'Whereas most new cancer drugs afford modest benefits,2approved drugs or those in development may be heralded as “game changers” or “breakthroughs” in the lay press. These news articles may be important sources of information to patients, the public, and investors—with a broader reach than medical journal articles. However, omission of medical context or use of inflated descriptors may lead to misunderstandings among readers.'
https://docteur.nicoledelepine.fr/the-use-of-superlatives-in-cancer-research/
"However, when similar flight paths are compared across conditions, the stability of the hippocampal code persists."
Doesn't this mean that "place cell" is a misnomer (for such firing patterns)? They're really "place+trajectory" cells. Shouldn't a "true" place cell be path-invariant?
Credit-assigning on such invariant reps is presumably needed somewhere in the system in order to drive flexible navigation, no?
"In many cases, Dr. David found, images in the papers had been stretched, obscured or spliced together in a way that suggested deliberate attempts to mislead readers. The studies he flagged included some published by Dana-Farber’s chief executive, Dr. Laurie Glimcher, and its chief operating officer, Dr. William Hahn."
#ResearchIntegrity
https://www.nytimes.com/2024/01/22/health/dana-farber-cancer-studies-retractions.html
'The new call for HFSP Research Grants has just opened with a deadline in March. You need to get into the application system and initiate an application by 19 March 2024, at the latest, and submit the complete Letter of Intent by 28 March 2024.'
https://network.febs.org/posts/wanted-super-creative-researchers-urged-to-apply
From HHMI on LinkedIn
"The #HannaGrayFellows team will be holding an informational webinar on January 22nd and February 2nd, both from 3:30-4:30pm ET, to answer your questions about the program and the application."
"The first malaria vaccination campaign for children backed by the World Health Organization begins in Africa on Monday, with the distribution of nearly 30mn jabs in the coming months marking a milestone in the fight against the tropical disease."
#Malaria #Vaccine #immunology
https://www.ft.com/content/b6f03756-86ab-4912-aad0-9384198673ad
Neuronal traffic control: How microtubule motors coordinate transport along the length of the axon.
New study by @afellows et al. uses live imaging to provide new insights. #Preprint evaluated on @prereview.
'The new call for HFSP Research Grants has just opened with a deadline in March. You need to get into the application system and initiate an application by 19 March 2024, at the latest, and submit the complete Letter of Intent by 28 March 2024.'
https://network.febs.org/posts/wanted-super-creative-researchers-urged-to-apply
Tools.
"To improve the effectiveness of prime editing in hPSCs, we systematically compared and combined the "inhibition of mismatch repair pathway and p53" on top of the "PEmax" to generate an all-in-one "PE-Plus" prime editor. We show that PE-Plus conducts the most efficient editing among the current PE tools in hPSCs."
#Preprint
I am looking for a good course/school for #alphafold usage. Better in Europe, but I am up for traveling more. Any suggestion? #bioinformatics
Small predators that could save our lives
by Jéssica Gil Serna
https://schaechter.asmblog.org/schaechter/2024/01/small-predators-that-could-save-our-lives.html
#microbiology
Elizabeth Holmes barred from federal health programs for 90 years
Fucked about, found out.
Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids https://www.biorxiv.org/content/10.1101/2024.01.21.576532v1?med=mas
Topographic, cognitive, and neurobiological profiling of the interdependent structural and functional connectome in the human brain https://www.biorxiv.org/content/10.1101/2024.01.21.576523v1?med=mas
California State University faculty may begin a week-long walkout tomorrow. Information and resources for CSU and Cal Poly students: https://www.calfac.org/resources/student-faq/
'As the Norwegian historian Camilla Mørk Røstvik notes in Cash Flow, the “menstrual economy” is booming, expected to reach $27.7 billion by 2025.
Cash Flow describes the rise of this industry through a series of case studies from 1945 to the present, showing how the development and marketing of various menstrual products has at times catalyzed, at other times mirrored, seismic economic and cultural shifts around the world.'
https://www.nybooks.com/articles/2024/02/08/month-to-month-period-the-real-story-of-menstruation/
I have the wonderful privilege of giving interactive art museum tours to young kids. The other day I asked a quiet 2nd grader who was enthralled by a Dorothea Lange photo from the Great Depression what he thought was going on in the photo. His interpretation was thoughtful and perceptive. After praising his response he came back with “my grandma taught me to look for the secrets in art.” Yay for grandmothers!
#Art #Kids #Grandmothers #Museums #Photography
@flavia_feijo_epi Thank you!
Alternative link without paywall:
Cameroon starts world's first malaria vaccine program for children
January 22, 2024
The Associated Press
https://ca.news.yahoo.com/cameroon-starts-worlds-first-malaria-050442719.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com