"Our study thus reveals an unsuspected role of histone eviction from insect sperm chromatin: safeguarding the integrity of the male pronucleus during female meiosis."
In this episode we talked with Maria Gambetta from the University of Lausanne about her work on the function of insulators in 3D genome folding. #womeninstem #podcast #epigenetics
Listen here: https://activemotif.com/podcasts-maria-gambetta
"We suggest ‘phenotypic noise’ be used to distinguish non-genetic changes in phenotype that occur independently from the environment. We discuss the conceptual and methodological techniques used to identify these phenomena during cancer evolution."
https://www.sciencedirect.com/science/article/pii/S0962892423002064#f0005
'Na conversa, o jurista confirmou que o território foi sempre uma espécie de cofre para os partidos portugueses e que o dinheiro chegava em malas a Portugal. “Que eu saiba, com excepção do PCP, toda a gente lá foi”, garantiu, admitindo também que Stanley Ho, entre outros, seria uma das fontes de financiamento.'
https://www.publico.pt/2023/11/17/politica/noticia/negocios-china-lacerda-machado-2070533
Finally heard back from that rogue invited speaker? You still have time to submit your symposium proposal for #SMBE24!! Deadline is today (Nov 17)!! SMBE2024.org
"If Zoom meetings leave you feeling like something is missing, know that you’re not alone. According to a new study by researchers at Yale and University College London, staring at someone’s face on a computer screen results in lower levels of brain activity and social arousal than meeting them in person."
Not great. Gantenerumab is a monoclonal antibody against aggregated Aβ:
"Among persons with early Alzheimer’s disease, the use of gantenerumab led to a lower amyloid plaque burden than placebo at 116 weeks but was not associated with slower clinical decline."
#alzheimers
https://www.nejm.org/doi/full/10.1056/NEJMoa2304430?query=featured_home
"According to the V.A., the Million Veteran Program is the largest such database in the world. It includes not only genetic information but also is linked to the department’s electronic medical records and even contains records of diet and environmental exposure."
https://www.nytimes.com/2023/11/15/health/million-veterans-database-va.html
@LauraJMG Yes - Emily Bazelon is a great writer.
"That doctor had to be talking about Stieve, Hildebrandt says, since “there is no other ‘Nazi experiment’ like this.” It was another link in the chain from Stieve to Mecklenburg to Willke to today’s anti-abortion Republicans."
(article is fm 2013)
"Early results from an innovative new trial in how the British Academy awards its Small Research Grantssuggests that introducing partial randomisation into the selection process could lead to a more ethnically and institutionally diverse cohort of award-holders."
"The bat fossil record also provides significant evolutionary insights, although it is one of the poorest of any mammalian order, with ∼80% of the record estimated to be missing. The world’s oldest known bat fossil consists of a single, 56 mya lower molar from Portugal"
https://www.cell.com/current-biology/fulltext/S0960-9822(23)01289-7
Menu:
- Um truque inovador para reduzir o número de candidaturas a financiamento de projetos de investigação
- Um subterfúgio de secretaria para falsear as taxas de sucesso.
- A falsa regularidade dos concursos para financiamento de projetos.
"(...) in 1986, it eventually led him to #immunology—via an unusual patient. She was the wife of a government minister, a privileged woman who nevertheless had spent years being sent from one expert to another, some of whom said her problem was in her head. Her problem? She itched! Everywhere all over her skin, to the point of scratching her skin bloody. Albert was a young dermatology resident when he was asked to take care of her."
https://www.cell.com/immunity/fulltext/S1074-7613(23)00443-0?dgcid=raven_jbs_etoc_email
"To further promote good science, he worked hard at educating students and postdocs, and he became a wonderful teacher. Eschewing textbooks (because of any author’s inescapable biases), he taught from the primary literature. Students loved his classes, and he won the University of Chicago’s “Llewellyn/Quantrell award for excellence in undergraduate teaching ”, chosen from the entire University as best teacher of the year."
https://www.cell.com/immunity/fulltext/S1074-7613(23)00443-0?dgcid=raven_jbs_etoc_email
"Estas aventuras y aprendizajes infantiles se publicaron en la artesanal revista escolar de Bañuelos de Bureba (Burgos), coordinada por el maestro catalán republicano Antonio Benaiges. Tales andanzas aparecieron en el número de enero de 1936. Faltaban siete meses para que Benaiges fuese apaleado, exhibido por el pueblo y fusilado en el páramo. Lo condenaron sus modernos métodos de enseñanza y lo ajusticiaron los franquistas."
https://elpais.com/espana/2023-11-15/el-pueblo-que-nego-al-maestro-que-prometio-el-mar.html
📢 WANTED: SPONSORS! 📢
If your organisation wants to be a sponsor of an extra activity on the programme, such as academic career coaching or a transition narrative workshop, please let us know via team@openscienceretreat.eu. Sponsorship packages range from €500 to €5.000: you will be mentioned in all our outputs as sponsor and your logo will feature prominently on www.openscienceretreat.eu #OSR24NL
If you're one of those organised people who is already thinking about Christmas presents, the FT has just named Blue Machine as one of its best science books of 2023.
And one of the nicest things about the reaction to it has been that even people who have no initial interest in the ocean really love it, as well as those who start as fans. Do give the gift of the ocean this festive season!
https://www.ft.com/content/03cccd68-3eb7-4ea2-bbde-dfc567ecdf4b
From toy to tool: DALL-E 3 is a wake-up call for visual artists—and the rest of us https://arstechnica.com/?p=1972468
How our memories of COVID-19 are biased — and why it matters
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com