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Hi everyone! Here's my #introduction . I'm a PhD candidate at Harvard University primarily studying how selective breeding and lifetime experience shape the brains of #workingdogs such as herding Border Collies and service dog Labrador Retrievers. I use #neuroimaging, #surveys, and behavioral experiments to answer my research questions. You can participate in my research with your dog by visiting caninebrains.org! I'm excited to be apart of the #Mastodon community

" To test the hypothesis that cephalopod limbs evolved by recruitment of an ancient gene regulatory network for appendage development that is conserved across Bilateria, we investigated arm and tentacle development in embryos of the cuttlefish, Sepia officinalis."

elifesciences.org/articles/438

RT @MucosalImmunol@twitter.com

Our special #Helminth edition of MI is online now: This issue is packed with #helminth reviews! From @debroski1@twitter.com @juaninclanrico@twitter.com: “Every cell is an immune cell; contributions of non-hematopoietic cells to anti-helminth immunity” nature.com/articles/s41385-022

🐦🔗: twitter.com/MucosalImmunol/sta

Hey Structural Biologists :protein:

#crystallography #MX #CryoEM #CryoET #NMR #SAXS #HDX #Alphafold #PDB #EMDB #StructuralBiology

I have created a group @strucbio .

If you tag this account in any relevant toot, it will automatically boost it.

So if you follow this account, any toots about structural biology should end up in your TL. The more people use it, the better it will be.

Boosting appreciated. :protein:

#Introduction.
I am a Senior Scientist @UW focusing on T cell #immunology interested in what constitutes the most beneficial T cell response to infection. Also fascinated by the complexities and oddities of non-mammalian immune systems.

Something people don’t know about me: In rare moments of quiet, I sketch (see work-in-progress pic).

I am here to keep up-to-date with the latest in science news, publishing, and banter. Might connect with the #indie music scene for some tunes too.

RT @NatureBiotech@twitter.com

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases bit.ly/3GEisKB

🐦🔗: twitter.com/NatureBiotech/stat

thought provoking Opinion article by Aru, Druke, Pikamae & Larkum:

'Mental navigation and the neural mechanisms of insight'

#neuroscience #creativity #hippocampus

50-day free access link:
authors.elsevier.com/a/1gAVLbo

This week the Cornell Lab of Ornithology released fine scale population trends maps for over 500 North American #birds based on #eBird data. These maps are the culmination of several years of research and development by the #eBird Status and Trends team, and all this work was only possible because of the amazing community of eBirders who contributed 43.8 million checklists to the dataset we used to estimate population trends.

Learn more and view the interactive maps at science.ebird.org/en/status-an

In preprints: humans, the new model organism

James Wells and Ziyuan Guo highlight three preprints that use hPSC-derived tissue to dissect human development and disease.

journals.biologists.com/dev/ar

Get in touch if you would like to write an ‘In preprints’ article for @Dev_journal. We’re particularly keen to see collaborations between junior and senior PIs, and between researchers who haven’t previously worked together.

#preprints #devbio #devbiol

"The room of containment, technically an “anechoic chamber,” is the quietest place on the planet — according to some. According to others, it’s more like the second-quietest. It is quieter than any place most people will ever go, unless they make a point of going to multiple anechoic chambers over the course of a lifetime."

nytimes.com/2022/11/23/magazin

Always wondered what is all the commotion about organoids? Wonder no more!
Here is our primer that describe basic principles, factors to consider when getting started with organoids, applications, limitations and community standards. Hope you enjoy it!

#organoids #paper #review

nature.com/articles/s43586-022

Thanks...

RT @DamonLisch@twitter.com

My son, who is color blind, sent me this resource. It really is worth keeping folks like him in mind when you make your figures. davidmathlogic.com/colorblind/

🐦🔗: twitter.com/DamonLisch/status/

The New York Times headline is funny, but the quote by Scott Aaronson is better - that is, more accurate:

“If this experiment has brought a wormhole into actual physical existence, then a strong case could be made that you, too, bring a wormhole into actual physical existence every time you sketch one with pen and paper.”

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New linocut of Bryn Celli Ddu, a Neolithic burial chamber near Llanddaniel Fab on Ynys Môn. The chamber overlays an earlier henge moment and its passage aligns with the sun such that the sun penetrates the chamber on the summer solstice. The Welsh name translates into English as The Mound in The Dark Grove. The prints are hand-pressed onto a lightly textured Japanese paper (Hosho Select) using a barren and silver spoon. I have limited the number of prints to 10 in total.

RT @ElowitzLab@twitter.com

In his 1952 classic, Turing showed that ≥2 interacting, continuously diffusing morphogens can spontaneously generate beautiful biological patterns. On a discrete cell lattice, we find that 1 morphogen is enough for stable spatially periodic patterns cell.com/cell-systems/retrieve

🐦🔗: twitter.com/ElowitzLab/status/

'Surprisingly, MMR-deficient lineages rapidly developed high-level resistance (>256 μg/mL) largely without corresponding fixed mutations or transcriptional changes in well-established resistance genes. Further investigation revealed that these isolates had paradoxically generated an early inactivating mutation in the mexB gene of the MexAB-OprM efflux pump, a primary mediator of CZA resistance in P. aeruginosa, potentially driving an evolutionary search for alternative resistance mechanisms.'

journals.plos.org/plosbiology/

There are four schools of thought that each have their own ideas on how scientific peer review can be improved. Wolfgang Kaltenbrunner, @stephenpinfield, Helen Woods and I have revised our paper on this topic doi.org/10.31235/osf.io/v8ghj. We have also created a visualization that summarizes the key tensions between the four schools. We are grateful to the reviewers of our paper for their very useful feedback.

Hey! Im a researcher of host-microbe interactions with a focus on bees! My research group is based at the Silwood Park campus of Imperial College London. We're particularly interested in exploring how microbes transmit & what their impact is on pollinator systems. Where possible we try to employ new techniques or combine multiple cutting-edge processes at once.

#Pollinators #parasites #microbiome #SilwoodPark #ImperialCollegeLondon #Ecology #Microbiology #ScienceMastodon #Biology #Evolution

RT @DanielKronauer
Shazam! Here is the reveal: ant pupae secrete their molting fluid, and larvae and adults consume it. This creates interdependencies across different ant developmental stages. Thanks also to all our collaborators at the various resource centers @RockefellerUniv! twitter.com/OrliSnir/status/15

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