Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
'Although the molecular cause of sickle cell had been known since 1956, pharma had never shown much interest. Industry had yet to realize that rare diseases could be lucrative. And the few they invested in tended to be conditions, like hemophilia and cystic fibrosis, that primarily affected white people. CF also received far more philanthropic and government funding, greasing the wheels for therapies that have transformed the disease.'
Thiago Carvalho
boosted
A little BBC Radio 4 news: You can hear the audio adaptation of my story The Sleeper and the Spindle in the UK on the radio on the 24th and the 26th, https://www.bbc.co.uk/programmes/m000qm49, and hear me with the BBC Symphony on Friday & Friday Week: https://www.bbc.co.uk/programmes/m000cl2r and https://www.bbc.co.uk/programmes/m000cp2b. And after broadcast they will be available anywhere in the world using the websites or the BBC Sounds App.
Thiago Carvalho
boosted
NEW on our website
🇧🇷 As Bolsonaro emulates Trump, Brazilian journalists struggle to cover his supporters.
In a piece featuring editor Camila Mattoso, researcher Jorge Chaloub and reporter Yan Boechat, our contributor Murillo Camarotto analyses how to report on a movement whose goal is to replicate #January6th in Brazil https://reutersinstitute.politics.ox.ac.uk/news/bolsonaro-emulates-trump-brazilian-journalists-struggle-cover-his-supporters
'Using Drosophila melanogaster wing shape, we ask if we can replicate allelic effects of polymorphisms first identified in a GWAS (Pitchers et al. 2019) in three genes: dachsous (ds ), extra-macrochaete (emc) and neuralized (neur), using artificial selection in the lab and bulk segregant mapping in natural populations.'
#Preprint #Evolution #GeneticVariation #Adaptation #Preprint #Drosophila
https://www.biorxiv.org/content/10.1101/2022.05.12.491649v2
Thiago Carvalho
boosted
🚨#JOB OPENING 🚨
Hey #science people! We are recruiting for a new faculty position at the Center for #Virology and #Vaccine Research at #Harvard and Beth Israel Deaconess Medical Center. It’s for an Assistant or Associate Professor position.
Diverse perspectives are a must so PLEASE FORWARD to your women and underrepresented (#URM) colleagues in particular.
https://jobs.sciencecareers.org/job/619754/assistantassociate-professor
Thiago Carvalho
boosted
RT @MostlyPhysics
Big news – the @ERC_Research Scientific Council has decided to sign the Agreemeent on Reforming Research Assessment #ReformingRA (see last paragraph)! An excellent further evidence of the great momentum that #CoARA is keeping up.
Thiago Carvalho
boosted
Our group is moving to the University of Bonn@ UniBonn and @DZNE_en. We are sad to say goodbye to our home for last 5 years @ISD_Research. I am filled with gratitude for the fun collaborations and the alps. To those around Bonn region, I’d love to connect!
Thiago Carvalho
boosted
My argument, at its core, is that to do that, we need to teach people why science deserves their trust – and this requires teaching how science works as a social institution. I've written about this in brief in a Science American article: https://www.scientificamerican.com/article/to-fight-misinformation-we-need-to-teach-that-science-is-dynamic/
Thiago Carvalho
boosted
I just used https://fedifinder.glitch.me to import people I follow on Twitter as followers here. It worked well.
Thiago Carvalho
boosted
What if we could trace #cytotoxic #Tcells throughout the human body before and during #cancer #immunotherapy?
Researchers at the University of Groningen have used a CD8-specific positron emission tomography (#PET) tracer in a phase 1/2 clinical trial. Patients with solid tumors were imaged before and ~30 days after starting treatment with #antibodies against PD-L1, PD-1, and/or CTLA-4.
Article in Nature Medicine: https://www.nature.com/articles/s41591-022-02084-8
Thiago Carvalho
boosted
REGISTRATION IS NOW OPEN The ageing genome: from mechanisms to disease @embl #EESAgeing https://www.embl.org/about/info/course-and-conference-office/events/ees23-04/
Thiago Carvalho
boosted
In #JapaneseFolklore hyakki yagyo is the night parade of one hundred demons. On inauspicious nights, all the #yokai, ghosts and other supernatural creatures parade through the streets of #Japan, singing and dancing wildly. For anyone foolish enough to be outside, or even to peek out of their window, an encounter with the pandemonium of the dreaded night parade will result in death, or being spirited away by malevolent yokai.
#folklore #japodon #hyakkiyagyo @folklore
🎨Yuko Shimizu
Thiago Carvalho
boosted
I'm always amazed at the talent of past dissection drawings by microscope-biologists: this bee by Pfurtscheller dates to 1902.
Thiago Carvalho
boosted
Our next term "Stem #Cells" starts with S. Dr. Simon Haas, head of a #BIH junior #research group within the joint focus area “Single-Cell Approaches to Personalized Medicine” launched by the Berlin Institute of Health (BIH), @MDC_Berlin and #Charité – Universitätsmedizin #Berlin does research on stem #cells and has recently even received a Starting Grant from the European Research Council (ERC) for his work. It will total €1.5 million over five years: https://www.bihealth.org/en/notices/wie-sich-leukaemiezellen-und-immunzellen-begegnen-erc-starting-grant-fuer-simon-haas
@theonlylabever Welcome to the Pleistocene!
Thiago Carvalho
boosted
Ok, not sure where this will lead. I am here to connect with #scientists interested in #immunology (and far beyond) and shamelessly promote the results of the hard working students, I am privileged to supervise in #theonlylabever - I may occasionally post non-science content.
Thiago Carvalho
boosted
#Advent Day19: #Drosophila busckii, in the subgenus Dorsilopha (ha!), is the last of our global human commensals. A charismatic looking fly, I often find Dbus in compost heaps, and it is unusual in liking rotting potatoes & brassicas https://link.springer.com/article/10.1007/BF00345697 , and once—famously—a formalin-preserved fish http://www.drosophila.jp/jdd/class/070201/07020102.pdf ). Busckii’s love of rot has even implicated it as a horticultural vector of the generalist plant (and fly) bacterial pathogen Erwinia carotovora https://pure.knaw.nl/ws/portalfiles/portal/9139050/Sommen_NEV.pdf
"We observed a significant increase in the expression of IL-31RA, but not its cognate ligand IL-31 during house dust mite- and Schistosoma mansoni soluble egg antigen-induced allergic asthma. In support of this, IFN-γ and Th2 cytokines, IL-4 and IL-13, upregulated IL-31RA but not IL-31 in airway smooth muscle cells (ASMC). Importantly, the loss of IL-31RA attenuated AHR but had no effects on inflammation and goblet cell hyperplasia in allergic asthma or mice treated with IL-13 or IFNγ."
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
