Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
"Thompson was arguing against both the conservative view of class relations as describing “the harmonious coexistence of groups performing different ‘social roles’” and a form of economic determinism that imagines, as he put it later in an interview, that “some kind of raw material like peasants ‘flocking to factories’” could be “processed into so many yards of class-conscious proletarians”. For Thompson, the working class “made itself as much as it was made”. This idea of agency, of people, even in the most inauspicious circumstances, possessing the capacity to act on the world was central to his life work."
Thiago Carvalho
boosted
What a legendary historian tells us about the contempt for today's working class | Kenan Malik
'Wednesday, Biogen said it's pulling all efforts from the first-of-its-kind anti-amyloid beta therapy to focus on Leqembi, its Eisai-partnered newer medicine, and its pipeline candidates. The newer drug, Leqembi, won a full FDA approval early last year, making the partners' marketing efforts on the therapy much simpler than was the case with Aduhelm.'
Thiago Carvalho
boosted
"Overall, these data demonstrate that IL-15C treatment, via its induction of IL-10 from NK cells, modulates the dysregulated inflammation during Plasmodium infection to promote Tfh differentiation & Ab generation, correlating with improved survival from reinfection."
#Plasmodium #Malaria #InfectionImmunity #immunology
Thiago Carvalho
boosted
Not great, but moving in the right direction:
"Esta foi a primeira vez em vários meses que a curva começou a inverter, registando-se um aumento (de 37% para 42%) dos inquiridos que defendem que Portugal deve acolher mais pessoas de fora da Europa. Paralelamente, foi também a primeira vez desde maio que a percentagem de inquiridos que se mostra anti-imigração desceu, passando de 61% para 55%."
Thiago Carvalho
boosted
'The feverish pace of deforestation of the Bolsonaro years has slowed, dropping by 33.6 percent during the first six months after Luiz Inácio Lula da Silva—known to all as Lula—was inaugurated president for his third term in 2023. But less has changed than those of us rooting for the survival of planet Earth might like: the local dynamics, the destructive ways of making money from the rainforest, the permissiveness and lawlessness have remained the same.'
https://www.nybooks.com/articles/2024/02/22/the-forest-eaters-banzeiro-okoto-eliane-brum/
Thiago Carvalho
boosted
Without access to a lab, without university support, entomologist Charles Henry Turner (born on this day in 1867) revolutionized our understanding of how intelligence and emotion evolved in his exquisite experiments with bees and ants https://t.co/BD8Ml3MFD1 #BlackHistoryMonth
Thiago Carvalho
boosted
“If you have growing numbers of researchers who are being strongly incentivised to publish just for the sake of publishing, while we have a growing number of journals making money from publishing the resulting articles, you have a perfect storm,” said Professor Marcus Munafo of Bristol University. “That is exactly what we have now.”
Thiago Carvalho
boosted
Cancer knows no age, no gender, no border.
This #WorldCancerDay, we continue to turn the tide by reducing inequalities and making a difference to the lives of everyone affected by cancer.
This week, we proposed a recommendation on vaccine-preventable cancers.
🎗️Notably, it focuses on boosting the uptake of vaccinations against viral infections Human papillomavirus and Hepatitis B that may lead to cancer.
More → https://europa.eu/!H93DpQ
'In Europe — where Wegovy is not yet generally available in public health systems — 80 per cent of sales are paid for personally by consumers, with the remainder reimbursed by health insurance or states. In the US, more than 90 per cent of sales are completely or partially covered by health insurance, the company said.'
https://www.ft.com/content/bbbe8543-263c-4e5b-a567-2ef05f2b3138
"Base editing has arrived on the cellular immunotherapy scene, allowing the simultaneous manipulation of numerous genes—and bringing with it promising proof-of-concept data among the first patients who received the technology."
Ceci n'est pas un spreadsheet.
"A restaurant would not serve you a photo of the meal you ordered. If you have a spreadsheet, why would you save it as an image file? Not being able to copy and paste data or to clearly read it decreases the possibility of curation. Again, this can be solved simply by paying attention to proper formatting."
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002477
Thiago Carvalho
boosted
"We generated mice for the B cell–conditional expression of the most frequent BTG1 mutation [Gln36→His (Q36H)]. Btg1Q36H cells almost completely outcompeted their wild-type counterparts, specifically in the GC. This competitive fitness manifested as a stronger induction of MYC-dependent growth programs."
#immunology
Thiago Carvalho
boosted
"For these reasons, we hypothesize that PTMs could have been selected throughout evolution at the flanks of aggregation-prone regions as an intrinsic factor to protect proteins against aggregation, thus expanding the current repertoire of aggregation gatekeepers."
Thiago Carvalho
boosted
"Fanon wrote at the height of the Cold War, but, with no less prescience, he regarded the East-West struggle as a passing sideshow, of far less consequence than the divisions between North and South, of the rich world and the poor world. If the colonial world was, in his words, “a world cut in two,” our postcolonial world seems scarcely less so. Just consider the starkly different responses to the wars in Ukraine and Gaza — or South Africa’s case against Israel, on the charge of genocide — in the global north and the global south."
https://www.nytimes.com/2024/02/02/opinion/frantz-fanon-colonialism.html
Thiago Carvalho
boosted
The impact of digital adherence technologies on health outcomes in tuberculosis: A systematic review and meta-analysis https://www.medrxiv.org/content/10.1101/2024.01.31.24302115
Thiago Carvalho
boosted
Apply to be a 2024 ASAPbio Fellow!
📄gain a comprehensive overview of the preprint landscape
🧑🤝🧑connect with like-minded individuals
🎤develop your own preprint based talk
💡create and lead a new project
Thiago Carvalho
boosted
NASA engineers when their probe slams smack into the tetrahedron
“If you have growing numbers of researchers who are being strongly incentivised to publish just for the sake of publishing, while we have a growing number of journals making money from publishing the resulting articles, you have a perfect storm,” said Professor Marcus Munafo of Bristol University. “That is exactly what we have now.”
Thiago Carvalho
boosted
Researchers use supercomputer to determine whether 'molecules of life' can be formed naturally in right conditions.
#evolution #origins_of_life #AI
https://phys.org/news/2024-02-supercomputer-molecules-life-naturally-conditions.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
