Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
#Cellbiology Decoding how two structurally similar proteins support #autophagy, a form of cellular self-maintenance that often becomes compromised in cancer, neurodegeneration, and other conditions. @SciSignal
https://www.science.org/doi/10.1126/scisignal.abo4457
Thiago Carvalho
boosted
If you're trying to convince your Canadian friends to get set up on Mastodon but they don't know where to start, pass along the link to this listing of Canadian instances: #topoli #onpoli #cdnpoli
https://mastodonserver.ca/
"By conducting a pangenomic screen of the plant pathogen #Pseudomonas syringae, we found 13 type III effectors that potentially possess NADase activities, indicating that NAD+ manipulation is an important virulence mechanism."
"Among other things, this would mean reforming the agency’s much-maligned communications apparatus and honing its ability to capably respond to public health emergencies in a way that it has singularly failed to do during the Covid pandemic. If enacted, this would represent the kind of top-to-bottom revamp that rarely, if ever, happens at most federal agencies."
@gregggonsalves @thenation
https://www.thenation.com/article/society/cdc-reform-rochelle-walensky/
Thiago Carvalho
boosted
'Russian poet, body-builder & futurist Vladimir Goltsshmidt hypnotizing a chicken, 1923'
Thiago Carvalho
boosted
Lady Charlotte Hugonin Murchison died February, 9 1869. An avid fossil collector, she introduced her husband Sir Roderick Impey Murchison to the world of #geology. The "Ammonites Murchisonae" is named after her.
Thiago Carvalho
boosted
#CellMigration for house cleaning!
Immune cell (i.e. #DendriticCell), moves to remove 2 death cells (arrows)
This is pretty much what happens in our body when normal tissue cells die, they are scanned & removed by leukocytes (also macrophages)
#scicomm @cellcommlab @focalplane
"Vaccines that resulted in speedy delivery of antigens to follicles preserved intact antigen and generated better antibody responses. These findings may have implications for the design of vaccines against difficult to neutralize or genetically variable pathogens"
#Immunology #ImmunologicalMemory #Antibody #GerminalCenter #Bcells #Vaccine
Thiago Carvalho
boosted
Our February issue is online today!📢
👉 Read our articles on #AlzheimersDisease, #stroke, #CADASIL, #leukemia, #Qfever, #ChronicKidneyDisease, #DiabeticWoundHealing (our cover) and more!
👉 Review on #PanethCells in intestinal homeostasis & organismal health, Commentaries on the functions of the #Elongator in health & disease, and on the development of allogeneic #iPSC -based therapy
🗞️ Fully #openaccess: https://www.embopress.org/toc/17574684/2023/15/2
Thiago Carvalho
boosted
Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS
The FT is featuring phage therapy in the context of the antibiotic resistance crisis.
https://www.ft.com/content/c6df6bc4-f87e-4adb-bc92-97985f031550
ICYMI, we did an episode of the #EMBOPodcast featuring pediatric infectious disease physician Ameneh Khatami who published a single patient study in @EmboMolMed
It's the story of a seven-year-old girl infected with a multi-drug resistant #Pseudomonas strain who underwent #PhageTherapy.
https://www.embo.org/podcasts/the-enemy-of-my-enemy/
#antibioticresistance
#PersonalizedMedicine #Phage #Microbiology
If I recall correctly, Human-Android relations was C3PO's job description.
"Your work future could depend on how well you can talk to AI."
Thiago Carvalho
boosted
If you're a group leader interested in writing an 'In preprints' article for the #devbio and #stemcell community please get in touch!
Learn more about 'In preprints' articles in this introductory Editorial:
https://journals.biologists.com/dev/article/149/7/dev200711/274912/Preprints-in-Development
And see the growing collection of #preprint curations here:
https://journals.biologists.com/dev/collection/7815/In-preprints
"The Angelika Amon Young Scientist Award at MIT's Koch Institute is an endowed prize established in 2021 by family and friends to support two graduate students in the life sciences or biomedical research from institutions outside the United States who embody Dr. Amon’s infectious enthusiasm for discovery science."
Thiago Carvalho
boosted
In EMBO Journal issue 3:
Host #mucins negotiate peace with #toxigenic #Vibrio
Cytosolic #stressgranules relieve nuclear #ubiquitin-#proteasome system
#Smoothened #cholesterylation and ER exit links in #Hedgehog signaling
Developmental #cellfate decision control by #chromatin reader #TRIM33
Cover by Kimon Lemonides, Helen Walden et al
Interim good news from China - the covid wave may be subsiding
"Los datos publicados por las autoridades sanitarias muestran que el último brote de infecciones en China, el más severo desde el inicio de la pandemia, ha empezado a ceder después de alcanzar el pico el pasado 22 de diciembre, jornada en la que se registraron 6,94 millones de nuevos casos."
Thiago Carvalho
boosted
Thiago Carvalho
boosted
In this article, Sophie Kraunsoe et al. explore the role of STAT3 and TFCP2L1 in #epiblast renewal, and find that requirements for stem cell #renewal in the dish are different to those in the #embryo:
Check out this interview with Sophie to find out more about the story behind the paper:
https://journals.biologists.com/bio/article/12/1/bio059812/286607/First-person-Sophie-Kraunsoe
#Pluripotency #Diapause #Blastocyst #StemCells #Science #BiologyOpen #Biology #Development #DevBio
Thiago Carvalho
boosted
Elon Musk’s Twitter fails first EU disinformation test https://www.politico.eu/article/elon-musk-twitter-fails-eu-first-disinformation-test-digital-services-act/?utm_source=RSS_Feed&utm_medium=RSS&utm_campaign=RSS_Syndication #DigitalServicesAct #Disinformation #SocialMedia #Algorithms #Technology #Companies #Platforms #Labels #Safety
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
