called rinderpest, once a major scourge of cattle, is one of the only infectious diseases we’ve ever managed to eradicate.'

theatlantic.com/science/archiv

"Yet, resident and circulating Treg had distinct TCR repertoires, and each LN contained exclusive clonal subpopulations of resident Treg. Our results demonstrate that, similar to conventional T cells, Treg can form resident memory-like populations in LNs after adaptive immune responses"

science.org/doi/10.1126/sciimm

Netanyahu's orders are abhorrent, & many are war crimes, he needs to go:

"Testimonies and documents: Palestinians arrested in Jerusalem were severely beaten by police officers and prison guards."

#Netanyahu #IsraelHamasWar

haaretz.co.il/news/law/2023-10

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