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My latest for @thenation. We know what good policies look like, BUT we are terrible at figuring out how to keep them, make them flourish. Building on the idea of policy "feedback loops" from Jamila Michener at Cornell, Connie Razza at Social and Economic Justice Leaders Project. This is one of the most critical lessons we have not learned yet in public health.

thenation.com/article/society/

Sidney Powell pleads guilty in the election interference case and is now cooperating with prosecutors against Trump

Kraken cracked. 🇺🇸

Individual rare diseases are... rare. But taken together, they affect a significant fraction of the population. We need to develop a sustainable economic model for gene therapy.

"As a result, while the number of people eligible for any single gene therapy might be small, the total number of people eligible across all of them could soon be significant. Annual spending on gene therapies could increase from $5.15 billion 2020 to $25.3 billion in 2026."

bloomberg.com/opinion/features

"It's important to remember that the 'drugs' aren't just the pills we stash in our medicine cabinets. Ask yourself this: is it really acceptable that we only bothered to test sex differences for general anesthesia in 1999? Turns out women wake up faster than men, regardless of their age, weight or the dosage they've been given."

From Cat Bohannon's highly recommended book Eve.

Colares, near Sintra, has very special wines - the vines grow on the beach.
This one was delicious.

Já nas livrarias!

Novo livro do José Eduardo Agualusa, edição da Quetzal e capa de Rui Rodrigues com ilustrações minhas.

Vidas e Mortes de Abel Chivukuvuku.

Um espanto.
Capa mais bonita não há :)

nature.com/articles/s44161-023
Covid increases the risk of heart attacks. A mechanism that has recently been supported, at least in some people affected, is promoting coronary atherosclerosis and plaque instability

"El nuevo subtipo de virus de la gripe aviar está por todas partes. El equipo de Dhanasekaran ha investigado la evolución del patógeno y alerta este miércoles de que “el epicentro” de la crisis se ha desplazado desde Asia hacia Europa y África."

elpais.com/ciencia/2023-10-18/

New article! Read Gene regulatory network reconstruction: harnessing the power of single-cell multi-omic data nature.com/articles/s41540-023 in npj SBA

'Before it released the A.I. chatbot ChatGPT last year, the San Francisco start-up OpenAI added digital guardrails meant to prevent its system from doing things like generating hate speech and disinformation. Google did something similar with its Bard chatbot.
Now a paper from researchers at Princeton, Virginia Tech, Stanford and IBM says those guardrails aren’t as sturdy as A.I. developers seem to believe.'

nytimes.com/2023/10/19/technol

"In this review, we discuss key advances that highlight mechanisms used by T cell subsets to populate the epidermis and dermis, maintain skin homeostasis, and regulate wound repair."

journals.aai.org/jimmunol/arti

Pfizer more than doubles price of lifesaving Covid-19 medication Paxlovid as US transitions out of pandemic phase | CNN

cnn.com/2023/10/18/health/pfiz

'Dr. Marc Sala, co-director of the Northwestern Medicine Comprehensive Covid-19 Center, said fatigue has become the dominant complaint from his patients. That could be because Covid symptoms are becoming milder overall — he no longer regularly sees patients with severe respiratory damage, and so fatigue has come to the forefront, he said. It’s also possible that fatigue could be a more common symptom with the newer variants, he said.'

nytimes.com/2023/09/27/well/li

@marksquires It's under perpetual threat from real estate developers, so fingers crossed.

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