@tackley The one that freaked me out 30 years ago in Invertebrates 101 are the rhizocephalan crab parasites in the Sacculina genus. Look them up when you're searching for horror themes.
🌟To early career women PIs with one NIH grant:
Check out this supplement! Can provide up to $70K to offset 'critical life events' including birth, adoption, or other caregiving. Maybe could help offset some of the burdens people have faced during COVID
https://grants.nih.gov/grants/guide/notice-files/NOT-OD-23-032.html
@tackley Yes - and there is a subgenre of cat memes dedicated to toxo as the agent of feline domination of humans.
Can gastrointestinal hormones modulate our reward responses? @cecivez and I ventured into the available data and literature to find that
🎯 ghrelin enhances reward responses within the motivational circuit! w/ @nbkroemer
Find more in our pre-print: https://www.biorxiv.org/content/10.1101/2022.11.30.518539v1
#gutbrainaxis #reward #fMRI #ghrelin #GLP1
So happy to see that you can use a .gif for your header here. Having a little fun with that to show y'all the full look at one of my favorite microscope images of a #macrophage (#immune cell) in the process of slurping up the bacteria that causes #Lyme disease. Showing that here alongside my favorite single slice.
#Drosophila #Advent Day2: The other UK member of the melanogaster group is D. suzukii, or “Spotted Wing Drosophila” #SWD. A fearsome #soft-fruit #pest with a saw-like ovipositor https://academic.oup.com/jee/article/114/5/1950/6369578, Dsuz originated in the far east and has recently spread around the world https://academic.oup.com/mbe/article/37/8/2369/5821433, being first recorded in the UK in 2012 https://www.researchgate.net/publication/280066071_First_record_of_Drosophila_suzukii_Matsumura_Diptera_Drosophilidae_in_Great_Britain. Dsuz is very cold tolerant compared to its relatives, with a larger, darker, tougher over-wintering adult form https://onlinelibrary.wiley.com/doi/full/10.1002/ece3.6517
"Here we analyze data from 828 children in Kilifi, Kenya with severe, uncomplicated, and asymptomatic malaria infection over 18 years of falling malaria transmission. We examine markers of host immunity and metabolism, and markers of parasite growth and transmission investment. We find that inflammatory responses and reduced plasma lysophosphatidylcholine levels are associated with markers of increased investment in parasite sexual reproduction (i.e., transmission investment) and reduced growth (i.e., asexual replication)."
#Malaria #Plasmodium #preprint
https://www.biorxiv.org/content/10.1101/2022.11.29.518379v1?med=mas
Wrapping up an Intro course with one of my favorite topics: Consciousness (C)!
I really like how @anilkseth parses the conceptual space of C in this essay (a precursor to his recent book, Being You):
https://aeon.co/essays/the-hard-problem-of-consciousness-is-a-distraction-from-the-real-one
There's:
C level (awake vs coma);
C content (awareness);
C self (that little person in our heads who is driving it all; free will).
On the topic of free will & the brain, do you know of references appropriate for early undergrads? (No Penrose please).
RT @NatRevDrugDisc@twitter.com
For readers interested in the history of immune checkpoint inhibitors for cancer therapy, here's a recent perspective https://go.nature.com/3FhRN53
🐦🔗: https://twitter.com/NatRevDrugDisc/status/1598340114668732417
New job opening for a Research Fellow in Outbreak Analytics at MRC Gambia, joining the wider Epiverse initiative. Deadline 12 Dec: https://jobs.lshtm.ac.uk/vacancy.aspx?ref=MRC-MRC-2022-09
A Gull photobombs a panoramic view of Marseille. Marseille, a port city in southern France, has been a crossroads of immigration and trade since its founding by the Greeks circa 600 B.C. At its heart is the Vieux-Port (Old Port), where fishmongers sell their catch along the boat-lined quay.
https://pixels.com/featured/marseille-scenes-8-john-hughes.html
#BuyIntoArt #Marseille #France #gull #bird #birds #BirdsOfTwitter
Our new review of engineering NK cells for cancer immunotherapy
@BiologyOpen@twitter.com
@Co_Biologists@twitter.com
#immunotherapy #NKcells #CARNK
https://journals.biologists.com/bio/article/11/12/bio059396/284640/The-prospect-of-genetically-engineering-natural
Lovely post by Darren Dahly on not being a 'real' statistician, but the importance of 'applied' statisticians, and why we need more of them: https://statsepi.substack.com/p/im-not-a-real-statistician-and-you. As a 20% statistician myself, I could not agree more!
Mondrian Crescent
I love it when train doors align at the end of a tunnel. The red tiles at Green Park station make this the ideal location to capture this moment.
It wasn't luck though, instead I froze the moving train with a fast shutter. It took ages to get it centred.
This final image resembles an abstract art painting by Piet Mondrian.
#art #mastoart #abstract #architecture #photography #potd #symmetry #london #underground #londonunderground #railway #mondrian #tiles #photo
#Neurolgy #neuroscience Lecanemab slows speed of cognitive decline, but possible links to serious brain hemorrhages concern and new antibody treatment for Alzheimer’s, safety and benefit questions persist @aaas
https://www.science.org/content/article/hail-new-antibody-treatment-alzheimers-safety-benefit-questions-persist
"When Zhengzhou started registering Covid-19 infections in mid-October, Foxconn put its plant under “closed loop” management, barring staff from leaving the site. But as infections started spreading inside the factory town, many workers fled the campus."
https://www.ft.com/content/083e038c-9b10-45d1-85e2-3eb339313a38
2 open PhD positions and 1 technican position in Barcelona, at the Brain, Circuits and Behavior lab.
https://braincircuitsbehavior.org/
Deadline: December 20th, 2022.
Apply: https://braincircuitsbehavior.org/news-posts/open-position-animal-technician-ndfrp
PhD project 1:
"Circuit mechanisms of priors and learning during decision making"
PhD project 2:
"The neural basis of working memory history biases as components of statistical learning"
Technician:
https://braincircuitsbehavior.org/news-posts/open-position-animal-research-lab-technician
#neuroscience #neurobiologia #PhD #academia #science #ciència
The worst: Mole ponders how to deal with rejection and provides guidance on how to review a paper - "Be nice, please!"
https://journals.biologists.com/jcs/article/135/22/jcs260666/282115/The-worst
#cellbiology #research #J_Cell_Sci #peerreview
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com