Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Recently wrote for #NatureMedicine this postmortem of the Oxford/AZ mucosal Covid vaccine trial. The intranasal spray version of ChAdOx1 failed to induce strong antibody responses.
But the column also includes a bit on the positive outcome of CanSino's trial using an inhaler (approved as a booster for 2x Coronavac).
Thiago Carvalho
boosted
Thiago Carvalho
boosted
I have to say that this is such an elegant study from first principles in @PNASNews
“The abundance, biomass, and distribution of ants on Earth”. https://www.pnas.org/doi/10.1073/pnas.2201550119
Thiago Carvalho
boosted
Hi all! I'm a postdoc, about to start my lab at Penn studying metabolic fluxes in tumor and immune cells! Also i like bad science puns!
Thiago Carvalho
boosted
A Social media site for allergies called
Mast-cell-odon
Thiago Carvalho
boosted
Do you analyze #microbial growth data from a plate reader in #RStats?
Do you wish it was easier to import, organize, and merge your data?
Do you want to do model-free analyses of growth curves?
Now available: gcplyr, an R pkg in Open Beta https://github.com/mikeblazanin/gcplyr/
1/
"Day six
There’s something missing. I can’t quite put my finger on it. Oh yes: where are all the arseholes? Where are the people who want dinghies full of migrants to sink into a freezing sea? Where are the people who call us libtards? Where, now I come to think of it, are all the Tory MPs?"
Thiago Carvalho
boosted
The latest episode of the #EMBOPodcast is out today.
I spoke with Roberto di Lauro who's had a fascinating career at the NCI during the golden age of molecular biology there, in Naples - both at Federico II & running one of biology's mythical places, the Stazione Zoologica Anton Dohrn, and even served some time in the diplomatic core.
This was a fun talk about science, #SciencePolicy, #HistoryOfScience, #MolecularBiology, science in Italy and much more.
https://www.embo.org/podcasts/we-should-know-more-this-is-our-main-job/
Thiago Carvalho
boosted
RT @PepperMarion
As promised! @UW_Immunology is excited to announce two open faculty job postings! We are hiring up to TWO Assistant Professors and ONE Associate Professor. Intended start date September 2023. Diverse candidates encouraged to apply!
Aedes aegypti Dicer2 mutants
"Our Dicer2 null mutant line is viable and fertile, and only displays minor fitness defects despite being unable to produce siRNAs. The loss of Dicer2 affects early viral replication and systemic viral dissemination of four medically significant arboviruses (chikungunya, Mayaro, dengue, and #zika viruses) representing two viral families. However, measures of virus transmission potential indicate that Dicer2 null mutants and wild-type mosquitoes display an overall similar level of vector competence. Additionally, Dicer2 null mutants undergo significant virus-induced mortality during infection with #chikungunya virus, but not #dengue virus."
#siRNA #crispr #preprint
Thiago Carvalho
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@clathrin Neurobiology, cell biology & mindblowing imaging- opens so many more questions & throws dogma wide open 😮 ... A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. From the Clapham lab at Janelia. PMID: 36055200 DOI: 10.1016/j.cell.2022.07.026
Thiago Carvalho
boosted
#introduction Hello #sciencemastodon I am a cell biologist running a research group in the UK focused on membrane traffic and cell division in human cells. I aim to post mainly about science but also music, running and cycling.
Hashtags:
#cellbiology #microscopy #imageanalysis #membranetraffic #mitosis #cytoskeleton #cancer #academia #statistics #openscience #Rstats #igorpro #datascience #raspberrypi #generativeart #music #running #cycling
Thiago Carvalho
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RT @LukensJohnR
Review on the link between chronic stress, inflammation, and mood disorders
https://www.nature.com/articles/s41590-022-01321-z
Thiago Carvalho
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Please suggest a cool paper/preprint in your field in the last year or so!
For a course I teach, I am collecting papers on: cell/dev bio, microbio, neuro, maths/stats/CS/chem/phys applied to biology.
Students use one paper as the basis for a "research grant application" that they will write. So papers that are cool but also open doors to future study are ideal! Do you know one? It can be your own, I don't mind!
Last year's selection https://quantixed.org/2022/01/12/papers-for-md9a8-2022-edition/
Thiago Carvalho
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Here is the link to apply to our tenure-track Assistant Professor level positions. We seek early-career researchers working in #complexsystems, #networkscience, #computationalsocialscience, biomedical complexity, and related topics.
https://binghamton.interviewexchange.com/jobofferdetails.jsp?JOBID=155321
Thiago Carvalho
boosted
Immunotherapy can induce myocarditis but the mechanism has been poorly understood. A new report @nature@twitter.com today supports the culprit auto-antigen role of α-myosin and cytotoxic T-cells directed to it https://www.nature.com/articles/s41586-022-05432-3 by @MargaretAxelrod@twitter.com @BalkoLab@twitter.com
Thiago Carvalho
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In case you were wondering:
@the_node@mstdn.science
@J_Cell_Sci@mstdn.science
@focalplane_jcs@mstdn.science
Thiago Carvalho
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The LMB PhD Programme
@LMB_PhD is open to applications for starting next year.
PhD students interested in developing novel cryomicroscopy technology are welcome to apply: https://www2.mrc-lmb.cam.ac.uk/students/international-phd-programme/projects/christopher-russo/
To apply see: https://www2.mrc-lmb.cam.ac.uk/students/international-phd-programme/how-to-apply/
Thiago Carvalho
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RT @RaskoLab@twitter.com
Epigenetics ROCKS!
Who would have guessed chromatin accessibility (ie nucleosome-free regions) contributes substantially to alternative splicing in specific cells 😎🆒
https://tinyurl.com/2zestch2 @DNA_RNA_Uni@twitter.com @DNAmPapers@twitter.com @AEpiA@twitter.com @EpigenChromatin@twitter.com @ulfschmitz@twitter.com @Epigenetics@twitter.com
"But Earth’s rotation slows ever so slightly from year to year, and the astronomical second (like the astronomical day) has gradually grown longer than the atomic one. To compensate, starting in 1972, metrologists began occasionally inserting an extra second — a leap second — to the end of an atomic day. In effect, whenever atomic time is a full second ahead, it stops for a second to allow Earth to catch up. Ten leap seconds were added to the atomic time scale in 1972, and 27 more have been added since."
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
