Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Thirty years ago, in November 1992, Ishida, Honjo and their collaborators reported the discovery of the #PD1 gene in @embojournal

https://www.embopress.org/doi/abs/10.1002/j.1460-2075.1992.tb05481.x

I spoke with Tasuku Honjo, Pierre Golstein (whose team first cloned #CTLA4) & Facundo Batista about the discovery earlier this year.
The initial project had absolutely nothing to do with checkpoints or #immunotherapy

Listen to the full #EMBOPodcast episode at the link below or on pretty much any podcast app

#Immunology #HistoryScience #Cancer #CellDeath

https://www.embo.org/podcasts/from-cell-death-to-cancer-immunotherapy/

Day8: Lordiphosa andalusiaca—Our first #Advent species not in #Drosophila: a distinctive #Fly with a striking colour #polymorphism (https://brill.com/view/journals/anz/17/2/article-p275_3.xml - ours is a dark one). Lordiphosa like rotting plants http://www.drosophila.jp/jdd/class/030704/03070441.pdf and some species have sex combs https://doi.org/10.1111/evo.14564 . It gives us two lessons in systematics: [1] #Drosophilid #Taxonomy doesn’t match #Phylogeny https://academic.oup.com/gbe/article/13/8/evab179/6337980 ; [2] Do not let people play word games with your (sub)genera... cf. Phloridosa & Siphlodora

Really excited to launch @Dev_journal@twitter.com "Pathway to Independence Programme"

Are you, or do you know, a dev bio or stem cell researcher planning to apply for their 1st PI position in 2023?

Then this scheme is for you. See how to apply:

https://journals.biologists.com/dev/article/149/23/dev201456/285866/The-Pathway-to-Independence-programme-helping

Let’s make the science move to #mastodonmigration a definitive thing.
---
RT @cyrilpedia
The community is growing over there - I even have a range of science-Luis friends to choose from, with @lmvteixeira at

@lmvteixeira

& @LuisMateusRocha at

@lmrocha
https://twitter.com/CyrilPedia/status/1600525806924595200

So ends a historic attempt at global health equity: The board of Gavi votes this week on ending #Covax, even though some Gavi-supported countries are at <20% Covid vaccine coverage. The average among Gavi-countries is 52%. And 37 middle-income countries would be cut off after a one-time infusion of cash to take over Covid vaccination on their own. Thanks to vaccine nationalism, Omicron and a series of missteps, demand for shots globally is minimal. https://www.nytimes.com/2022/12/06/health/covid-vaccines-covax-gavi.html?unlocked_article_code=I0gswX0sD7xUortbHHQaakgy94bVmymnrTOO1hgGFmEc3tcgVF-HNYVVGRKFS3P6vVBTTqbeozQSAjd6eRsVq5FiPBmDQPJAUJhiecgkIqyzrq07Gzg2JzwRJJUOF7dd1tgP6dqQnzJ_F1cXJL5W5908i4b5mL6Kgd2vrRGu6TL1LYOqCzpcpr6xlONVg1LjyCUVWhsCLF7WSXr1ZiLTTIxjBUa_5C2QKzUnbcTR0BaIBVRTB1b5K5eRZcfBIfZ5MuYllgMc0M8ArvoddQMGP3kHHo1tlU1q8uVIuBLnSJFZDxc-Hgdh8Rnke_e9LDhUNgFeo6z_pWSMHZVmeir_RW_naQ&smid=share-url

Work with me, an amazing team at #ASM, and leading researchers and editors at #mBio, #mSphere and mSystems in making these #OpenAccess journals indispensable to everyone interested in the microbial sciences. US-based, remote work possible.

Please share broadly.

#microbiology #MicrobiologyJobs #openscience #sciencepublishing

https://recruiting.ultipro.com/AME1097AMESO/JobBoard/20f80d94-2e8b-41f1-81bd-2808157c95e1/OpportunityDetail?opportunityId=a230dbb9-d33f-4166-b20a-34e1d60e3d92

INVEST IN BETTER VENTILATION FOR SCHOOLS AND WORKPLACES

"For classrooms equipped with mechanical ventilation systems, the relative risk of infection of students decreased at least by 74% compared with a classroom with only natural ventilation,"

https://www.frontiersin.org/articles/10.3389/fpubh.2022.1087087/abstract

#Advent Day7: #Drosophila helvetica is our final (and most enigmatic?) obscura group fly. It is another common, small, dark, sap-flux feeder, but it is the only Eurasian member of the North American pseudoobscura/affinis clade https://www.jstor.org/stable/2422464 . With < 5 WOS-indexed papers, all I can say is that: it’s not hard to ID (sex combs or ovipositor); it is hard to keep in the lab; it has very simple courtship https://www.jstor.org/stable/pdf/4533126 ; and the genome has just been sequenced https://tolqc.cog.sanger.ac.uk/darwin/insects/Drosophila_helvetica/

California friends: I'll be in the area between December 8th and the 12th if you want to get coffee :) Starting in San Francisco (giving a seminar in
@stanford
on the 9th) and from there to L.A
to record an episode on the Huberman podcast
- can't wait and hope to see you there!

Interested in a PhD in AI, robotics or neuromorphic computing?
https://sussex.ac.uk/study/fees-funding/phd-funding/view/1403-Leverhulme-Doctoral-Scholarship-Programme:-be.AI---biomimetic-embodied-Artificial-Intelligence
Apply to the be.AI Leverhulme Doctoral Training Centre in biomimetic embodied AI http://sussex.ac.uk/ccnr/be_ai Application deadline 23 Feb '23

We are recruiting our last cohort of 6 PhD students for a September 2023 entry. Join a fantastic team featuring
@InsectNav @ProfAndyP
and me as directors, supervisors from @SNAC_Sussex @SussexEASy
and wider @EngInfSussex, at the beautiful Falmer Campus of
@SussexUni

Hi all, my #introduction! I lead a #neuroscience research lab at Emory University called the Perception and Action Lab. We study how the brain allows us to actively explore and learn about the world through body motion. We're particularly interested in modeling and understanding distributed computations across multiple brain areas, and how these computations change during hearing loss and other conditions. I mostly post about work but sometimes other things too!
https://lab.chris-rodgers.com/