Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
'Comprehensive studies of 14 complex structures of Mpro mutants with drugs or substrate revealed that mutations at the S1 and S4 subsites significantly decreased inhibitor binding, while mutations at the S2 and S4’ subsites unexpectedly increased protease activity.'
Thiago Carvalho
boosted
Chemotherapy awakens dormant #cancer. #Tumor stromal organoid & murine #BreastCancer model show that #chemotherapy injures stromal cells; this injury in turn invokes proinflammatory #cytokine signaling and can awaken dormant cancer cells #PLOSBiology https://plos.io/3RjsGoQ
Thiago Carvalho
boosted
“Two full-time workers earning Tokyo’s minimum wage can comfortably afford the average rent for a two-bedroom apartment in six of the city’s 23 wards. By contrast, two people working minimum-wage jobs cannot afford the average rent for a two-bedroom apartment in any of the 23 counties in the New York metropolitan area.” https://www.nytimes.com/2023/09/11/opinion/editorials/tokyo-housing.html
Thiago Carvalho
boosted
Burden of tuberculosis among vulnerable populations worldwide: an overview of systematic reviews
> The burden of tuberculosis is substantially higher among vulnerable populations than general populations, suggesting a need for improved integration of these groups, including dedicated efforts for their identification, targeted screening and prevention measures, as well as treatment support.
#IDMastodon #MedMastodon #infectiousdiseases #medicine #TB #tuberculosis
Thiago Carvalho
boosted
"We don't need to visit Egypt, we've got Suez at home."
Suez at home:
"But this upbeat narrative of scientific discovery is missing an important piece: Mojsov herself. She, too, was at MGH in the 1980s and published early key papers on GLP-1. She later fought, successfully, to be added to crucial patents that initially omitted her as a co-inventor."
"Here, we identify a stem cell-like CD7+ monocyte subpopulation accumulating in the bone marrow (BM) of mice and humans that experienced dieting-induced weight loss. Adoptive transfer of CD7+ monocytes suppresses weight regain, whereas inducible depletion of CD7+ monocytes accelerates it."
#Metabolism #Immunology
Thiago Carvalho
boosted
Postdoctoral Position in Structural Virology at Johns Hopkins
Chang Liu Lab
Come join us at @JohnsHopkins as a structural virology postdoc
See the full job description on jobRxiv: https://jobrxiv.org/job/chang-liu-lab-27778-postdoctoral-position-in-structural-virology-at-johns-hopkins/?feed_id=58659
#ScienceJobs #hiring #research
Baltimore #UnitedStatesUS #Postdoctor...
https://jobrxiv.org/job/chang-liu-lab-27778-postdoctoral-position-in-structural-virology-at-johns-hopkins/?feed_id=58659
Thiago Carvalho
boosted
Universities reliant on overseas students - report
https://www.bbc.co.uk/news/education-66786377?at_medium=RSS&at_campaign=KARANGA
'Têm uma intolerância visceral a qualquer restrição ao direito de propriedade e ao direito a fazer negócios – mesmo que estejamos a falar de cidadãos estrangeiros com condições socioeconómicas esmagadoras em comparação a quem vive dos rendimentos do seu trabalho em Portugal. O direito de propriedade e a liberdade económica não são como o direito à vida. Podem, e devem se for preciso, conhecer restrições.'
Thiago Carvalho
boosted
Proteomic biomarker evaluation using antibody microarrays: association between analytical methods such as microarray and ELISA | https://academic.oup.com/labmed/advance-article-abstract/doi/10.1093/labmed/lmad083/7268787?redirectedFrom=fulltext&login=false #proteomics
Thiago Carvalho
boosted
Google's Chrome browser is now a thin candy shell of browser interface around a full-time surveillance engine and personal data monetization machine. Find a better browser, folks.
Thiago Carvalho
boosted
Former Austrian foreign minister emigrates to Russia to head think tank. 🙄 https://www.euractiv.com/section/politics/news/former-austrian-fm-emigrates-to-russia-to-head-think-tank/
'If the F.D.A. ordered their removal, a trade group warned that numerous popular products — including Tylenol, Mucinex and Benadryl cold and flu remedies — might become unavailable as companies race to reformulate them.'
'Three hospitals declined to provide the procedure, she said. At the third, “they said, ‘We can’t touch you unless you’re like crashing in front of us,’” Ms. Statton, 26, said in an interview. The hospital’s only suggestion, she said, was “we should wait in the parking lot until I was about to die.”
Thiago Carvalho
boosted
"Musk is losing, too. Every day, he becomes a bigger punchline. Someday, the outsize tab he’s run trying to keep hold of Twitter will come due. I hope that when it happens, the expats of Twitter will have settled in a new place where we can watch his downfall together." Andrea Grimes, Dame Magazine
https://www.damemagazine.com/2023/09/12/when-twitter-died-so-did-independent-journalism/
Thiago Carvalho
boosted
My latest for Nature Medicine: transgenic pig organs for xenografts transplanted into brain-dead human recipients.
Kidney & heart transplants at NYU, UAB & Maryland. They've succeeded in overcoming hyperacute rejection, but many challenges remain.
Thiago Carvalho
boosted
The team also modeled the probability of adverse events from mRNA vaccination, direct medical costs from COVID-19, and productivity loss from COVID-19, cost of medications to treat COVID-19, and the cost of vaccination. I will say that the cost of hospitalization from...
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Thiago Carvalho
boosted
Dr. Ruth Link-Gelles will now present on the latest vaccine effectiveness data. These will focus on medically-attended illnesses.It is important to understand that all the data reflect the INCREMENTAL benefit of vaccination in a population...
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Thiago Carvalho
boosted
The Fish Pathogen “Candidatus Clavichlamydia salmonicola”—A Missing Link in the Evolution of Chlamydial Pathogens of Humans https://doi.org/10.1093/gbe/evad147 #science #evolution #biology #genome #evolgen_paper
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
