The cover of this week's Lancet and the accompanying article on the UK Covid inquiry by the Editor-in-Chief
https://thelancet.com/journals/lancet/article/PIIS0140-6736(23)02504-7/fulltext
Imagine if this was done in the United States
'More than half of all British defence exports go to the Middle East – but to Saudi Arabia rather than Israel. Human rights organisations, including Amnesty International, accuse BAESystems of being party to Saudi war crimes in Yemen, where BAE-supplied (and serviced) fighters have bombed schools and hospitals.'
https://www.lrb.co.uk/the-paper/v45/n22/james-butler/up-in-arms
"Brazil is now the world’s leading consumer of highly hazardous pesticides, and the second leading consumer of all pesticides. In part, this massive consumption is because Brazil applies pesticides (per hectare) at a rate 2.3 times higher than the United States and 3 times higher than China"
@gpollara Project the poster!
It's Solomon Sunday here on Mastodon, folks! You bring your contested babies, I bring the giant sword.
"And all the while, the lice have recorded this journey in their genes. A new study, for example, found that some lice in the Americas are hybrids of those carried there by Native Americans and others ferried across the Atlantic by European colonists."
@Carl_Zimmer
#Evolution #Biology #PopGen #SciComm
Pediculus humanus, the human louse. Image Credit:Frank Collins/Centers for Disease Control and Prevention.
https://www.nytimes.com/2023/11/08/science/lice-genes-human-history.html
New article! Read Enhancing breadth and durability of humoral immune responses in non-human primates with an adjuvanted group 1 influenza hemagglutinin stem antigen https://www.nature.com/articles/s41541-023-00772-1?utm_source=dlvr.it&utm_medium=mastodon in npj Vaccines
😢😢😢 but also the water companies got away with too much for too long https://www.theguardian.com/environment/2023/nov/11/photographer-project-wildlife-lost-pollution-yorkshire-river-wharfe?CMP=Share_iOSApp_Other
"Entre los sospechosos habituales está Estados Unidos, donde más del 70% de los adultos sufren obesidad o tienen sobrepeso y donde la enfermedad es la principal causa de muerte. También México: cerca del 73% de la población excede de su peso recomendable. Además, el 34% de esas personas enfermas sufren obesidad mórbida (IMC superior a 40). En realidad, el continente americano es uno de los más azotados por este mal, que tendrá un impacto económico anual del 3,7% del PIB en 2035, de acuerdo con las estimaciones del Atlas Mundial de la Obesidad."
Group B streptococci adapt to survive in inflammation of diabetic wounds
#IDMastodon #infectiousdiseases #diabetes #microbiology #bacteria
https://www.science.org/doi/10.1126/sciadv.add3221
'Therapy-elicited neutrophils acquired an interferon gene signature, also seen in human patients, and appeared essential for successful therapy, as loss of the interferon-responsive transcription factor IRF1 in neutrophils led to failure of immunotherapy.'
Tools
"Here we present a new optogenetic CRISPR tool, BLU-VIPR, that diverges from prevailing split-Cas design strategies and instead focuses on optogenetic regulation of gRNA production."
"Ultimately, however, Factor VIII killed many of those who infused it in the 1970s and 1980s. For decades, British officials and ministers claimed that the contaminated blood scandal was a tragedy no one could have prevented: when haemophiliacs began to be infected, hepatitis C hadn’t even been named, and HIV/Aids was entirely unknown; new protocols were introduced once the dangers became clear. According to Margaret Thatcher, ‘all patients received the best treatment available in light of the medical knowledge at the time.’ These claims were not true."
https://www.lrb.co.uk/the-paper/v45/n22/florence-sutcliffe-braithwaite/we-ve-messed-up-boys
Just a few months after the launch of ChatGPT, copywriters and graphic designers (freelancers) have been affected by a significant drop in the number of contracts received, and in those that have received them - a drop in earnings. being more skilled was no shield against loss of work or earnings. Being more skilled was no shield against loss of work or earnings
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4527336 #ai #aftificialintelligence #chatgpt #gpt
“In sum, there is no denying that women’s path to leadership positions is paved with many barriers including a very thick glass ceiling. But a much bigger problem is the lack of career obstacles for incompetent men [..] The result is a pathological system that rewards men for their incompetence while punishing women for their competence, to everybody’s detriment.”
https://hbr.org/2013/08/why-do-so-many-incompetent-men
"Ultimately, however, Factor VIII killed many of those who infused it in the 1970s and 1980s. For decades, British officials and ministers claimed that the contaminated blood scandal was a tragedy no one could have prevented: when haemophiliacs began to be infected, hepatitis C hadn’t even been named, and HIV/Aids was entirely unknown; new protocols were introduced once the dangers became clear. According to Margaret Thatcher, ‘all patients received the best treatment available in light of the medical knowledge at the time.’ These claims were not true."
https://www.lrb.co.uk/the-paper/v45/n22/florence-sutcliffe-braithwaite/we-ve-messed-up-boys
"Factor VIII concentrate was developed later in the decade. Production involved pooling many batches of donated blood, then fractionating it. The Factor VIII was freeze-dried and packed into bottles. Haemophiliacs could get it out of the fridge themselves, mix it and inject it to stop bleeds. It was a miracle treatment: in 1962 the median life expectancy for severe haemophiliacs in Britain was 37; by 1980 it was practically normal."
https://www.lrb.co.uk/the-paper/v45/n22/florence-sutcliffe-braithwaite/we-ve-messed-up-boys
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com