Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
'Together, these results demonstrate that host cGAS–STING senses T. cruzi infection, enhancing parasite growth at the site of entry, and contributes to acute-phase parasite restriction in the heart, a major site of tissue damage in chronic T. cruzi infection.'
#immunology #InnateImmunity #HostPathogen
Thiago Carvalho
boosted
'Sharing your setbacks can seem counter-intuitive, especially when these events stir up feelings of shame and inadequacy. But that’s why Geszvain shares her experiences and encourages her students to do the same.'
Thiago Carvalho
boosted
'Coinciding with rising awareness about the risks of R.S.V., there are finally tools available to prevent severe infections in both infants and older adults.'
#Infection #immunology #vaccines #MonoclonalAntibody #RSV
Thiago Carvalho
boosted
AHR is also highly active in endothelial cells lining BV in 🫁 .
🫁 barrier between the body & the air outside is only made up of 2 layers, one of endothelial cells and one of epithelial cells to allow oxygen to enter & the barrier also has to be kept strong against pollution or 🦠 &bacteria.
https://www.crick.ac.uk/news/2023-08-16_research-finds-that-molecules-in-vegetables-can-help-to-ease-lung-infection
'Lembrei-me desta teoria de Thomas Merton a propósito do pacote Mais Habitação e das reações que provocou nos partidos à direita. Quem avaliar a proposta através das reações destes partidos e de outras organizações justamente conotadas com princípios de direita chega à conclusão que se trata de um diploma de esquerda radical, marxista ou comunista.'
https://www.publico.pt/2023/08/23/opiniao/opiniao/pacote-habitacao-nao-nada-socialista-2060948
Thiago Carvalho
boosted
Diversity and Evolutionary History of Ti Plasmids of “tumorigenes” Clade of Rhizobium spp. and Their Differentiation from Other Ti and Ri Plasmids https://doi.org/10.1093/gbe/evad133 #science #evolution #biology #genome #evolgen_paper
'The extrinsic incubation period (EIP), defined as the time it takes for malaria parasites in a mosquito to become infectious to a vertebrate host, is one of the most influential parameters for malaria transmission but remains poorly understood.'
Thiago Carvalho
boosted
Happy (or not?) #MicroscopyMonday!
I made a chart out of all the amoeba faces I've found to put on the lab fridge. Unfortunately, happy faces are not an observable phenotype for Naegleria.
Thiago Carvalho
boosted
"The tree which moves some to tears of joy is in the eyes of others only a green thing which stands in the way... As a man is, so he sees."
On this day in 1799, Blake wrote his most beautiful letter – a timeless defense of the creative imagination https://t.co/wRFV1IRigC
'The elucidation of the lipid metabolic pathways that promote innate immune memory contributes to our understanding of trained immunity and may help identify therapeutic tools and targets for the modulation of innate immune responses.'
#immunology #InnateImmunity #Preprint
'Meanwhile, scientific interest in vagus nerve stimulation is exploding, with studies investigating it as a potential treatment for everything from obesity to depression, arthritis and Covid-related fatigue. So, what exactly is the vagus nerve, and is all this hype warranted?'
"An influential expert panel has given its highest recommendation to an expanded menu of H.I.V. prevention strategies for adults and adolescents, a move that will require private insurers to cover the drugs without a co-pay or deductible under the Affordable Care Act."
#HIV #publichealth
Thiago Carvalho
boosted
Sabrina Holland and Gianluca Gallo revisit the relationship between actin dynamics and energy homeostasis in growing neurons, discovering that cytoskeletal dynamics do not impose an energy drain.
Highlight: https://journals.biologists.com/jcs/article/136/16/e136_e1602/325934/Revisiting-actin-dynamics-and-energy-homeostasis
Article: https://journals.biologists.com/jcs/article/136/16/jcs261356/325925/Actin-cytoskeletal-dynamics-do-not-impose-an
#CellBiology #cytoskeleton #energy #actin
"On Tuesday, an international team announced in the journal Cell that they had identified a potential new antibiotic lurking unnoticed in the sandy soil of North Carolina. The compound, called clovibactin, employs an unusual method of killing bacteria that makes it tough for targets to develop resistance. While clinical trials in humans are several years away, the finding is a glimmer of hope in an increasingly drug-resistant world."
#microbiology #antibioticresistance #antibiotics #drugdevelopment
https://www.ft.com/content/a8d62524-3f3f-4d61-a27f-a689a13f9232
Thiago Carvalho
boosted
"With these questions growing in urgency, and answers elusive, a group of scientists has recently called for AI companies to start investing seriously in consciousness research1.
Against this background, we thought it would be a good moment to put some of the big questions in this area to some leading experts on consciousness and/or higher cognition in humans and other animals."
https://www.cell.com/current-biology/fulltext/S0960-9822(23)00852-7
Thiago Carvalho
boosted
“Just like Omicron was a little out of left field, this BA.2.86 is little out of left field,” says Ashish Jha, a public-health researcher at Brown University in Providence, Rhode Island, and the former White House COVID-19 Response Coordinator. “There is enough here to get us all to start paying attention.”
#covid19 #covid #sarscov2 #publichealth
Thiago Carvalho
boosted
This library looks amazing:
"Con 4.000 metros cuadrados, la sensación de amplitud es mayor en el interior que en el exterior. Y facilita crear puntos de mayor o menor intimidad gracias a espacios con cortinas."
Thiago Carvalho
boosted
Propaganda from the wealthy has not JUST promoted neoliberal "markets" over humanity and democracy.
It has also misinformed the public about what government itself is.
In a surprising twist, another MiniMussolini turns out to be a crook.
'Mr Bolsonaro, 68, has become ensnared in a series of investigations into fraud and election tampering that have already landed some of his closest allies in jail and that, over the past several weeks, appear to be closing in on him.'
https://www.nytimes.com/2023/08/22/world/americas/bolsonaro-brazil-arrest-watches.html
Thiago Carvalho
boosted
'Sharing widely read content, by itself, isn’t a problem. But it becomes a problem when attention-getting, controversial content is prioritized by design.'
cc @joanagsa
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
