We have "a rare chance to unbundle the #internet, to pull apart an existing system and rebuild it, piece by piece, in vastly better ways…if the next phase of how we congregate and communicate online is built for #humans and not advertisers.
What we’ll get instead is something much bigger: an entirely new infrastructure for our online lives that no company or platform controls."
https://www.theverge.com/23990974/social-media-2023-fediverse-mastodon-threads-activitypub
Researchers have discovered a way to build three-dimensional #organoids that resemble how skeletal muscle develops in the fetus. https://elifesciences.org/digests/87081/growing-skeletal-muscle?utm_source=mastodon&utm_medium=social&utm_campaign=organic
'E para os britânicos casados ou em união de facto com um imigrante nada está garantido, estando o cônjuge em risco de não poder ficar caso o outro elemento do casal não ganhe pelo menos 38.700 libras e centenas de milhares de famílias desfeitas numa terra onde apenas os mais abastados têm direito a uma vida conjugal.'
https://www.publico.pt/2023/12/25/p3/cronica/vida-reino-unido-impossivel-2074633
"Venice was a city of printers and readers. In his World of Aldus Manutius, Martin Lowry made a rough guess that, in 1500, Venetian presses produced twenty books per member of the city’s population. There were more printshops – and more booksellers, stationers, bookbinders – in Venice than anywhere else in Europe: twice as many editions were printed there than in Paris, its closest rival."
https://www.lrb.co.uk/the-paper/v45/n24/erin-maglaque/case-endings-and-calamity
The gift that keeps on giving:
"Os governos que saíram vencedores da II Guerra Mundial não deram de imediato atenção à ideia de criar uma carta de direitos para a Humanidade, interessados que estavam em discutir esferas de influência e em arquitetar a Carta das Nações Unidas de maneira a garantir os seus poderes de veto"
#IDMastodon #Covid especially in vaccinated people the most common symptom is “sneezing”. So if you are sneezing on top of other ,known your symptoms & please get a RATest done- Don’t spoil 🎄 for everyone ,the advice to health professionals to return to work even if +ve RATest is simply reckless…
'Candice Breitz, Deborah Feldman and Masha Gessen are just the latest to be ‘lectured’, as Eyal Weizman put it, ‘by the children and grandchildren of the perpetrators who murdered our families and who now dare to tell us that we are antisemitic’.'
https://www.lrb.co.uk/the-paper/v46/n01/pankaj-mishra/memory-failure
"The Chinchorro culture began mummifying their dead in what is now southern Peru and northern Chile around 6000 bce, making South America’s earliest mummified bodies two thousand years older than those of Egypt."
https://www.lrb.co.uk/the-paper/v46/n01/erin-l.-thompson/even-the-eyelashes
'Measles cases continued to pop up here and there in the densely populated city in 1989 and 1990 — as is common with highly contagious infectious diseases. But measles never managed to get a firm grip on any particular neighborhood or community in that two-year period, in part because the vaccination rate among the overall population was reasonably good. That all changed once the illness made its way to the Faith Tabernacle school.'
https://www.phillymag.com/news/2021/03/20/philadelphia-measles-outbreak-1991/
Fake news BC
"En plein Sénat, Caton laisse échapper quelques figues gorgées de jus, comme tombées par mégarde des plis de sa toge. Lorsque ses collègues s'extasient, Caton jure qu'il les ramène de Carthage –et que si elles sont si appétissantes, c'est parce que l'ennemie jurée n'est qu'à trois jours de Rome. Caton a menti: la traversée prend au mieux six jours et il y a toutes les chances que les fameuses figues soient venues de ses propres plantations. Mais qu'importe: le souvenir d'Hannibal est ravivé. Dans le doute, il faut raser Carthage."
https://www.slate.fr/culture/histoires-sans-fin/carthage-incendie-scipion-emilien-rome-resistance
'Taken together, we report on mRNA vaccines targeting P. vivax and demonstrate that Pvs25 mRNA–LNP outperformed an adjuvanted Pvs25 protein vaccine suggesting that it is a promising candidate for further testing in non-human primates.'
"First, they looked in the genes for clues, and genetic scans showed that inflammation genes were dialled down throughout multiple organs. This was a good lead as inflammation is a risk factor for age-related diseases such as cancer, arthritis and heart disease. To double-check, they took blood samples to look for signs of inflammation; there were fewer pro-inflammatory molecules in the blood of mice with heavy hyaluronan. Finally, they did a third test, by injecting a bacterial protein that causes inflammation and checking how the mice reacted. There was less inflammation in their tissues, and fewer pro-inflammatory chemicals in their blood. This may be naked mole rats’ secret of youth: this thick hyaluronan coating may protect cells from inflammation, so they live longer and avoid disease."
Recent moves of note in and around the biotech and pharma industries https://go.nature.com/3v8fYR5
https://rdcu.be/dudqw
Colograph by @madparreira.bsky.social
The works presented here are created with alternative materials rather than etched on copper #art #print #printmaking #colograph #artgallery #hadmade #artmastodon
Well, I don't like them. They wet their nests.
"Huxley wrote extensively for popular audiences, frequently appeared on radio and television and even directed an Oscar-winning wildlife film, The Private Life of the Gannets."
"However, the metrics generally used to evaluate protein structure prediction methods—including all of those used in CASP—focus on the overall accuracy of predicted structures, rather than on their utility in predicting ligand binding. This has left the large community of academic and industrial researchers who wish to use protein structures to design drugs and other ligands unsure of whether, when, and how to use the new structural models. Improvements in protein structure prediction are widely assumed to lead to better models of ligand-binding pockets and thus more accurate predictions of ligand binding (Beuming and Sherman, 2012; Bordogna et al., 2011; Erickson et al., 2004), but to what extent do these assumptions hold?"
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com