Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
"To tackle the climate crisis, we need an economy-wide transformation which puts ambitious objectives, like climate targets, at the centre of our economic and fiscal strategy. We need long-term, patient and mission-orientated finance. Governments — and especially public development banks — are critical in providing the kind of far-sighted long-term funding that traditional financiers shy away from."
https://www.ft.com/content/7b509fb6-4616-4461-b94f-b2332bc28c76
"Participation in research experiences and internships may improve graduation rates and persistence in science, technology, engineering, and mathematics (STEM) among undergraduates, yet very little is known about the benefits of these activities for community college students. To fill this gap, we collected survey and interview data from 43 individuals who completed the Community College Internship (CCI) at Lawrence Berkeley National Laboratory (LBNL)."
#Preprint
Abby who?
"Here we present the ‘zebrafish single-cell atlas of perturbed embryos’: single-cell transcriptomic data from 1,812 individually resolved developing zebrafish embryos, encompassing 19 timepoints, 23 genetic perturbations and a total of 3.2 million cells."
Thiago Carvalho
boosted
"Although type 1 conventional dendritic cells (cDC1s) were not required for initial priming of CD4+ T cells, cDC1s were required for CD4+ T cell expansion and gut homing. cDC1s were also a major source of IL-12 that was not required for priming but promoted full differentiation of CD4+ T cells and local production of IFN-γ. Together, these studies reveal distinct roles for cDC1s in shaping CD4+ T cell responses to enteric infection: first to drive early expansion in the mesLN and second to drive effector responses in the gut."
#InfectionImmunity #Immunology #MucosalImmunology #parasitology #Preprint
Thiago Carvalho
boosted
I love this set.
Colin Donnell as Roy Scheider, Ian Shaw as Robert Shaw, and Alex Brightman as Richard Dreyfuss in The Shark Is Broken at the John Golden Theatre, 2023
Photo: Matthew Murphy.
#SetDesign #theater #theaterarts
https://www.nybooks.com/online/2023/11/14/three-men-and-a-shark-jaws/
Thiago Carvalho
boosted
'Our results show that neutralizing antibodies in children possess similar genetic features compared to antibodies identified in adults, with multiple antibodies from children belonging to previously established public antibody clonotypes in adults.'
Thiago Carvalho
boosted
"Inevitably, people have suggested that pulling a move to restore Cameron to the frontline is like rearranging the deckchairs on the Titanic, but arguably that doesn’t really cover it. This is not like shifting the deckchairs in 1912, an hour after the iceberg had hit, but like doing it now, in 2023, when David Cameron’s form has been largely consumed by molluscs, and fish have been swimming in and out of his cavities, along with the various Treasury committee members who in 2021 probed his lucrative lobbying of ministers on behalf of the now-collapsed Greensill Capital. These days, he’s arguably more reef than man."
https://www.theguardian.com/commentisfree/2023/nov/14/failure-david-cameron-libya-failed-state
"Javier Milei, el candidato presidencial de la ultraderecha argentina, ha puesto patas para arriba los consensos que desde hace 40 años mantienen a flote la democracia argentina. Pretende terminar con la educación y la salud públicas, desfinanciar universidades y se opone a las leyes de aborto y el matrimonio igualitario."
Thiago Carvalho
boosted
“Pela boca morre o peixe”. Prato falante.
Glazed #stoneware by @hunchbacksociety
#proverbs #proverbios #ceramics #plate #pottery #artgallery #artstagram
Thiago Carvalho
boosted
A new issue of the Journal of the History of Economic Thought is now online
#TBT, from early 2022:
The #EMBOpodcast with immunologist Matteo Iannacone, & neuroscientist Katrin Franke.
#Immunology #Neuroscience #SciComm #SciencePodcast
https://www.embo.org/podcasts/embo-young-investigators-past-and-present/
Thiago Carvalho
boosted
“Are ribosomes guarding mitochondria during starvation? The fascinating cryo-EM/ET images provided in this preprint suggest that they might be!”
preLight by Barbora Knotkova covering beautiful work from the labs of Simone Mattei & Ahmad Jomaa – take a look! 👀
#preLight 👉 https://prelights.biologists.com/highlights/hibernating-ribosomes-tether-to-mitochondria-as-an-adaptive-response-to-cellular-stress-during-glucose-depletion/
#preprint #ribosomes #mitochondria #CryoEM #CryoET #microscopy
"According to the V.A., the Million Veteran Program is the largest such database in the world. It includes not only genetic information but also is linked to the department’s electronic medical records and even contains records of diet and environmental exposure."
https://www.nytimes.com/2023/11/15/health/million-veterans-database-va.html
Thiago Carvalho
boosted
Meta is allowing ads containing conspiracy theories about the last US election on Insta and Facebook. I imagine this significantly advantages Trump.
https://newrepublic.com/post/176938/meta-screw-up-2024-election-ads-rigged-lie
Thiago Carvalho
boosted
'The private equity industry is facing a “shakeout” that could result in painful losses for investors who piled into the sector without properly understanding the risks of holding illiquid assets, according to the chief investment officer of one of the world’s largest charitable foundations.'
https://www.ft.com/content/216e1829-a92c-43f7-8dc3-d7e99f68f18c
Thiago Carvalho
boosted
... no amount of investigation of another person’ s neural processes by means of fMRI will allow us to inspect his reasoning or what he is thinking.
Bennett, M. R.; Hacker, P. M. S.. Philosophical Foundations of Neuroscience (p. 107). Wiley. Kindle Edition.
Not great. Gantenerumab is a monoclonal antibody against aggregated Aβ:
"Among persons with early Alzheimer’s disease, the use of gantenerumab led to a lower amyloid plaque burden than placebo at 116 weeks but was not associated with slower clinical decline."
#alzheimers
https://www.nejm.org/doi/full/10.1056/NEJMoa2304430?query=featured_home
Thiago Carvalho
boosted
#IDMastodon #PublicHealth Data from the English Surveillance Programme for #Antimicrobial Use & Resistance (ESPAUR) show a 11.7% increase in patient episodes of #bloodstreaminfections (https://link.springer.com/article/10.1007/s00134-020-05950-6 ) and/or fungemia from 2018 to 2022. The most common causes of monomicrobial BSIs were #Escherichiacoli (20.9%)& #staphylococcusaureus (7.7%). The incidence of Candidemia increased by 22.7%…
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
