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Hello, world! We are moving over from Twitter this week. This is a shared lab account for all members of our B cell immunology and preclinical vaccine research lab at the Ragon Institute. #TwitterMigration

We are looking for a lab manager! Please share this post with any friends looking for work in the Boston area: nature.com/naturecareers/job/l

TRANSPARENT FROGS
Resting glassfrogs increase transparency two- to threefold by removing ~89% of their RBCs from circulation and packing them within their liver.
science.org/doi/10.1126/scienc

Do you want to know what regulatory interactions underlie changes in gene expression or chromatin state in your model system? Do you have transcriptome or epigenome data? Consider using our free online regulatory genomics tools:
swissregulon.unibas.ch/pages/
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Host-#bacteriophage interactions in biofilms. @CareyNadell &co show that multispecies #bacterial #biofilm architecture qualitatively alters the community dynamics of matrix production, interspecific competition & bacteriophage propagation #PLOSBiology plos.io/3WAPv71

RT @JChengWSJ@twitter.com

WHO's emergencies director Mike Ryan: "In China, what's been reported is relatively low numbers of cases in ICUs, but anecdotally ICUs are filling up…I wouldn't like to say that China is…not telling us what's going on. I think they're behind the curve."
reut.rs/3jlRRbw

🐦🔗: twitter.com/JChengWSJ/status/1

For , an episode of the that aired this summer:

Orian Shirihai tells the story of a classic @embojournal paper on the mitochondrial life cycle.

The episode, "Fuse or Die" highlights the importance of my personal nemesis, the well-organised lab notebook.

embo.org/podcasts/fuse-or-die-

'Many hospitals offer exclusive concierge services to the rich. But emergency rooms are built around the premise of medical triage: that the sickest patients, regardless of their ability to pay, are treated first. Everyone else has to wait.

At NYU Langone, one of the country’s pre-eminent medical institutions, some doctors said that process had been upended.'

nytimes.com/2022/12/22/health/

"The privileged treatment is part of a broader pattern, a Times investigation found. For years, NYU’s emergency room in Manhattan has secretly given priority to donors, trustees, politicians, celebrities, and their friends and family, according to 45 medical workers, internal hospital records and other confidential documents reviewed by The Times."

nytimes.com/2022/12/22/health/

“Wound Man” is an illustration which first appeared in European surgical texts during the Middle Ages. It laid out schematically the various wounds a person might suffer in battle or in accidents, often with surrounding or accompanying text stating treatments for the these injuries. This particular “Wound Man” dates to the 15th century and is part of the Wellcome Collection in London.

Which “wound” are you today?!

#histodons #introduction #followback #weird #history #histmed #histsci

"Glyco-binding domain chimeric antigen receptors as a new option for cancer immunotherapy"

nature.com/articles/s41434-022

RT @samhaselby@twitter.com

Did the first Americans arrive 15,000 years ago, 40,000 years ago, or 130,000 years ago? Geneticists and archeologists are working with indigenous peoples to try to figure it out. The great @JenniferRaff@twitter.com gives us a glimpse of how it is going. aeon.co/essays/the-first-ameri via @aeonmag@twitter.com

🐦🔗: twitter.com/samhaselby/status/

"Here, we tested the ability of the major sphingolipids inositol phosphorylceramide (IPC), and ceramide to shelter ergosterol by preventing binding and cytotoxicity of the sterol-specific toxins streptolysin O and perfringolysin O using flow cytometry. In contrast to mammalian systems, Leishmania sphingolipids did not preclude toxin binding to sterols in the membrane. However, IPC interfered with cytotoxicity."

biorxiv.org/content/10.1101/20

a single-cell strategy to precisely define the unperturbed peripheral blood HIV-infected memory CD4+ T cell reservoir from ART-treated people living with HIV (ART-PLWH) via the presence of integrated accessible proviral DNA in concert with epigenetic and cell surface protein profiling.
pubmed-ncbi-nlm-nih-gov.insb.b

New paper by Yunyao Xie from my lab. A dopaminergic reward prediction error signal shapes maternal behavior in mice cell.com/neuron/fulltext/S0896

This may be my favorite paper that I have ever published.

RT @PilhoferLab@twitter.com

Asgard archaea reignited discussions about the tree of life 🦠 But do they have eukaryotic features? YES!! 🤩 Check out our new paper @Nature@twitter.com by @F_Wollweber@twitter.com and @xujw_thu@twitter.com, in an exciting collaboration with the Schleper lab @Archaea_Vienna@twitter.com. nature.com/articles/s41586-022
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"Household versus incentive-based contact investigation for #tuberculosis in rural South Africa: a cluster-randomized trial"

Incentive-based (small cash incentives for index and up to ten contacts) approach as effective as traditional household-based. No incompatible approaches , but complementary.

academic.oup.com/cid/advance-a

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