This is just a ludicrous policy. Think of it this way: what would happen if Australia, Japan, South Africa or India asked for the lab notebooks of American researchers every three months? This is ill-considered policy, which will dissuade global health research. This is on NIH and HHS. They put this in place. They need to fix it.
@halama_immuno @physorg_bot @gpollara Absolutely - but there are some very interesting details here, like this one "For instance, we find that bats have either lost CARD8 or have a CARD8 protein that is antagonized, rather than activated, by coronavirus 3CLpro cleavage."
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002144
@dmaseda Thank you Damian
June 9, 1891, French painter Paul Gauguin arrives in Papeete, Tahiti - a landscape of Tahiti with #volcano 🌋🖌️
AstraZeneca invests in Tregs
"One of the most promising UK biotech start-ups, Quell Therapeutics, has signed a research collaboration and licensing deal with AstraZeneca to develop treatments for two autoimmune diseases."
https://www.ft.com/content/92b0e9d5-22c1-4ddd-b135-52de8e200a48
"As of January 2023, the estimated prevalence of long Covid among people in the United States who had had acute infection was 11%. According to guidance released in August 2021 by the Department of Health and Human Services and the Department of Justice, long Covid can be considered a protected disability under the Americans with Disabilities Act (ADA) and under other disability-antidiscrimination mandates (such as Section 504 of the Rehabilitation Act and Section 1557 of the Affordable Care Act)."
https://www.nejm.org/doi/full/10.1056/NEJMp2302676?query=featured_home
My Clinical Pipeline column for Nature Medicine this week examines the state of Sarepta's new gene therapy for Duchenne muscular dystrophy application at the FDA. Whatever its final efficacy turns out to be, the general strategy behind the therapy, an engineered micro-dystrophin is very clever.
It was inspired by the case of a 61 year old patient who had a deletion of almost half of his dystrophin gene and was still alive and walking. Here's that ref, from 1990:
https://www.nature.com/articles/343180a0
And here's my column:
@halama_immuno @physorg_bot @gpollara Absolutely - but there are some very interesting details here, like this one "For instance, we find that bats have either lost CARD8 or have a CARD8 protein that is antagonized, rather than activated, by coronavirus 3CLpro cleavage."
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002144
@physorg_bot This trip-wire has been around for awhile already... @gpollara @cyrilpedia
Referenced link: https://medicalxpress.com/news/2023-06-immune-wire-covid-.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-06-immune-wire-covid-.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1666867708095234049#m
RT by @physorg_com: Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://journals.plos.org/plosbiology/article https://medicalxpress.com/news/2023-06-immune-wire-covid-.html
'These biofilms encase immune cells and establish a high local concentration of a secreted hemolysin to kill the immune cells before the biofilms disperse in a c-di-GMP-dependent manner.'
'These biofilms encase immune cells and establish a high local concentration of a secreted hemolysin to kill the immune cells before the biofilms disperse in a c-di-GMP-dependent manner.'
Large scale proteomic studies create novel privacy considerations | https://www.nature.com/articles/s41598-023-34866-6#additional-information #proteomics
The US Supreme Court is a farce. It should no longer be supreme.
"The US Supreme Court has gutted federal protection for wetlands — now what?"
As CSHL is the home of
@biorxivpreprint, I've put together a @preLights 'preList' of #preprints mentioned during #cshlsymp23:
https://prelights.biologists.com/prelists/cshl-87th-symposium-stem-cells/
'A global comparison of the long-read data from young and aged mice showed an age-associated increase in the expression of noncoding transcripts, including IgV pseudogenes, lncRNAs and transcripts with retained introns (Supplementary Fig. 7). This is consistent with observations that an increased frequency of intron retention has been identified as a signature of ageing in fruitfly, mouse and human'
We’re looking for African researchers keen to represent their community on our editorial board.
Does this sound like you? Apply to join our Board of Reviewing Editors! https://elifesciences.org/inside-elife/5b024d5b/elife-latest-applications-open-for-new-reviewing-editors-in-africa?utm_source=mastodon&utm_medium=social&utm_campaign=organic
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com