RT @NASEM_Health
.@cdc’s new report shows sexually-transmitted infections #STI cases continue to rise, making STI prevention and other forms of sexual health more important than ever: https://www.cdc.gov/std/statistics/2021/default.htm (1/2)
My latest Clinical Pipeline column for #NatureMedicine is a look at zuranolone, a new antidepressant developed by Sage & Biogen, targeting the GABA pathway.
#drugdiscovery #drugdevelopment #depression #GABA #neuroscience
'The Portuguese Heritage Society estimates that up to 90 percent of Portuguese Americans descend from the Azores.'
"Uno de los planes del proyecto UnCan es afinar la hoja de ruta para crear un centro europeo de datos sobre cáncer con aportaciones de todos los países: la información biomédica se integrará con otro tipo de datos, como observaciones geográficas o de estilo de vida, para ponerlos a disposición de la comunidad científica y avanzar en la comprensión de la enfermedad desde todas las aristas posibles."
RT @KevinWNg
Excited to share our work on B cells in lung cancer, published today in @Nature!
'The burden of navigating Covid’s risks now falls on the individual, and what “post-pandemic” means for one person or community, like Ninety-Fifth Street Elementary, looks wildly different than it does for others.'
'We show here that in vitro exposure to SARS-CoV-2 activates the expression of the human endogenous retrovirus (HERV) HERV-W proinflammatory envelope protein (ENV) in peripheral blood mononuclear cells from a subset of healthy donors, in ACE2 receptor and infection-independent manner.'
https://www.cell.com/iscience/fulltext/S2589-0042%2823%2900681-8
'Thus, identifying the subset of patients for whom public neoantigens are relevant targets is a major challenge. Nevertheless, the ability provided by the expansion of standard-of-care next-generation sequencing to screen patients affords the opportunity for off-the-shelf precision immunotherapies against public neoantigens that would be broadly applicable to many patients and would have tremendous advantages in scalability relative to targeting private neoantigens'
#Immunology #Immunotherapy #TumorImmunology
"Two concurrent outbreaks of the Marburg virus, a close cousin of Ebola that can kill as many as 90 percent of the people it infects, are raising critical questions about the behavior of this mysterious bat-borne pathogen and global efforts to prepare for potential pandemics."
#Marburg #Outbreak #publichealth #virology
https://www.nytimes.com/2023/04/03/health/marburg-outbreak-vaccine-treatment.html
A great resource for teaching manuscript writing.
"Familiarity with the process of writing a scientific manuscript and receiving peer reviews often leads to a more focused and driven experimental approach as well as a better understanding of the scientific literature. To jump-start this training, we developed a protocol for teaching manuscript writing and reviewing in a course, appropriate for new graduate or upper-level undergraduate students in biology."
https://qubeshub.org/community/groups/coursesource/publications?id=3708&v=1
Really exciting program @pezcoller and in a very lovely location. I remember my invitation to @CIBIO_UniTrento so fondly - great students, some of whom I am still in touch with, cool science and fantastic pasta in this lovely small restaurant close to the institute. 👌
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RT @pezcoller
Excited to share the program of 2023 Pezcoller Symposium, with a tremendous lineup of speakers!
Mark it on your calendar:
💡 NEW TECHNOLOGIES FOR STUDYING…
https://twitter.com/pezcoller/status/1646047407568744450
We REALLY need the government to listen and think, years of austerity have left public sector workers underpaid and the infrastructure, NHS, School etc massively under resourced
‼️A few days left to apply for a fellowship to attend EVOLUTION IN ACTION in the south of Switzerland‼️
More information:
https://www.evolution.uzh.ch/en/conference/financialsupport.html
Grab the opportunity to discuss your research with top-notch scientists at a small but mighty conference!
❓❓If you have any questions, do not hesitate to contact us.❓❓
👉Check out our program and register now!
🧬 Interesting article in @Gizmodo on the 20th anniversary of the #HumanGenomeProject that features our Director Emeritus Hans Lehrach, who was involved in sequencing the first human genome.
https://gizmodo.com/human-genome-project-20th-anniversary-dna-health-1850322521
'Our study reveals that probiotic Lactobacillus reuteri (Lr) translocates to, colonizes, and persists within melanoma, where via its released dietary tryptophan catabolite I3A, it locally promotes interferon-γ-producing CD8 T cells, thereby bolstering ICI.'
The structure of four related forms of actin sheds light on how this protein adapted to suit the varied roles it plays in the cell. https://elifesciences.org/digests/82015/learning-from-structure?utm_source=mastodon&utm_medium=social&utm_campaign=organic
A great resource for teaching manuscript writing.
"Familiarity with the process of writing a scientific manuscript and receiving peer reviews often leads to a more focused and driven experimental approach as well as a better understanding of the scientific literature. To jump-start this training, we developed a protocol for teaching manuscript writing and reviewing in a course, appropriate for new graduate or upper-level undergraduate students in biology."
https://qubeshub.org/community/groups/coursesource/publications?id=3708&v=1
#IDMastodon @Cureus The more you know ,the more you know nothing #CovidIsNotOver . #COVID19 can caused severe GI symptoms 😱 This #CaseReport sheds light on a 62 yr-old male who presented w/ abdominal pain, hematemesis, bloody diarrhea & abdominal distention.
https://www.cureus.com/articles/128861-paralytic-ileus-as-an-extra-pulmonary-manifestation-of-covid-19?utm_source=twitter&utm_medium=social#!/
'What’s clear is that the Brexit idea about how Britain’s withdrawal from Europe would work depended on a vague assumption that the E.U. would throw Ireland under the bus, and that the U.S. would, too, in the rush to conclude a free-trade deal with Britain. That didn’t happen.'
https://www.newyorker.com/magazine/2023/04/10/there-will-be-fire-rory-carroll-book-review-ireland
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com