Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
'Herein, we describe a synapse formation between α-SMA+ CAFs and regulatory T cells (Tregs) in the TME. Foxp3+ Tregs were localized close to α-SMA+CAFs in diverse types of tumor models as well as biopsies from melanoma and colorectal cancer patients.'
Thiago Carvalho
boosted
'Here, we demonstrated that the presence of ECM supported the growth of invasive breast cancer cells, but not non-transformed mammary epithelial cells, under amino acid starvation, through a mechanism that required macropinocytosis-dependent ECM uptake'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002406
Thiago Carvalho
boosted
Stuck on a technical neuroscience issue? We have an open, online community for that! Ask questions & post answers on Neurostars - our Q&A forum with >10K users!
'The importance of women and black artists and thinkers to Surrealism’s evolution is only beginning to be recognised. It yields new ground, partly explaining Surrealism’s recent surge as museums worldwide seek to balance their collections by gender, race, place. Surrealism’s global reach is rewarding: whereas Impressionism and Cubism, also Paris-based, became merely imitative when artists further afield adopted them, Surrealism took fire as it travelled and mutated.'
https://www.ft.com/content/545add93-4808-4952-bfc4-cf9fa36b62ad
Thiago Carvalho
boosted
More Fugitive Uterus Acts - Lawyers, Guns & Money
https://www.lawyersgunsmoneyblog.com/2024/01/more-fugitive-uterus-acts
A model for predicting vaccine-related adverse events.
"A novel reactogenicity scoring framework accounting for the frequency and severity of local and systemic AEs was applied to the clinical data, and a machine learning approach was employed to predict the incidence of clinical AEs from the in vitro assay data. Biomarker analysis suggested that the relative levels of IL-1B, IL-6, IL-10, and CCL4 have higher predictive importance for AE risk."
Thiago Carvalho
boosted
'We didn’t get a name for algorithms until a couple thousand years later, when European scholars translated Kitab al-Jabr wa-l-Muqabala (“The Compendious Book on Calculation by Completion and Balancing”), the landmark work of Persian mathematician al-Khwarizmi, from Arabic to Latin. Those researchers also Latinized al-Khwarizmi’s name to “Algoritmi,” which was then used to describe mathematical processes. We also get the word “algebra” from the book’s shortened title (Al-Jabr).'
https://lareviewofbooks.org/article/drowning-in-mediocre-data-on-kyle-chaykas-filterworld/
Thiago Carvalho
boosted
'By the close of the Indian Wars in the late 19th century, fewer than 238,000 Indigenous people remained, a sharp decline from the estimated 5 million to 15 million living in North America when Columbus arrived in 1492.'
(via @PapyrusBrigade)
https://www.history.com/news/native-americans-genocide-united-states
Thiago Carvalho
boosted
'Não podemos querer uma economia avançada e não oferecer uma democracia avançada. Onde é que está a participação cidadã no PRR? Quantos problemas poderíamos ter poupado se tivéssemos envolvido mais a sociedade civil em escolhas que podem ir desde um Data Center, em Sines, à localização do novo aeroporto?'
"The only known species of caenagnathid from this time and region was Anzu, sometimes called the “chicken from hell.” Covered in feathers and sporting wings and a toothless beak, Anzu was roughly 450 to 750 pounds (200 to 340 kilograms). Despite its fearsome nickname, though, its diet is a matter of debate. It was likely an omnivore, eating both plant material and small animals."
Image: Zubin Erik Dutta / PLOS One.
#Scicomm #dinosaur #paleontology #fossils
Thiago Carvalho
boosted
🚨 We demand the immediate liberation of #ColineFay, a 26yo environmental & human rights activist facing life imprisonment in Senegal!
‼️ Peacefully demonstrating is not a crime @mincolonna
@emmanuelmacron
#FreeColine #HomeForChristmas
Thiago Carvalho
boosted
“74% of company-internal data protection professionals say that authorities would find significant violations at an average company”.
@noybeu marks Data Protection Day with new research that reveals Europe’s failure to apply the GDPR. https://noyb.eu/en/data-protection-day-74-experts-see-relevant-violations-most-companies
Ceramic chess set by @madparreira.bsky.social
#art #ceramics #stoneware #handmade #artgallery #pottery #chess #arts #artmastodon
Thiago Carvalho
boosted
Safe country -really? In the last few months refugees been granted asylum in uk for credible risks of harm https://www.theguardian.com/world/2024/jan/27/well-camouflaged-dictatorship-rwandans-fear-for-safety-while-dirty-tricks-campaign-undermines-critics?CMP=Share_iOSApp_Other
Thiago Carvalho
boosted
Title: Crow on a Snowy Branch (c.1910)
Artist: Ohara Koson
https://www.nippon.com/en/japan-topics/g01004/ #ShinHanga #OharaKoson #Taisho #Winter #Snow #Crow #Karasu #Japan
'Os números argumentam por mim. Em 2023 o índice Housing Anywhere categorizou Lisboa como a cidade mais cara da Europa onde um T1 custa em média 2500 por mês. Também o ano passado, a Confidencial Imobiliário classificou o preço médio dos apartamentos em oferta em Lisboa em 677,8 mil euros, valor em linha com o total de um ordenado médio português ao longo de 40 anos.
Estas casas não são para nós, não existem para vivermos nelas.'
https://www.dn.pt/4577283438/a-cidade-financeira-e-o-deserto-das-nossas-vidas/
Thiago Carvalho
boosted
russia behind massive #disinformation campaign to undermine support for #Ukraine in #Germany
Analysts from the German Foreign Ministry examined a massive amount of data on #Twitter (X) between 20 December and 20 January. During this period, they found over 50,000 fake user accounts ....... involved in coordinated German-language information campaigns
Read more here 📎
https://euromaidanpress.com/2024/01/27/spiegel-russia-behind-massive-disinformation-campaign-to-undermine-support-for-ukraine-in-germany/
Thiago Carvalho
boosted
English author, poet, mathematician and photographer Charles Dodgson was born #OTD in 1832. Within the academic discipline of mathematics, Dodgson worked primarily in the fields of geometry, linear and matrix algebra, mathematical logic, and recreational mathematics, producing nearly a dozen books under his real name. To promote letter writing, Dodgson invented "The Wonderland Postage-Stamp Case" in 1889.
Books by Lewis Carroll at PG:
https://www.gutenberg.org/ebooks/author/7
We're #1
"Democrats fear Joe Biden is sleepwalking to disaster in a November rematch with Donald Trump. Tories level similar criticism at dozy Rishi Sunak as Labour dreams of an autumn landslide. But for a truly world-beating slumber party, EU leaders take the bedtime biscuit."
'Here, we show that Arachidonic Acid inhibits the NLRP3 inflammasome, through a PLC-JNK-dependent mechanism, to supress IL-1β production under physiological conditions. This provides a mechanistic basis for how dietary manipulation such as fasting influences the inflammatory state and is likely to be critical for reducing the metaflammation underpinning many diseases induced by the Western Diet.'
#Immunology #Inflammation #inflammasome #Metabolism
https://www.cell.com/cell-reports/fulltext/S2211-1247(24)00028-7
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
