Thiago Carvalho @cyrilpedia@social.cleverlibre.org

"By his mid-20s, Mr. Holmes thought about what was ahead for him — sickle cell emergency after emergency, begging for help in Alabama hospitals that saw a Black man and assumed him to be a drug addict — and he started to think about ending his life. “Every time I tried anything, the disease would come and knock me away,” he remembered. “You get tired. You get worn out.”'

https://www.nytimes.com/2023/10/30/opinion/sickle-cell-gene-therapy-crispr.html

The #chemistry of #pumpkins. #halloween

I wrote a blog entry about my return to the role of Charles Dickens, for the first time in a decade, at https://journal.neilgaiman.com/2023/10/for-two-nights-only-christmas-carol.html
NYC's TOWN HALL, Dec 18th and 19th. Tickets go on sale this Friday.

Two things are true:

There's been an explosion of really vile #antisemitism, some coming from pro-Palestinian protesters. It's terrifying.

Calls for a ceasefire and condemnation of Palestinian civilian deaths are being labeled antisemitism, even when they come from Jews. It's slanderous.

These things feed into each other.

It's a terrible time to be a pro-Palestinian, anti-occupation Jew. We're really getting hit from all sides right now.

#israel #gaza

Self-portrait as plague doctor with hand puppet.
#halloween

Hear Classic Readings of Poe’s "The Raven" by Vincent Price, James Earl Jones, Christopher Walken, Neil Gaiman & More

https://www.openculture.com/2023/10/hear-classic-readings-of-poes-the-raven.html

Where the heck did all those structures inside complex cells come from?

Scientists agree that eons ago, a bacterium took up residence inside another cell and became its powerhouse, the mitochondrion. But there are competing theories about the birth of other organelles such as the nucleus and endoplasmic reticulum.

Read more: https://knowablemagazine.org/article/living-world/2023/how-endomembrane-system-of-eukaryotic-cells-evolved?utm_source=mastodon&utm_medium=post&utm_campaign=originals

#KnowableMagazine
#ScienceMastodon
#Biology
#SciComm

In their Commentary article, Yangfan Zhang & George Lauder discuss how little we know about the energetic cost of moving as a group compared with that of solitary locomotion, given that moving in flocks, shoals and herds is ubiquitous among vertebrates

#biomechanics #locomtion #comparativephysiology #zoology #biology

https://journals.biologists.com/jeb/article/226/20/jeb245617/334300

New avenues for human blood plasma biomarker discovery via improved in-depth analysis of the low-abundant N-glycoproteome https://www.biorxiv.org/content/10.1101/2023.10.22.562384v1.full.pdf+html

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#proteomics #prot-preprint

#Netanyahu, #TFG... are perilous:

The IL PM's vengeful tweet can serve as a warning. Authoritarians never: learn, reform or take resp. If the Israelis want to recover & avoid repeated errors of strongmen *must get new leadership —before more damage can be done. Given their general willingness to submit to trad. authorities, intolerance of ambiguity & need for closure -unsurprising RW authoritarianism predicts tolerance for, & susceptibility to, misinfo. #IsraelHamasWar https://www.washingtonpost.com/opinions/2023/10/31/netanyahu-trump-strongman-israel/

The totality of all data available strongly supports masks to reduce SARS-CoV-2 spread, especially those of high quality.

New report https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2811136

New analysis of flawed Cochrane review

https://www.researchsquare.com/article/rs-3486610/v1

New article! Read mRNA vaccine encoding Gn provides protection against severe fever with thrombocytopenia syndrome virus in mice https://www.nature.com/articles/s41541-023-00771-2?utm_source=dlvr.it&utm_medium=mastodon in npj Vaccines

Postdoctoral Fellow Neuroimmunology (Louveau Lab)

Lerner Research Institute Cleveland Clinic

The Louveau lab is recruiting

See the full job description on jobRxiv: https://jobrxiv.org/job/lerner-research-institute-cleveland-clinic-27778-postdoctral-fellow/?feed_id=63862

#ScienceJobs #hiring #research
Cleveland #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/lerner-research-institute-cleveland-clinic-27778-postdoctral-fellow/?feed_id=63862

Happy to finally see this work published!
https://www.cell.com/neuron/fulltext/S0896-6273(23)00757-2

Hope this inspires more work on spike-timing changes in the context of #neurodegeneration.

#Neuroscience #Hippocampus #Placecells #ThetaSequences