Thiago Carvalho @cyrilpedia@social.cleverlibre.org

'Molecules in a cell constantly interact with each other in a self-organizing manner, creating a dynamic subcellular organization with higher-order macromolecular assemblies in astonishing complexity in a tightly regulated choreography. This molecular sociology of cells is not well understood. Hence, we need a new conceptual framework, language, and technical tools to bridge the gap from single molecules to the entirety of the cell.'

https://www.cell.com/cell/fulltext/S0092-8674(23)01349-1

"The current call targets advanced female PhD fellows, postdoctoral scholars, and tenure-track group leaders holding a primary affiliation with a research group/programme based in Africa."
#InfectiousDisease #InfectionImmunity #ResearchFunding #Immunology

https://www.embl.org/about/info/scientific-visitor-programme/fellowships/embl-unesco-fellowships/

New #FlyBook chapter!
Bone morphogenetic protein signaling: the pathway and its regulation https://academic.oup.com/genetics/article/226/2/iyad200/7485567

Polygenic risk scores — a patient’s chance, based on tiny DNA variants, of developing cardiovascular disease, breast cancer and more — are coming to clinics. But there are kinks to iron out and accuracy remains an issue. https://knowablemagazine.org/content/article/health-disease/2024/polygenic-risk-score-genes-heart-disease-cancer-coming-to-clinic via @KnowableMag

#KnowableMagazine #ScienceMastodon

News in Proteomics Research blog post | Reflections on the EuBiC Winter School (Guest blogger post!) https://proteomicsnews.blogspot.com/2024/02/reflections-on-eubic-winter-school.html

---
#proteomics #prot-other

"there is nothing radical about a wealth tax, a national care service or an ambitious insulation programme: this is mainstream social democracy. By deleting these policies, he is not bowing to “centrism”, but to an extreme agenda of austerity, privatisation, poverty and environmental destruction"

If disillusionment is all Keir Starmer delivers as prime minister, I fear Labour will shrivel and die | George Monbiot | The Guardian
https://www.theguardian.com/commentisfree/2024/feb/11/keir-starmer-labour-party-british-democracy

"Just a few years ago creating a deepfake would have required advanced technical skills, but generative AI has made it stupidly easy and accessible, and the outputs are looking increasingly realistic. Even reputable sources might be fooled by AI-generated content. For example, users-submitted AI-generated images purporting to depict the Israel-Gaza crisis have flooded stock image marketplaces like Adobe’s."

https://www.technologyreview.com/2024/01/04/1086046/whats-next-for-ai-in-2024/

"Due in part to changes driven by the infamous Common Core standards, teachers now have to fight to assign their students longer readings, much less entire books, because those activities won’t feed directly into students getting higher test scores, which leads to schools getting more funding."

https://slate.com/human-interest/2024/02/literacy-crisis-reading-comprehension-college.html

C++ Research Software Engineer with DevOps Expertise @samweingamgee

University of Tuebingen

Come live in a German medieval university town! We seek a software engineer to help build our #FOSS project #OpenMS. 6 weeks vacation, full benefits.

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-tuebingen-27778-c-research-software-e...
https://jobrxiv.org/job/university-of-tuebingen-27778-c-research-software-engineer-with-devops-expertise/?feed_id=71385

My new post on where we are with Covid (wave going down), the NHS (bad but lucky not to be worse) and the Covid vaccination programme - and a plea for a change in how we think about vaccination.

https://open.substack.com/pub/christinapagel/p/where-are-we-with-covid-in-england?r=8zv6v&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

Apoptotic #mitochondrial outer membrane permeabilization MOMP is #proinflammatory because of mitochondrial membrane protein ubiquitylation leading to NEMO recruitment and NF-kB activation

Stephen Tait and colleagues

https://www.embopress.org/doi/full/10.1038/s44318-024-00044-1

In this 'New PI diaries' post, Margot Smit reflects on the past four months as a junior group leader #NewPI @ZMBP_Tuebingen
🌱 - give it a read! 👇
https://thenode.biologists.com/setting-meeting-and-adjusting-my-expectations/careers/