'Researchers in China have found evidence suggesting that 930,000 years ago, the ancestors of modern humans suffered a massive population crash. They point to a drastic change to the climate that occurred around that time as the cause.'
You'll never guess what happened next.
"The goal was to generate agreement on legally binding shared principles before the next pandemic, with sufficient authority to promote engagement at the highest levels of government.
That was nearly two years ago."
https://www.ft.com/content/17fec31b-909e-4bea-8c0f-cc3e2a597cd8
'However, when he tested these high-molecular-weight polysaccharides in animal models, he was quite disappointed to find that they were not immunogenic. Confident that he had the solution, he then decided to inject himself with the high-molecular-weight polysaccharide and made the seminal discovery that the vaccination induced a strong immune response.'
'Recent description of the developmental stages along the differentiation trajectory of T cell exhaustion has provided insight into past immunotherapeutic success and future opportunities. Here, we discuss the hallmarks of distinct developmental stages occurring along the path to T cell dysfunction and the impact of these discrete CD8+ T cell fates on cancer immunotherapy.'
#Immunology
'In an ideal world, the authors would engage collaboratively with journals and those who have raised concerns on determining how to adjust the scientific record to account for these problems, and journals would post updates quickly. This rarely happens, and that needs to change.'
https://www.latimes.com/opinion/story/2023-08-31/stanford-marc-tessier-lavigne-science-retractions
'Those suffering from long Covid often feel forgotten, in part because the medical establishment is struggling to define, let alone treat, this new condition. As Jana Javornik, a lecturer at Leeds university who suffers from long Covid, told the FT a few months ago, “We are all neglecting that long Covid is not rare and it is a health crisis.”'
#COVID #LongCovid
https://www.ft.com/content/5f547155-787c-4c60-966d-50b48d908a2a
'Poland is also the E.U.’s biggest operator of mink farms. One obvious worry is whether the minks are getting sick with H5N1 and mink meat is somehow contaminating the food chain and eventually reaching the cats.'
https://www.nytimes.com/2023/08/31/opinion/bird-flu-h5n1.html
Modern ‘Sixth Mass Extinction’ Event Will Be Worse Than First Predicted | Biological Reviews
by @GrrlScientist via @ForbesScience / @Forbes
#biodiversity #extinction https://www.forbes.com/sites/grrlscientist/2023/07/19/modern-sixth-mass-extinction-event-will-be-worse-than-first-predicted/
In 2002, there was a vision to promote & strengthen the genomic sciences in Mexico sustainably through the establishment of an Undergraduate Program in Genomic Sciences. Twenty years later, this vision has impacted science in Mexico and the world. #LCG20🇲🇽
https://www.gaceta.unam.mx/veinte-anos-de-la-licenciatura-en-ciencias-genomicas/
'Earlier, the Colada boys had found evidence of fraud in a paper co-authored by Duke professor Dan Ariely. The real juicy bit? There’s a paper written by both Ariely and Gino in which they might have independently faked the data for two separate studies in the same article. Oh, and the paper is about dishonesty.'
https://www.experimental-history.com/p/im-so-sorry-for-psychologys-loss
'However, when he tested these high-molecular-weight polysaccharides in animal models, he was quite disappointed to find that they were not immunogenic. Confident that he had the solution, he then decided to inject himself with the high-molecular-weight polysaccharide and made the seminal discovery that the vaccination induced a strong immune response.'
Ancient scorpion trapped in amber
#FossilFriday https://www.scielo.br/j/jvatitd/a/NGR7dTyggrnGBSxvQ6pdSJs/#
@marcelsalathe Bravo
Ministers claimed today that the collapsing school buildings scandal only emerged "over the summer".
In reality schools first started warning about the problem five whole years ago
You'll never guess what happened next.
"The goal was to generate agreement on legally binding shared principles before the next pandemic, with sufficient authority to promote engagement at the highest levels of government.
That was nearly two years ago."
https://www.ft.com/content/17fec31b-909e-4bea-8c0f-cc3e2a597cd8
'However, the contribution of stromal cells of the hematopoietic niches in the control of HSPC asymmetric divisions remains unknown. Using polyacrylamide microwells as minimalist niches, we show that heterotypic interaction with osteoblast promotes asymmetric division of human HSPC.'
#Preprint
Prisca from Jersey deserves its own Springsteen ballad!
"These include the oldest undisputed fossil bee, Cretotrigona prisca, from New Jersey amber, which was recovered far outside of its lineage’s present-day range."
https://www.cell.com/current-biology/fulltext/S0960-9822(23)00912-0
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com