Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
@ilsk @ct_bergstrom I think SF is going with an alternate rule trio
Strike first.
Strike hard.
No mercy
Thiago Carvalho
boosted
Your reminder that Barbara McClintock was awesome for more reasons that just discovering mobile genetic elements:
"Barbara McClintock was at that time correlating phenotypic changes in maize plants with cytogenetic alterations in the chromosomes. In crosses involving ring and normal linear chromosomes, chromosome breakage would occur and she could follow the fate of the broken ends. These studies led McClintock to propose that a natural chromosome must differ from broken chromosomes in possessing a structure that provides stability to the end"
From Carol Greider's 1996 @AnnualReviews article.
https://www.annualreviews.org/doi/10.1146/annurev.bi.65.070196.002005
Thiago Carvalho
boosted
Today those police-defunding leftists on the City of San Francisco board of supervisors voted to let cops use robots to kill people by blowing them up.
https://www.sfgate.com/politics/article/San-Francisco-approves-lethal-robots-17619556.php
Thiago Carvalho
boosted
Our collaborators at the University of Copenhagen are looking to hire 2 postdocs in #sustainable #MachineLearning.
Start date: 1 April 2023 or as soon as possible thereafter
https://candidate.hr-manager.net/ApplicationInit.aspx/?cid=1307&departmentId=18970&ProjectId=158002
Thiago Carvalho
boosted
Fantastic to learn that the Leverhulme Trust is going to fund masters and PhD studentships for under-represented students to increase access to research careers. Bravo! 👏
We're losing too many excellent undergraduate students from research in the UK because they can't afford to complete masters courses now often required for admission to PhD studies.
(With a 2.i and no access to funds for a masters I would be unlikely to get on a PhD scheme now!)
Thiago Carvalho
boosted
RT @WuLabHarvard
So excited that we finally have the ACTIVE NLRP3 inflammasome structure, thanks to super talented Le Xiao @LeXiao17, and Venkat Magupalli @MagupalliVenny! https://www.nature.com/articles/s41586-022-05570-8
Thiago Carvalho
boosted
@cyrilpedia This is cool and reminds me of the work by the Singer lab, showing that Lck association with co-receptors drives MHC restriction. I still find it surprising that thymocytes with 'free' Lck can yield MHC-independent, thymocyte development.
@Rahimilab Yes - and also the great paper earlier this year from the Singer lab swapping the Cd4 and Cd8 coding sequences in their "flip flop" mice
Thiago Carvalho
boosted
I'm a professor at a public university, cell biologist and geneticist who studies chromosome segregation in C. elegans during both development (mitosis) and sexual reproduction (meiosis).
I am also a passionate and committed advocate for equity in academic science
I enjoy my work, in all its forms, food (eating and cooking) and cocktails (in all its forms, but particularly the brown varieties 🥃 ).
What up, y'all?
Thiago Carvalho
boosted
New #preprint from our lab 🎉 
We report an iLID-nanobody fusion to enable #optogenetic recruitment to #GFP. This is potentially interesting when you already have a cell line or model organism expressing a GFP fusion protein.
https://www.biorxiv.org/content/10.1101/2022.11.24.517828v2
Thiago Carvalho
boosted
Hi All! Happy to be here - this is my #introduction. I'm an assistant professor at the University of Amsterdam and we are creating and applying fluorescent probes for imaging of cells with microscopes.
I'm also interested in image analysis and #dataViz with #opensource tools.
Thiago Carvalho
boosted
Seven #European institutions have joined forces to create a #database of 34,000 new images of #medieval items, including #manuscripts, #books, and $coins. With a collection of over 600 medieval manuscripts, the #digitized objects are now #online and available for the general public in the Europeana Web Portal
#History
https://aleteia.org/2022/11/25/30000-medieval-items-are-available-online-for-the-first-time/
Thiago Carvalho
boosted
Via @BioacousticsAU:
Two interesting #postdoc positions in #bioacoustics available in Norway #NTNU for anyone looking!
Thiago Carvalho
boosted
RT @medrxivpreprint@twitter.com
#PeerReview from @eLife@twitter.com of 👉🏿 The impact of the Covid-19 pandemic on Italian population-based cancer screening activities and test coverage: results from national cross-sectional repeated surveys https://www.medrxiv.org/content/10.1101/2022.08.15.22278787v1?pr=yes&versioned=true #medRxiv #reviewedpreprint
🐦🔗: https://twitter.com/medrxivpreprint/status/1597917146385944576
"The existence of successful class mismatched T cells in the periphery—those that demonstrate high specificity and are signaling competent—could thus reflect a specific subset of cells that have escaped thymic development mechanisms, or they could be rare instances of pedestrian, class-restricted T cells that express a TCR nonetheless cross-reactive with a mismatched MHC ligand."
Thiago Carvalho
boosted
RT @MolSystBiol@twitter.com
Interested in working as a scientific editor? There are two open positions @EMBOPress@twitter.com (one for @MolSystBiol@twitter.com - @EmboMolMed@twitter.com & one for @embojournal@twitter.com
Apply by Dec 11, more info below ⬇️ https://twitter.com/EMBOPress/status/1592516837723734017
🐦🔗: https://twitter.com/MolSystBiol/status/1597508904228769792
Thiago Carvalho
boosted
If you're organising a #meeting and would like support to reduce the #environmental impact of your event, our #Sustainable Conferencing #Grants might be able to help.
You can find out more about how the Indian C. elegans meeting used their grant in this story. The organisers brought the #nematode community together and ensured that the meeting had an environmental focus:
https://sustainability.biologists.com/blog/the-indian-c-elegans-meeting-goes-green/
Details about our meeting grants can be found here:
Thiago Carvalho
boosted
Tomorrow! A #Drosophilid #Science #Advent of #UK #Flies with #MacroPhotography, #NaturalHistory and #Entomology facts. Pre-advent:
‘The’ fly, D. melanogaster: winner of 6 #NobelPrizes, Dmel is a global human commensal that evolved in South East #Africa in association with #Marula https://www.sciencedirect.com/science/article/pii/S0960982218313629. Leaving Africa >20Kya https://academic.oup.com/gbe/article/11/3/844/5304659, it reached TH Morgan’s lab in 1908; ~1000 genomes are available https://popfly.uab.cat/ and wild Dmel can look pretty odd: https://bmcecolevol.biomedcentral.com/articles/10.1186/s12862-014-0179-y
Humpback hits
'Songs evolve over time, and differ across populations. This slow evolution can be occasionally interrupted by a kind of revolution, in which one population completely adopts the songs of another in a period of just a couple of years or less. “It’s like a new hit song,” Niksic said—a wide and rapid spread of creative content that’s “unparalleled in the animal kingdom, excepting humans.” She went on, “There’s so many similarities between their culture and ours.”
https://www.newyorker.com/science/elements/how-a-marine-biologist-remixed-whalesong
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
