"Here, by studying 98 tissues from 27 deceased transplant organ donors we demonstrate that despite representing less than 5% of circulating Tregs, fully functional, thymically derived CD8+FOXP3+ Tregs are highly enriched in human tissues particularly in non-lymphoid tissues and bone marrow, where they reside as CD25lo/-CD8+CD69+CD103+TLR9+HELIOS+FOXP3+ Tregs."
#Preprint #Immunology
"In Ireland, seeking work has often meant moving to England. The early songs of the Pogues documented what awaited there in the early 1980s — a time when it was, to put it mildly, challenging to be Irish in London. Irish people had been portrayed variously as buffoons, insurrectionists and animals in the British media since Victorian times, and ethnic hate and discrimination were prevalent well into the 1980s. The conflation of all Irish with the Irish Republican Army led to miscarriages of justice like the Guildford Four, the Birmingham Six and the Maguire Seven, who were wrongly imprisoned for I.R.A. bombings in the 1970s."
Shane MacGowan, right, and Spider Stacy of the Pogues in 1987.
Photo Credit: Stephen Parker/Alamy
https://www.nytimes.com/2023/12/24/opinion/fairytale-new-york-the-pogues.html
Hello!
I'm a synthetic developmental biologist at The University of Edinburgh.
I'm interested in understanding how cells influence their neighbours in mammalian models of #DevBio and disease.
I use #SynBio to identify neighbours of cells of interest (e.g. healthy neighbours of mutant cells), and to engineer cell behaviour in response to these interactions.
I do this in pluripotent #StemCells and their derivatives.
I look forward to keeping up with everyone's cool research!
"La respuesta oficial ha sido la extorsión descarada a los más pobres: a aquellos que no estén de acuerdo con los cambios y decidan salir a la calle se les amenazó con quitarles la ayuda de la que dependen, en muchos casos, para comer."
https://elpais.com/opinion/2023-12-24/el-desguace-argentino.html
“Mortality and hospitalisation rates [for JN. 1] are not the explosive rates we saw during the Delta wave, but we’re definitely seeing an increase,” said Malvestutto. He said a jump in infections was also to be expected with the return of a regular flu season and the ongoing respiratory syncytial virus, or RSV, at a time of year when crowds gather indoors.'
https://www.ft.com/content/7d4b3629-3d0c-45bc-8aa8-eb88ab9b4ce9
'It involves a debut author with a lot of buzz, lies, clumsy alibis, “review bombing,” a long and sordid confession — and, of course, Goodreads. Because whenever there is a meltdown in publishing, Goodreads, the Amazon-owned site that bills itself as “the largest site for readers and book recommendations,” is reliably at the center of it.'
https://www.nytimes.com/2023/12/24/opinion/goodreads-books-reviews.html
Argentine Unions Announce Mobilizations Against Milei's Decree
> The trade unions will demand the repeal of the DNU (Urgency and Necessity Decree). On the same day, the trade unionists will make their legal submissions and protect against the measures promoted by the Government.
https://www.telesurenglish.net/news/Argentine-Unions-Announce-Mobilizations-Against-Mileis-Decree-20231224-0002.html #Argentina
The gift that keeps on giving:
"Os governos que saíram vencedores da II Guerra Mundial não deram de imediato atenção à ideia de criar uma carta de direitos para a Humanidade, interessados que estavam em discutir esferas de influência e em arquitetar a Carta das Nações Unidas de maneira a garantir os seus poderes de veto"
Great opportunities for software and data science to work at the World Health Organization!
We especially encourage people from underrepresented demographics and backgrounds to apply!
Please do share the information broadly, gladly with support networks and associations.
My team is looking to fill three staff positions based at the WHO Hub for Pandemic and Epidemic Intelligence in Berlin, Germany. We support public health intelligence with training, research, and software. 1/
Hurrah!
The National: "UK left out as EU agrees to ‘landmark’ cross-continent transport plans."
#BrexitBonus #BrexitDividend #Brexit
https://www.thenational.scot/news/24009783.uk-left-eu-agrees-landmark-transport-plans/?ref=psapp
John Waters’ Hand-Made, Oddball Christmas Cards: 1964-Present
https://www.openculture.com/2023/12/john-waters-hand-made-oddball-christmas-cards-1964-present.html
'Measles cases continued to pop up here and there in the densely populated city in 1989 and 1990 — as is common with highly contagious infectious diseases. But measles never managed to get a firm grip on any particular neighborhood or community in that two-year period, in part because the vaccination rate among the overall population was reasonably good. That all changed once the illness made its way to the Faith Tabernacle school.'
https://www.phillymag.com/news/2021/03/20/philadelphia-measles-outbreak-1991/
@ajroach42
I have a set of early 20th century engineering textbooks on steam engines, including:
Stirling: A Book on Steam for Engineers, 1906.
In remarkable condition, including color diagrams, like this one. This is my top candidate for a book scanning project!
Well, I don't like them. They wet their nests.
"Huxley wrote extensively for popular audiences, frequently appeared on radio and television and even directed an Oscar-winning wildlife film, The Private Life of the Gannets."
"La respuesta oficial ha sido la extorsión descarada a los más pobres: a aquellos que no estén de acuerdo con los cambios y decidan salir a la calle se les amenazó con quitarles la ayuda de la que dependen, en muchos casos, para comer."
https://elpais.com/opinion/2023-12-24/el-desguace-argentino.html
"These researchers must be crazy. Several Czechs also won the Ig Nobel Prize" https://www.idnes.cz/technet/veda/nobelova-cena-ig-jaroslav-flegr-vyzkum-oceneni-veda.A231102_140051_veda_dyn
@garyackerman If only Albert King were still around to put this to song.
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com